Displaying drugs 726 - 750 of 923 in total
Aldesleukin
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … 125-L-serine-2-133-interleukin 2 (human reduced) …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... codon for this amino acid was deleted during the genetic engineering procedure; c) the molecule has serine ... Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... codon for this amino acid was deleted during the genetic engineering procedure; c) the molecule has serine ... Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
N-[1H-INDOL-3-YL-ACETYL]VALINE ACID
Experimental
Matched Name: … N-[1H-INDOL-3-YL-ACETYL]VALINE ACID …
Serinus canaria feather
Canary feather is used in allergenic testing.
Approved
Matched Name: … Serinus canaria feather …
Matched Categories: … Increased Histamine Release …
Matched Categories: … Increased Histamine Release …
AMY-101
AMY-101, also known as compstatin 40, is a peptidic inhibitor of the central complement component C3. AMY-101 is under investigation in clinical trial NCT03694444 (A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis).
Investigational
Matched Synonyms: … S3,S13-Cyclo(D-tyrolsyl-L-isoleucyl-L-cysteinyl-L-valyl-1-methyl-L-tryptophyl-L-glutaminyl-L-aspartyl-L-tryptophyl-N-methyl-L-glycyl-L-alanyl-L-histidyl-L-arginyl-L-cysteinyl-N-methyl-L-isoleucinamide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sabatolimab
Sabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).).
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline,de-c-terminal-lysine), anti-(human hepatitis virus a cellular receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Cycloserine
Antibiotic substance produced by Streptomyces garyphalus.
Approved
Matched Synonyms: … cyclo-D-Serine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Linaclotide
Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Synonyms: … L-TYROSINE, L-CYSTEINYL-L-CYSTEINYL-L-.ALPHA. ... (9-L-TYROSINE)HEAT-STABLE ENTEROTOXIN (ESCHERICHIA COLI)-(6-19)-PEPTIDE …
Matched Description: … Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C ... [A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013 ... [A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Description: … Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C ... [A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013 ... [A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Desmeninol
Experimental
Matched Synonyms: … Methionine hydroxy analog …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
PR1 leukemia peptide vaccine
PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … L-VALINE, L-VALYL-L-LEUCYL-L-GLUTAMINYL-L-.ALPHA. …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and …
Piperaquine
Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative DB11638 as part of...
Approved
Experimental
Investigational
Matched Synonyms: … 1,3-bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propane …
Matched Description: … Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550 ... Its use declined in the 1980's as piperaquine resistant strains of *Plasmodium falciparum* appeared and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... artenimol and piperaquine ... arterolane and piperaquine ... artemisinin and piperaquine …
Matched Description: … Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550 ... Its use declined in the 1980's as piperaquine resistant strains of *Plasmodium falciparum* appeared and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... artenimol and piperaquine ... arterolane and piperaquine ... artemisinin and piperaquine …
Penicillamine
Penicillamine is a pharmaceutical of the chelator class. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine). It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Approved
Matched Synonyms: … 3-mercapto-D-valine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Penicillamine and Similar Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Penicillamine and Similar Agents …
TERT-572
Investigational
Matched Synonyms: … L-arginyl-l-leucyl-l-phenylalanyl-l-phenylalanyl-l-tyrosyl-l-arginyl-l-lysyl-l-seryl-l-valine ... L-valine, l-arginyl-l-leucyl-l-phenylalanyl-l-phenylalanyl-l-tyrosyl-l-arginyl-l-lysyl-l-seryl- …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Para-Iodo-D-Phenylalanine Hydroxamic Acid
Experimental
Matched Name: … Para-Iodo-D-Phenylalanine Hydroxamic Acid …
(S)-propane-1,2-diol
(S)-propane-1,2-diol is a clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Experimental
Matched Synonyms: … (S)-propane-1,2-diol …
Matched Name: … (S)-propane-1,2-diol …
Matched Iupac: … (2S)-propane-1,2-diol …
Matched Description: … (S)-propane-1,2-diol is a clear, colorless, viscous organic solvent and diluent used in pharmaceutical …
Matched Name: … (S)-propane-1,2-diol …
Matched Iupac: … (2S)-propane-1,2-diol …
Matched Description: … (S)-propane-1,2-diol is a clear, colorless, viscous organic solvent and diluent used in pharmaceutical …
DIETHYL PROPANE-1,3-DIYLBISCARBAMATE
Experimental
Matched Name: … DIETHYL PROPANE-1,3-DIYLBISCARBAMATE …
Valopicitabine
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Leupeptin
Investigational
Matched Synonyms: … Acetyl-leucyl-leucyl-argininal ... Acetyl-l-leucyl-l-leucyl-l-argininal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID
Experimental
Matched Name: … N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID …
Procyclidine
A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Approved
Matched International brands: … Prodine …
Matched Description: … extrapyramidal disorders and in parkinsonism. ... A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced …
Matched Description: … extrapyramidal disorders and in parkinsonism. ... A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced …
Olanzapine
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Description: … and the absence of a chloride moiety. ... [A176996] The second-generation antipsychotics were introduced in the 90s and quickly gained traction ... due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H2 Antagonists …
Matched Products: … PROLANZ® 5 MG ... PROLANZ 10 MG ... PROLANZ ® 10MG …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H2 Antagonists …
Matched Products: … PROLANZ® 5 MG ... PROLANZ 10 MG ... PROLANZ ® 10MG …
Etoricoxib
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … PROKIN-X. ... PROKIN-X® ... PROKIN-X. 120 …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … PROKIN-X. ... PROKIN-X® ... PROKIN-X. 120 …
Displaying drugs 726 - 750 of 923 in total