Displaying drugs 1051 - 1075 of 1360 in total
Viral Macrophage-Inflammatory Protein
Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer under most conditions. It helps its virus evade the host immune system through selectively blocking and activating different receptors, preferentially...
Investigational
Matched Synonyms: … Viral Macrophage Inflammatory Protein-II …
Matched Name: … Viral Macrophage-Inflammatory Protein …
Matched Description: … Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog ... The structure of vMIP consists of 71 residues and is a monomer under most conditions. ... It helps its virus evade the host immune system through selectively blocking and activating different …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Matched Name: … Viral Macrophage-Inflammatory Protein …
Matched Description: … Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog ... The structure of vMIP consists of 71 residues and is a monomer under most conditions. ... It helps its virus evade the host immune system through selectively blocking and activating different …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins …
Efavaleukin alfa
Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … Fc il-2 mutein fusion protein (amg-592) ... protein with interleukin 2 (synthetic human mutein), dimer ... Immunoglobulin g1 (fc domain-containing fragment) fusion protein with peptide (synthetic linker) fusion …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With ... Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With ... Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin …
(2R,3R,4R,5R)-3,4-Dihydroxy-N,N'-bis[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2,5-bis(2-phenylethyl)hexanediamide
Experimental
Matched Synonyms: … Diol-Based HIV-1 protease inhibitor 4 …
Recombinant stabilized RSV A prefusion F antigen
Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Synonyms: … RSV subgroup A stabilized prefusion F protein …
Matched Description: … then purified and lyophilized. ... stabilized RSV A prefusion F antigen] - which have been expressed in Chinese hamster ovary cell lines and ... virus vaccine, adjuvanted] (Arexvy), Abrysvo is reconstituted with sterile water prior to injection and …
Matched Description: … then purified and lyophilized. ... stabilized RSV A prefusion F antigen] - which have been expressed in Chinese hamster ovary cell lines and ... virus vaccine, adjuvanted] (Arexvy), Abrysvo is reconstituted with sterile water prior to injection and …
Influenza A virus subtype H1N1 haemagglutinin, recombinant
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain A (H1N1) …
Influenza B virus Victoria lineage haemagglutinin, recombinant
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain B (Victoria) …
Oxtriphylline
Oxtriphylline is the choline salt form of theophylline. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Its main physiological reponse is to dilate the bronchioles. As such, oxytriphylline is indicated mainly for asthma, bronchospasm, and COPD (i.e. all...
Approved
Matched Synonyms: … Teofilinato de colina …
Matched Description: … blocker, and histone deacetylase activator. ... Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor ... As such, oxytriphylline is indicated mainly for asthma, bronchospasm, and COPD (i.e. all the same indications …
Matched Categories: … Xanthines and Adrenergics ... choline theophyllinate and adrenergics …
Matched Description: … blocker, and histone deacetylase activator. ... Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor ... As such, oxytriphylline is indicated mainly for asthma, bronchospasm, and COPD (i.e. all the same indications …
Matched Categories: … Xanthines and Adrenergics ... choline theophyllinate and adrenergics …
(3,4,8b-Trimethyl-3-oxido-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-3-ium-7-yl) N-(2-ethylphenyl)carbamate
Experimental
Matched Name: … (3,4,8b-Trimethyl-3-oxido-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-3-ium-7-yl) N-(2-ethylphenyl)carbamate …
EDI-200
EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
Investigational
Matched Synonyms: … FC:EDA-A1 FUSION PROTEIN ... HUMAN IMMUNOGLOBULIN G1 CONSTANT REGION - HUMAN ECTODYSPLASIN-A1 RECEPTOR-BINDING DOMAIN FUSION PROTEIN …
Matched Description: … EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Blood Proteins ... Membrane Proteins …
Matched Description: … EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Blood Proteins ... Membrane Proteins …
SAR-439459
SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody. Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis Imperfecta.
Investigational
Matched Synonyms: … ANTI-TGF-BETA MONOCLONAL ANTIBODY SAR-439459 …
Matched Description: … [A259862] Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis ... SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody. …
Matched Description: … [A259862] Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis ... SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody. …
RC118
RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.
Investigational
Matched Synonyms: … Recombinant humanized anti-MSLN monoclonal antibody- monomethyl auristatin E conjugate …
Matched Description: … antibody conjugated to MMAE. ... RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal …
Matched Description: … antibody conjugated to MMAE. ... RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal …
Ontamalimab
Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational
Matched Synonyms: … human IgG2 monoclonal antibody directed against the mucosal addressin cell adhesion molecule ... human IgG2 anti-monoclonal antibody directed against mucosal addressin cell adhesion molecule (MAdCAM …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Parathyroid Hormone-Related Protein 1-36
Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and PTH to Treat Osteoporosis).
