Displaying drugs 2426 - 2450 of 3059 in total
Encaleret
Investigational
Matched Synonyms: … (1,1'-biphenyl)-4-carboxylic acid, 2'-((1r)-1-((2r)-3-((2-(4-chloro-3-fluorophenyl)-1,1-dimethylethyl ... fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)ethyl)-3-methyl(1,1'-biphenyl)-4-carboxylic acid ... fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropyl)oxy)ethyl)-3-methyl-1,1'-biphenyl-4-carboxylic acid …
Matched Iupac: … fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3-methyl-[1,1'-biphenyl]-4-carboxylic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3-methyl-[1,1'-biphenyl]-4-carboxylic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Ropinirole
Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first...
Approved
Investigational
Matched Description: … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and ... capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and ... offering a similar side effect profile and efficacy to previous formulations of ropinirole [A35711]. …
Matched Products: … ROPINIROL ACIS 2MG …
Matched Products: … ROPINIROL ACIS 2MG …
Amoxicillin
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Synonyms: … 6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid ... -2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … CLAVAM INJECTION 1.2g ... Amoxicillin Sodium and Potassium Clavulanate for Injection ... Amoxicillin Sodium and Potassium Clavulanate for Injection …
Matched Salts name: … Amoxicillin sodium …
Matched Categories: … Sulfur Compounds ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... rabeprazole, amoxicillin and clarithromycin …
Matched Products: … AMOXICILLIN SODIUM ... AMOXICILLINA E ACIDO CLAVULANICO PFIZER ... AMOXICILLINA SODICA K24 PHARMACEUTICALS …
Matched Iupac: … amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … CLAVAM INJECTION 1.2g ... Amoxicillin Sodium and Potassium Clavulanate for Injection ... Amoxicillin Sodium and Potassium Clavulanate for Injection …
Matched Salts name: … Amoxicillin sodium …
Matched Categories: … Sulfur Compounds ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... rabeprazole, amoxicillin and clarithromycin …
Matched Products: … AMOXICILLIN SODIUM ... AMOXICILLINA E ACIDO CLAVULANICO PFIZER ... AMOXICILLINA SODICA K24 PHARMACEUTICALS …
Rodatristat
Investigational
Matched Synonyms: … chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)-4-pyrimidinyl)-2,8-diazaspiro(4.5)decane-3-carboxylic acid ... 2,8-diazaspiro(4.5)decane-3-carboxylic acid, 8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2 ... chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro(4.5)decane-3-carboxylic acid …
Matched Iupac: … -[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid …
Matched Iupac: … -[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl}-2,8-diazaspiro[4.5]decane-3-carboxylic acid …
Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Experimental
Matched Name: … Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamate …
Matched Iupac: … benzyl N-[(1S)-4-[(diaminomethyl)amino]-1-{[(2S)-4-fluoro-3-oxobutan-2-yl]carbamoyl}butyl]carbamate …
Matched Iupac: … benzyl N-[(1S)-4-[(diaminomethyl)amino]-1-{[(2S)-4-fluoro-3-oxobutan-2-yl]carbamoyl}butyl]carbamate …
6-hydroxydopa quinone
Experimental
Matched Synonyms: … Topa quinone ... (S)-α-amino-4-hydroxy-3,6-dioxo-1,4-cyclohexadiene-1-propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … and sodium ions across cell membranes of the lungs, pancreas, and other organs. ... with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... Transmembrane Conductance Regulator (CFTR) protein, a transmembrane ion channel involved in the transport of chloride …
Matched Categories: … ivacaftor and lumacaftor …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … and sodium ions across cell membranes of the lungs, pancreas, and other organs. ... with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... Transmembrane Conductance Regulator (CFTR) protein, a transmembrane ion channel involved in the transport of chloride …
Matched Categories: … ivacaftor and lumacaftor …
tert-butyl [(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]carbamate
Experimental
Matched Name: … tert-butyl [(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]carbamate …
Matched Iupac: … tert-butyl N-({2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}methyl)carbamate …
Matched Iupac: … tert-butyl N-({2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}methyl)carbamate …
Iloprost
Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47. It is a potent vasodilator with reported...
