Displaying drugs 451 - 475 of 1063 in total
Mosedipimod
Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced Neutropenia.
Investigational
Matched Synonyms: … 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol …
Matched Description: … Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced …
Matched Description: … Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced …
Protein C
Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface...
Approved
Matched Synonyms: … blood coagulation factor XIV ... Human protein C ... Protein C human …
Matched Description: … APC exerts its effect by inactivating essential components of the coagulation cascade (specifically factors ... V and VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation ... thrombosis and purpura fulminans. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Biological Factors ... Blood Coagulation Factor Inhibitors …
Matched Description: … APC exerts its effect by inactivating essential components of the coagulation cascade (specifically factors ... V and VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation ... thrombosis and purpura fulminans. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Biological Factors ... Blood Coagulation Factor Inhibitors …
Cefotaxime
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Products: … Cefotaxime and Dextrose …
Matched Products: … Cefotaxime and Dextrose …
Human C1-esterase inhibitor
C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways.[L16586, L16606]
This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a...
Approved
Matched Synonyms: … C1-inhibiting factor ... C1 inhibitor human ... C1 inhibitor (human) …
Matched Name: … Human C1-esterase inhibitor …
Matched Description: … The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... [L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE ... The disease is characterized by acute attacks of painful, and in some cases, fatal swelling of several …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Immunologic Factors …
Matched Products: … HAEGARDA C1 Esterase Inhibitor Subcutaneous (Human) …
Matched Name: … Human C1-esterase inhibitor …
Matched Description: … The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... [L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE ... The disease is characterized by acute attacks of painful, and in some cases, fatal swelling of several …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Immunologic Factors …
Matched Products: … HAEGARDA C1 Esterase Inhibitor Subcutaneous (Human) …
Sargramostim
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Approved
Investigational
Matched Synonyms: … Recombinant human granulocyte-macrophage colony stimulating factor …
Matched Description: … Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed …
Matched Categories: … Leukocyte Growth Factor ... Hematopoietic Cell Growth Factors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed …
Matched Categories: … Leukocyte Growth Factor ... Hematopoietic Cell Growth Factors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Nesiritide
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Approved
Investigational
Matched Synonyms: … Human brain natriuretic factor-32 …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Apitegromab
Apitegromab is under investigation in clinical trial NCT03921528 (An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy).
Investigational
Matched Synonyms: … Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk ... -015 .gamma.4-chain), disulfide with human monoclonal srk-015 .lambda. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Preimplantation factor
Preimplantation factor is under investigation in clinical trial NCT03593460 (Phase II Autoimmune Hepatitis).
Investigational
Matched Synonyms: … Synthetic PreImplantation Factor …
Matched Name: … Preimplantation factor …
Matched Description: … Preimplantation factor is under investigation in clinical trial NCT03593460 (Phase II Autoimmune Hepatitis …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Preimplantation factor …
Matched Description: … Preimplantation factor is under investigation in clinical trial NCT03593460 (Phase II Autoimmune Hepatitis …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Palmitoyl-Linoleoyl Phosphatidylcholine
Experimental
Matched Name: … Palmitoyl-Linoleoyl Phosphatidylcholine …
Myelin basic protein
Investigational
Matched Name: … Myelin basic protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Myelin Basic Protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Myelin Basic Protein …
Ulenistamab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human pancreatic adenocarcinoma up-regulated factor) (human-mus musculus monoclonal ... pbp1510 .gamma.1-chain), disulfide with human-mus musculus monoclonal pbp1510 .kappa. …
Retlirafusp alfa
Investigational
Matched Synonyms: … peptide linker ((ggggs)4g) fusion protein with 20-136-type II transforming growth factor .beta. receptor ... (human isoform 1), disulfide with (85-glutamic acid) human-mus musculus monoclonal SHR-1316 .kappa. ... programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion protein with …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Palmidrol
A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In Italy and Spain (300 mg and 600 mg tablets).
Experimental
Nutraceutical
Matched Synonyms: … Palmitoyl-EA ... Palmitoyl ethanolamide …
Matched Description: … Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes ... In Italy and Spain (300 mg and 600 mg tablets). …
Matched Categories: … Cannabinoids and similars ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes ... In Italy and Spain (300 mg and 600 mg tablets). …
Matched Categories: … Cannabinoids and similars ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Alpha-1-proteinase inhibitor
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … .Alpha.1-proteinase inhibitor human ... Alfa 1-proteinase inhibitor (human) ... Alpha 1-proteinase inhibitor human …
Matched Description: … fractionation followed by PEG and zinc chloride fractionation. ... Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol …
Matched Categories: … Human alpha-1 Proteinase Inhibitor ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Alpha1-proteinase Inhibitor (human) …
Matched Description: … fractionation followed by PEG and zinc chloride fractionation. ... Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol …
Matched Categories: … Human alpha-1 Proteinase Inhibitor ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Alpha1-proteinase Inhibitor (human) …
Rabies immune globulin, human
IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced rabies vaccine.