Investigational
Matched Synonyms: … Parathyroid hormone-related protein 1-36 ... Parathyroid hormone related protein(1-36) ... Parathyroid hormone related protein (1-36) …
Matched Name: … Parathyroid Hormone-Related Protein 1-36 …
Matched Description: … Study of Pthrp and PTH to Treat Osteoporosis). ... Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins …
Matched Name: … Parathyroid Hormone-Related Protein 1-36 …
Matched Description: … Study of Pthrp and PTH to Treat Osteoporosis). ... Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins …
Losartan
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored …
Matched Mixtures name: … Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... losartan and diuretics ... losartan and amlodipine …
Matched Products: … COLIBS ... COZAAR PROTECT 50MG ... LORZAAR PROTECT 50MG …
Matched Mixtures name: … Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... losartan and diuretics ... losartan and amlodipine …
Matched Products: … COLIBS ... COZAAR PROTECT 50MG ... LORZAAR PROTECT 50MG …
Pabinafusp alfa
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … Immunoglobulin G1-kappa, anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused ... WITH PEPTIDE (SYNTHETIC 2-AMINO ACID LINKER) FUSION PROTEIN WITH HUMAN IDURONATE-2-SULFATASE, DISULFIDE ... G1, ANTI-(HUMAN TRANSFERRIN RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JR-141 .GAMMA.1-CHAIN) FUSION PROTEIN …
SBT-100
SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody (sdAb). It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma.[L44131,L44136]
Investigational
Matched Synonyms: … Anti-STAT3 B VHH13 single domain antibody …
Matched Description: … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody ... It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma …
Matched Description: … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody ... It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma …
RLYB212
RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Investigational
Matched Synonyms: … Recombinant human IgG monoclonal HPA-1a antibody …
Matched Description: … It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia ... RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). …
Matched Description: … It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia ... RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). …
Anetumab ravtansine
Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Anti-mesothelin antibody-drug conjugate BAY 94-9343 …
Matched Description: … Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates ... Proteins ... Blood Proteins …
Matched Description: … Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates ... Proteins ... Blood Proteins …
CMG901
CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload.
Investigational
Matched Synonyms: … an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload …
Matched Description: … CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload. …
Matched Description: … CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload. …
Simlukafusp alfa
RO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic Cancer)).
Investigational
Matched Synonyms: … Anti-fap/interleukin-2 fusion protein ro6874281 …
Gontivimab
Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV) Infection).
Investigational
Matched Synonyms: … Anti-rsv protein f nanobody alx-0171 …
Matched Description: … Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Indigotindisulfonic acid
Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in the production of food colorants and pH tests. Indigotindisulfonic acid is used in...
Approved
Investigational
Matched Description: … This compound is an acid-base indicator and is used in the production of food colorants and pH tests. ... Indigotindisulfonic acid is used in clinical medicine to determine patency of the urinary collecting system, and ... [A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine …
Matched Salts name: … Indigotindisulfonate sodium …
Matched Categories: … Tests for Renal Function and Ureteral Injuries …
Matched Products: … SODIO INDIGOTINDISOLFONATO S.A.L.F. ... SODIO INDIGOTINDISULFONATO MONICO …
Matched Salts name: … Indigotindisulfonate sodium …
Matched Categories: … Tests for Renal Function and Ureteral Injuries …
Matched Products: … SODIO INDIGOTINDISOLFONATO S.A.L.F. ... SODIO INDIGOTINDISULFONATO MONICO …
Alpha-1-proteinase inhibitor
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … .-1 protease inhibitor ... Protease inhibitor wap4 ... Alpha-1 protease inhibitor …
Matched Description: … inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and ... zinc chloride fractionation. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Matched Description: … inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and ... zinc chloride fractionation. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Satralizumab
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Synonyms: … Humanised anti-IL-6 receptor monoclonal antibody …
Matched Description: … 6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on ... [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... central nervous system (CNS) involving demyelinating lesions in the optic nerve, spinal cord, brainstem, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins ... Blood Proteins …
Matched Description: … 6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on ... [A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use ... central nervous system (CNS) involving demyelinating lesions in the optic nerve, spinal cord, brainstem, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins ... Blood Proteins …
Displaying drugs 1051 - 1075 of 1360 in total