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Displaying drugs 551 - 575 of 770 in total

Tedizolid phosphate

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … Tedizolid phosphate ... Torezolid phosphate ... fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate …
Matched Name: … Tedizolid phosphate …
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and …

Flurbiprofen

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and ... formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …

beta-D-glucose 6-phosphate

Experimental
Matched Synonyms: … β-D-glucose 6-phosphate ... beta-D-glucose-6-phosphate ... beta-D-glucose 6-(dihydrogen phosphate) …
Matched Name: … beta-D-glucose 6-phosphate …

Ustekinumab

Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice. It is a targeted biologic disease-modifying anti-rheumatic drug (bDMARDs) that...
Approved
Investigational
Matched Description: … and subcutaneous formulations of the drug based on the dosing schedule and condition being treated. ... the interleukin (IL)-12 and IL-23 cytokines. ... IL-23, which are cytokines that are involved in immune and inflammatory responses. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Stelara Solution for Injection in Pre-Filled Syringe 90 mg/1 mL ... Stelara Solution for Injection in Pre-Filled Syringe 45 mg/0.5mL …

Acazicolcept

Investigational
Matched Synonyms: … cell costimulator ligand variant immunoglobulin domain designed to inhibit simultaneously the CD28 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

alpha-D-mannose 6-phosphate

Experimental
Matched Synonyms: … α-D-mannose 6-phosphate ... alpha-D-Mannopyranose 6-phosphate …
Matched Name: … alpha-D-mannose 6-phosphate …

Lipegfilgrastim

Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology . It is used as an alternate to DB00019 for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia. Since July 2013, lipegfilgrastim...
Approved
Investigational
Matched Description: … Neutropenia and febrile neutropenia (FN) are frequent and potentially fatal complications that occur ... life-threatening infection and sepsis. ... It aims to reduce the duration of neutropenia and the incidence of febrile neutropenia. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … LONQUEX SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 6MG/0.6ML …

Guanosine-3'-monophosphate-5'-diphosphate

Experimental
Matched Synonyms: … Guanosine 3'-(dihydrogen phosphate) 5'-(trihydrogen diphosphate) …
Matched Iupac: … ,5R)-4-hydroxy-5-(6-hydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-(phosphonooxy)oxolan-2-yl]methoxy})phosphoryl …

Insulin degludec

Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … tissues such as the liver, fat cells, and skeletal muscle. ... inhibits lipolysis and proteolysis among many other functions. ... degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and …
Matched Mixtures name: … Xultophy Pre-filled Pen …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... insulin degludec and insulin aspart ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 100 U/ML ... TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 200 U/ML …

Clobazam

Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Description: … , Frisium, Urbanyl, and others. ... children aged two years and older. ... and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Matched Products: … ASABIUM …

Aripiprazole

Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Description: … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... of alpha-adrenergic and 5-HT2A receptors. ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and …
Matched Categories: … Aripiprazole and prodrugs …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG …

L-histidinol phosphate

Experimental
Matched Synonyms: … phosphoric acid mono-[2-amino-3-(3H-imidazol-4-yl)-propyl]ester …
Matched Name: … L-histidinol phosphate …

Insulin detemir

Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Description: … tissues such as the liver, fat cells, and skeletal muscle. ... inhibits lipolysis and proteolysis among many other functions. ... Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Levemir® FlexPen® 100 U/ml Solution for Injection in Pre-filled Pen …

beta-D-galactose 6-phosphate

Experimental
Matched Synonyms: … beta-galactose-6-phosphate …
Matched Name: … beta-D-galactose 6-phosphate …

OXI-4503

OXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular disrupting agent (VDA). In addition, however, preclinical data demonstrates...
Investigational
Matched Synonyms: … Combretastatin A-1 bis(phosphate) …
Matched Description: … OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular ... OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. ... , preclinical data demonstrates that OXI-4503 is metabolized by oxidative enzymes (e.g., tyrosinase and …
Matched Categories: … Phosphate salts ... Phosphoric Acids ... Phosphorus Acids ... Phosphorus Compounds …

2-phospho-D-glyceric acid

A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration.
Experimental
Matched Synonyms: … D-glycerate 2-phosphate …

Ascorbyl phosphate

Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ascorbyl phosphate and sodium ascorbyl phosphate. These salts are present in cosmetic products at concentrations ranging from 0.001 % to 3% . As vitamin C is susceptible to breakdown of compound...
Approved
Matched Name: … Ascorbyl phosphate …
Matched Description: … ascorbyl phosphate and sodium ascorbyl phosphate. ... Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ... phosphate, along with other Vitamin C derivatives, acts as an active and stable precursor of vitamin …
Matched Salts name: … Magnesium ascorbyl phosphate …
Matched Categories: … Vitamin C and analogues …

Ascorbic acid

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Description: … Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and ... It is found naturally in citrus fruits and many vegetables. ... Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic …
Matched Mixtures name: … Milk Calcium With Vitamins C, D, and Phosphorous ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET ... Taron-prex Prenatal …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Vitamin C and analogues ... Genito Urinary System and Sex Hormones ... ascorbic acid (vit C) and calcium …
Matched Products: … Sodium Ascorbate and Ascorbic Acid Pwr ... Vit.c With N-M.bioflav.rose Hips and Rutin ... Timed Release and Esterified Vitamin C-1000 …

Denosumab

Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss ... [A263071] Chemically, it consists of 2 heavy and 2 light chains, with each light chain consisting of ... 215 amino acids and each heavy chain consisting of 448 amino acids with 4 intramolecular disulfides. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Prolia Solution for Injection 60mg Pre-filled Syringe …

Paratoulene phosphate

Experimental
Matched Name: … Paratoulene phosphate …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Cytidine 3'-monophosphate

Experimental
Matched Synonyms: … Cytidine 3'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

alpha-D-glucose 6-phosphate

Experimental
Matched Synonyms: … alpha-D-Glucopyranose 6-phosphate …
Matched Name: … alpha-D-glucose 6-phosphate …

Guanosine-2'-monophosphate

Experimental
Matched Synonyms: … Guanosine 2'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

beta-D-arabinofuranose 5-phosphate

Experimental
Matched Synonyms: … β-D-arabinofuranose 5-phosphate …
Matched Name: … beta-D-arabinofuranose 5-phosphate …

Somatrogon

Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … adolescence and regulating metabolic function in adulthood. ... of somatrogon and allows its once-weekly dosing. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists …
Displaying drugs 551 - 575 of 770 in total