Approved
Investigational
Matched Synonyms: … Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid ... PENTANOIC ACID, 5-((3AS,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-((1E,3S)-3-HYDROXY-4-METHYL-1-OCTEN-6-YNYL)- ... )-hexahydro-5-hydroxy-4-[(E)-(3S,4RS) 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H),Δ-pentalenevaleric acid …
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid …
Matched Description: … [A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately ... [A263316] Iloprost is available as an inhaled solution and intravenous formulations. ... It is used to treat pulmonary arterial hypertension (PAH) [L50146] and frostbites.[L50151] …
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated …
Matched Iupac: … 6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid …
Matched Description: … [A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately ... [A263316] Iloprost is available as an inhaled solution and intravenous formulations. ... It is used to treat pulmonary arterial hypertension (PAH) [L50146] and frostbites.[L50151] …
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated …
Udonitrectag
Investigational
Matched Synonyms: … (1s,4r,5r,7s)-3, 4-dibenzyl-2-oxo-6, 8-dioxa-3-azabicyclo (3.2.1) octane-7-carboxylic acid ... 3, 4-dibenzyl-2-oxo-6, 8-dioxa-3-azabicyclo (3.2.1) octane-7-carboxylic acid, (1s,4r,5r,7s)- ... 6,8-dioxa-3-azabicyclo(3.2.1)octane-7-carboxylic acid, 2-oxo-3,4-bis(phenylmethyl)-, (1s,4r,5r,7s)- …
Matched Iupac: … (1S,4R,5R,7S)-3,4-dibenzyl-2-oxo-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-carboxylic acid …
Matched Iupac: … (1S,4R,5R,7S)-3,4-dibenzyl-2-oxo-6,8-dioxa-3-azabicyclo[3.2.1]octane-7-carboxylic acid …
3-[2,6,8-Trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate
Experimental
Matched Name: … 3-[2,6,8-Trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate …
Matched Iupac: … acid ... {2,6,8-trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2,3,6,7,8,9-hexahydro-1H-purin-7-yl}propoxy)phosphonic …
Matched Iupac: … acid ... {2,6,8-trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2,3,6,7,8,9-hexahydro-1H-purin-7-yl}propoxy)phosphonic …
3-[2,6,8-Trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate
Experimental
Matched Name: … 3-[2,6,8-Trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate …
Matched Iupac: … acid ... {2,6,8-trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-2,3,6,7,8,9-hexahydro-1H-purin-7-yl}propoxy)phosphonic …
Matched Iupac: … acid ... {2,6,8-trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-2,3,6,7,8,9-hexahydro-1H-purin-7-yl}propoxy)phosphonic …
Daglutril
Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart failure.
Investigational
Matched Synonyms: … Ethoxycarbonyl-4-phenylbutyl)cyclopentanecarboxamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)acetic acid …
Matched Iupac: … oxo-2-(2-phenylethyl)propyl]cyclopentaneamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid …
Matched Description: … endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and …
Matched Iupac: … oxo-2-(2-phenylethyl)propyl]cyclopentaneamido}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid …
Matched Description: … endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and …
PTX-100
Investigational
Matched Synonyms: … 2-benzyl-4-(5-methyl-3H-imidazol-4-ylmethyl)-3-oxo-piperazine-1-carbonyl]- amino}-4methyl-pentanoic acid …
Matched Iupac: … -2-benzyl-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxopiperazine-1-carbonyl]amino}-4-methylpentanoic acid …
Matched Iupac: … -2-benzyl-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxopiperazine-1-carbonyl]amino}-4-methylpentanoic acid …
Eluxadoline
Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system. Agonism of peripheral...
Approved
Investigational
Matched Synonyms: … 2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acid …
Matched Iupac: … 2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido]methyl}-2-methoxybenzoic acid …
Matched Description: … Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid ... The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central ... nervous system and peripherally in the gastrointestinal system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … 2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido]methyl}-2-methoxybenzoic acid …
Matched Description: … Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid ... The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central ... nervous system and peripherally in the gastrointestinal system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Guaiacol
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Synonyms: … Pyroguaiac acid …
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. …
Matched Salts name: … Guaiacol carbonate …
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. …
Matched Salts name: … Guaiacol carbonate …
Gemfibrozil
Gemfibrozil is a fibric acid agent, similar to clofibrate, used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. Gemfibrozil was granted FDA approval on 21...
Approved
Matched Synonyms: … 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid …
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... responded adequately to weight loss, diet, exercise, and other medications. ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids …
Matched Iupac: … 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... responded adequately to weight loss, diet, exercise, and other medications. ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids …
BMS-986278
Investigational
Matched Synonyms: … methyl(propyl)carbamoyl)oxy)methyl)-1h-1,2,3-triazol-4-yl)pyridin-3-yl)oxy)cyclohexane-1-carboxylic acid ... Cyclohexanecarboxylic acid, 3-((2-methyl-6-(1-methyl-5-((((methylpropylamino)carbonyl)oxy)methyl)-1h- …
Matched Iupac: … methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acid …
Matched Iupac: … methyl(propyl)carbamoyl]oxy}methyl)-1H-1,2,3-triazol-4-yl]pyridin-3-yl}oxy)cyclohexane-1-carboxylic acid …
JS-K
Investigational
Matched Synonyms: … 1-piperazinecarboxylic acid, 4-((2,4-dinitrophenoxy)-nno-azoxy)-, ethyl ester ... 1-piperazinecarboxylic acid, 4-(2-(2,4-dinitrophenoxy)-1-oxidodiazenyl)-, ethyl ester …
Immucin
Investigational
Matched Synonyms: … Synthetic Signal Peptide Of Human Mucin-1 (Amino Acids 1-21) …
Sulfanilamide
Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Approved
Matched Synonyms: … 4-aminobenzene sulfonic acid amide …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Sulfonamides and trimethoprim …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Sulfonamides and trimethoprim …
Zinc phenolsulfonate
Approved
Experimental
Matched Synonyms: … p-hydroxybenzenesulfonic acid zinc salt …
Pyrazinamide
A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational
Matched Synonyms: … Pyrazinoic acid amide …
Matched Categories: … rifampicin, pyrazinamide and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Matched Categories: … rifampicin, pyrazinamide and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
(2R,4S)-2-[(1R)-1-{[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
Experimental
Matched Synonyms: … 2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Name: … 2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Iupac: … -[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Name: … 2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Iupac: … -[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Displaying drugs 2426 - 2450 of 3059 in total