Displaying drugs 2051 - 2075 of 2319 in total
IMCY-0141
IMCY-0141 is a synthetic peptide based on MOG (Myelin Oligodendrocyte Glycoprotein), a dominant autoantigen, designed to stop the progression of multiple sclerosis (MS) and the destruction of the myelin sheath protecting the nerves.
Investigational
Matched Description: … IMCY-0141 is a synthetic peptide based on MOG (Myelin Oligodendrocyte Glycoprotein), a dominant autoantigen …
Sulfotep
Experimental
Vet approved
LB-001
LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA mutase (MUT) gene into the genome of patients with methylmalonic acidemia.
Investigational
Matched Description: … LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA …
Lanoteplase
Investigational
SOBI-003
SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients).
Investigational
Matched Description: … SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. ... It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, …
MCC
Mycobacterial Cell Wall-DNA Complex (MCC) is formulated from Mycobacterium phlei, a non-pathogenic strain of mycobacteria. MCC has been shown to have immune stimulatory and apoptosis (programmed cell death) activity against cancer cells. The product is a sterile biological composition in a sub-micron suspension. It is produced at the Bioniche manufacturing...
Investigational
Matched Description: … The product is a sterile biological composition in a sub-micron suspension. ... Mycobacterial Cell Wall-DNA Complex (MCC) is formulated from Mycobacterium phlei, a non-pathogenic strain …
TRC093
TRC093 is a recombinant humanized IgG1k monoclonal antibody.
Investigational
Matched Description: … TRC093 is a recombinant humanized IgG1k monoclonal antibody. …
Maveropepimut-S
Maveropepimut-S is a T cell activating immunotherapy.
Investigational
Matched Description: … Maveropepimut-S is a T cell activating immunotherapy. …
CTA018
CTA018 is a member of a new class of vitamin D analogues with a dual mechanism of action, called Vitamin D Signal Amplifiers. This proprietary new drug is both a potent inhibitor of CYP24 (the enzyme responsible for the breakdown of vitamin D) and a potent activator of vitamin D...
Investigational
Matched Description: … CTA018 is a member of a new class of vitamin D analogues with a dual mechanism of action, called Vitamin ... of vitamin D) and a potent activator of vitamin D signaling pathways. ... This proprietary new drug is both a potent inhibitor of CYP24 (the enzyme responsible for the breakdown …
Bromelains
Bromelain is a protease enzyme derived from the stems of pineapples that is composed of a mixture of different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase, cellulase, escharase, and several protease inhibitors . It works by selectively inhibiting the biosynthesis of proinflammatory prostaglandins and also has analgesic properties,...
Investigational
Matched Description: … Bromelain is a protease enzyme derived from the stems of pineapples that is composed of a mixture of ... It is considered as a safe food supplement. ... Bromelain holds potential therapeutic effect as a treatment of conditions including angina pectoris, …
Neocartilage
Neocartilage, a novel cartilage regeneration treatment. Neocartilage is generated from juvenile rather than adult chondrocytes. Neocartilage is the only scaffold-free living cartilage graft on the market.
Investigational
Matched Description: … Neocartilage, a novel cartilage regeneration treatment. …
Barbital
A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice for central nervous system depression. Barbital is a schedule IV controlled drug.
Illicit
Matched Description: … Barbital is a schedule IV controlled drug. ... It is used as a hypnotic and sedative and may induce dependence. ... A long-acting barbiturate that depresses most metabolic processes at high doses. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pentaglobin
Pentaglobin, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin preparations. It is comprised of immunoglobulin G (IgG) (https://www.drugbank.ca/drugs/DB00028) and immunoglobulin A (IgA) while also being enriched by immunoglobulin M (IgM).
Investigational
Matched Description: … Pentaglobin, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin ... is comprised of [immunoglobulin G (IgG)](https://www.drugbank.ca/drugs/DB00028) and immunoglobulin A …
PBKR03
PBKR03 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, containing a transgene encoding the human galactosylceramidase (GALC) enzyme.
Investigational
Matched Description: … PBKR03 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, containing a transgene …
N,N,N-trimethylglycinium
A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for...
Experimental
Investigational
Matched Description: … As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria ... A naturally occurring compound that has been of interest for its role in osmoregulation. …
Vibriolysin
Vibriolysin is a proteolytic enzyme secreted by the marine microorganism Vibrio proteolyticus. It is a new agent for enzymatic debridement, shown to rapidly and thoroughly hydrolyze burn wound eschar within full-thickness wounds.
Investigational
Matched Description: … Vibriolysin is a proteolytic enzyme secreted by the marine microorganism Vibrio proteolyticus. ... It is a new agent for enzymatic debridement, shown to rapidly and thoroughly hydrolyze burn wound eschar …
Eldelumab
MDX-1100, a fully human antibody that targets IP10 (also known as CXCL10), a chemokine expressed in association with multiple inflammatory disease indications, such as rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis.
Investigational
Matched Description: … MDX-1100, a fully human antibody that targets IP10 (also known as CXCL10), a chemokine expressed in association …
Collagen-polyvinylpyrrolidone
Collagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight PVP that has undergone γ irradiation . It is characterized by antifibrotic, fibrolytic, and immunomodulatory properties .
Investigational
Matched Description: … Collagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
DR-01
DR-01 is a monoclonal antibody directed against human CD94.
Investigational
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …
LTI-03
LTI-03 is a caveolin-1 Scaffolding Domain 7-Mer
Investigational
Matched Description: … LTI-03 is a caveolin-1 Scaffolding Domain 7-Mer …
PRO-542
PRO 542 belongs to a new class of drugs, viral-entry inhibitor, which is intended to prevent HIV from entering and infecting cells. PRO 542 (CD4-immunoglobulin G2) is a tetravalent CD4-immunoglobulin fusion protein that broadly neutralizes primary HIV-1 isolates.
Investigational
Matched Description: … primary HIV-1 isolates. ... PRO 542 belongs to a new class of drugs, viral-entry inhibitor, which is intended to prevent HIV from ... PRO 542 (CD4-immunoglobulin G2) is a tetravalent CD4-immunoglobulin fusion protein that broadly neutralizes …
Matched Categories: … HIV-1 …
Matched Categories: … HIV-1 …
CCR5 mAb
CCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus (HIV-1). It was generated by HGS using the Abgenix XenoMouse technology.
Investigational
Matched Description: … CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus (HIV-1). ... CCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor …
Zilovertamab vedotin
Zilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker (mc-vc-PAB), and a monomethyl auristatin E (MMAE) cytotoxin.
Investigational
Matched Description: … proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker (mc-vc-PAB), and a ... Zilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a …
Sophora flavescens root
Experimental
Neramexane
Neramexane is a low-to-moderate affinity uncompetitive NMDA receptor antagonist.
Investigational
Matched Iupac: … 1,3,3,5,5-pentamethylcyclohexan-1-amine …
Matched Description: … Neramexane is a low-to-moderate affinity uncompetitive NMDA receptor antagonist. …
Matched Description: … Neramexane is a low-to-moderate affinity uncompetitive NMDA receptor antagonist. …
Displaying drugs 2051 - 2075 of 2319 in total