Persons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have not been demonstrated should...
Approved
Matched Synonyms: … Rabies immune globulin human ... Rabies immune globulin,human ... Rabies immune globulin (human) …
Matched Name: … Rabies immune globulin, human …
Matched Description: … adequate antibody levels have not been demonstrated should receive full post-exposure prophylaxis with RIG and ... Recommendations for passive and/or active immunization after exposure to an animal suspected of having ... Advisory Committee on Immunization (NACI), the Advisory Committee on Immunization Practices (ACIP), and …
Matched Categories: … Human Rabies Immune Globulins …
Matched Products: … Hyperab Rabies Immune Globulin Human …
Matched Name: … Rabies immune globulin, human …
Matched Description: … adequate antibody levels have not been demonstrated should receive full post-exposure prophylaxis with RIG and ... Recommendations for passive and/or active immunization after exposure to an animal suspected of having ... Advisory Committee on Immunization (NACI), the Advisory Committee on Immunization Practices (ACIP), and …
Matched Categories: … Human Rabies Immune Globulins …
Matched Products: … Hyperab Rabies Immune Globulin Human …
MDX-018
MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation. Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system. Other possible indications include chronic obstructive pulmonary disease (COPD)...
Investigational
Matched International brands: … HuMax-Inflam …
Matched Description: … In pre-clinical studies, HuMax-Inflam has been shown to inhibit tumor growth in tumor models using primary ... 8) and may have potential application in oncology and inflammation. ... Other possible indications include chronic obstructive pulmonary disease (COPD) and pustular dermatoses …
Matched Description: … In pre-clinical studies, HuMax-Inflam has been shown to inhibit tumor growth in tumor models using primary ... 8) and may have potential application in oncology and inflammation. ... Other possible indications include chronic obstructive pulmonary disease (COPD) and pustular dermatoses …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … protein with human tumor necrosis factor .alpha., trimer ... Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion …
Bismuth subgallate
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Synonyms: … gallic acid bismuth basic salt ... basic bismuth 3,4,5-trihydroxybenzoate …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents …
Plasma protein fraction (human)
The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. This biologic should come...
Approved
Matched Synonyms: … Human plasma protein ... Human plasma proteins ... Human plasma protein fraction …
Matched Name: … Plasma protein fraction (human) …
Matched Description: … of albumin and globulin derived from human plasma. ... [L2262] The proteins in PPFh are stabilized with sodium caprylate and acetyltryptophan and it contains ... some electrolytes such as sodium, potassium and chloride. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Serum Albumin …
Matched Products: … Plasma Protein Fraction (human) Protenate …
Matched Name: … Plasma protein fraction (human) …
Matched Description: … of albumin and globulin derived from human plasma. ... [L2262] The proteins in PPFh are stabilized with sodium caprylate and acetyltryptophan and it contains ... some electrolytes such as sodium, potassium and chloride. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Serum Albumin …
Matched Products: … Plasma Protein Fraction (human) Protenate …
Ciprofloxacin
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493]
The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Fluocinolone Acetonide …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Drug-Related Side Effects and Adverse Reactions ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% ... CIPRO BASICS 250MG FILMTAB …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Fluocinolone Acetonide …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Drug-Related Side Effects and Adverse Reactions ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% ... CIPRO BASICS 250MG FILMTAB …
Cerliponase alfa
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Immature human tripeptidyl-peptidase 1 ... Immature cell growth-inhibiting gene 1 protein …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells
Investigational
Matched Name: … Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells …
Ordesekimab
Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease).
Investigational
Matched Synonyms: … Humax IL15 ... Humax-IL 15 ... Human IgG1 anti-IL-15 monoclonal antibody …
Matched Description: … Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ordesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Giroctocogene fitelparvovec
Giroctocogene fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a Adults).
Investigational
Matched Synonyms: … factor viii-specifying) ... Dna (recombinant adeno-associated virus 6 vector pf-07055480 human b-domain-deleted blood-coagulation ... Aav2/6-b-domain-deleted blood coagulation factor viii …
Matched Description: … fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and …
Matched Description: … fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and …
N-Methylmesoporphyrin containing copper
Experimental
Matched Synonyms: … 3-[18-(2-Carboxyethyl)-7,12-diethyl-3,8,13,17,23-pentamethylporphyrin-21-id-2-yl]propanoic acid;copper …
Matched Name: … N-Methylmesoporphyrin containing copper …
Matched Iupac: … lambda1-copper(1+) 4,20-bis(2-carboxyethyl)-10,15-diethyl-5,9,14,19,23-pentamethyl-21,22,23,24-tetraazapentacyclo …
Matched Name: … N-Methylmesoporphyrin containing copper …
Matched Iupac: … lambda1-copper(1+) 4,20-bis(2-carboxyethyl)-10,15-diethyl-5,9,14,19,23-pentamethyl-21,22,23,24-tetraazapentacyclo …
Displaying drugs 451 - 475 of 1063 in total