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Displaying drugs 2476 - 2500 of 6179 in total

3,5-Dihydro-5-Methylidene-4h-Imidazol-4-On

Experimental
Matched Name: … 3,5-Dihydro-5-Methylidene-4h-Imidazol-4-On …
Matched Iupac: … 2-[(2S,4S)-2-[(1S)-1-aminoethyl]-4-(aminomethyl)-5-oxoimidazolidin-1-yl]acetic acid …

2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID

Experimental
Matched Name: … 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC …
Matched Iupac: … (2S)-2-{[4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-3-methylbutanoic …

Alphameprodine

Alphameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer betameprodine is similarly classified, however alphameprodine is more widely used (both are referred to as Meprodine). Alphameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of...
Experimental
Illicit
Matched Synonyms: … alpha-3-ethyl-1-methyl-4-phenyl-4-propionoxypiperidine ... alpha-3-Ethyl-1-methyl-4-phenyl-4-propionyloxypiperidine ... 3alpha-Ethyl-1-methyl-4-phenyl-4alpha-piperidyl propionat …
Matched Iupac: … (3S,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate …

SEL-24

Investigational
Matched Synonyms: … 1h-benzimidazole, 5,6-dibromo-1-(1-methylethyl)-4-nitro-2-(4-piperidinyl)- ... 5,6-dibromo-1-(1-methylethyl)-4-nitro-2-(4-piperidinyl)-1h-benzimidazole ... 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1h-1,3-benzimidazole …
Matched Iupac: … 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1H-1,3-benzodiazole …

JQ1

First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Synonyms: … (s)-(+)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin ... 6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl ... Tert-butyl 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin …
Matched Iupac: … tert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6 …

SB-269970

SB-269970 is an experimental drug developed by GlaxoSmithKline. In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5-HT7).[A31816,A31817]
Investigational
Matched Iupac: … 3-{[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonyl}phenol …
Matched Description: … suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 …

Bilh 434

Experimental
Matched Iupac: … (2R,3'R,4'S,5'R)-5'-(3,4-dichlorophenyl)-6-methyl-1,3-dioxo-4'-{[4-(1,2,3-thiadiazol-4-yl)phenyl]carbamoyl …

AVI-4557

AVI-4557 is an oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver enzyme responsible for the metabolism or breakdown of approximately half of currently marketed drugs. Studies indicate that AVI-4557 can successfully reduce the rate of metabolism for certain drugs, therefore allowing greater and...
Investigational

R411

R411 is a non-steroid oral medicine for the treatment of asthma. It is not immunosuppressive, but blocks the activation and recruitment of cells involved in respiratory inflammation. It is a dual-acting competitive integrin antagonist (as compared to previously developed single integrin antagonists or SIAs) that prevents binding of V-CAM1 to...
Investigational

R450

R450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. It is being considered for treatment of stress-related urinary incontinence. Phase IIa data for the drug show it reduced the number of incontinent episodes compared to placebo with minimal cardiovascular effects.
Investigational

T487

T487 is a small molecule chemokine receptor antagonist to correct or modify immune system responses. It binds selectively and potently to CXCR3. The formulation is administered orally and has anti-inflammatory effects in conditions such as rheumatoid arthritis, inflammatory bowel disease and psoriasis.
Investigational

PLX-4720

Experimental

AZD-4877

AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others.
Investigational
Matched Iupac: … )-4-methylbenzamide ... N-(3-aminopropyl)-N-(1-{5-benzyl-3-methyl-4-oxo-4H,5H-[1,2]thiazolo[5,4-d]pyrimidin-6-yl}-2-methylpropyl …

INO-4995

INO-4995 is an inositol tetrakisphosphate analog being investigated for Cystic Fibrosis.
Investigational

INT41

INT41 (also known as rAAV6-INT41) is a recombinant adeno-associated virus vector containing DNA encoding INT41 intrabody.
Investigational

AGTC-401

AGTC-401 is a recombinant adeno-associated virus vector expressing the cyclic nucleotide gated channel beta subunit (rAAV-CNGB3).
Investigational

TPX-4589

TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational

CFT-8634

Investigational
Matched Synonyms: … 2,6-PIPERIDINEDIONE, 3-((4-(4-((4S)-1-((4-(1,6-DIHYDRO-1,4,5-TRIMETHYL-6-OXO-3-PYRIDINYL)-2,6-DIMETHOXYPHENYL ... )METHYL)-3,3-DIFLUORO-4-PIPERIDINYL)-1-PIPERAZINYL)-3-FLUOROPHENYL)AMINO)-, (3S)- …
Matched Iupac: … (3S)-3-[(4-{4-[(4S)-1-{[2,6-dimethoxy-4-(1,4,5-trimethyl-6-oxo-1,6-dihydropyridin-3-yl)phenyl]methyl} ... -3,3-difluoropiperidin-4-yl]piperazin-1-yl}-3-fluorophenyl)amino]piperidine-2,6-dione …

4-Carboxy-4-Aminobutanal

Experimental
Matched Name: … 4-Carboxy-4-Aminobutanal …

TAS-106

TAS-106 is a new nucleoside antimetabolite. TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours .
Investigational
Matched Synonyms: … 4-Amino-1-((2R,3R,4R,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one …
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2 …

Izaflortaucipir

Investigational
Matched Synonyms: … 9h-pyrido(3',4':4,5)pyrrolo(2,3-b)pyridine, 2-(2-fluoro-4-pyridinyl)- ... 2-(2-fluoropyridin-4-yl)-9h-pyrrolo(2,3-b:4,5-c')dipyridine …
Matched Iupac: … 11-(2-fluoropyridin-4-yl)-4,8,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene …

TAK-071

TAK-071 is under investigation in clinical trial NCT04334317 (A Study of TAK-071 in People With Parkinson Disease).
Investigational
Matched Synonyms: … 4-fluoro-2-((3s, 4s)-4-hydroxytetrahydro-2h-pyran-3-yl)-5-methyl-6-(4(1h-pyrazol-1-yl)benzyl)-2, 3-dihydro …

N4-Hydroxycytidine

N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Synonyms: … 4-N-Hydroxycytidine ... Uridine, 4-oxime ... N(4)-Hydroxycytidine …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)-1,2-dihydropyrimidin-2- …

BMS-770767

BMS-770767 is under investigation in clinical trial NCT01058083 (Safety Study of BMS-770767 in Subjects With Hypercholesterolemia).
Investigational
Matched Synonyms: … 4-(8-(2-CHLOROPHENOXY)(1,2,4)TRIAZOLO(4,3-A)PYRIDIN-3-YL)BICYCLO(2.2.1)HEPTAN-1-OL ... BICYCLO(2.2.1)HEPTAN-1-OL, 4-(8-(2-CHLOROPHENOXY)-1,2,4-TRIAZOLO(4,3-A)PYRIDIN-3-YL)- …

4-O-Demethylpenclomedine

Investigational
Matched Synonyms: … 4-Dmpen ... 4-Dm-pen ... 4-Demethylpenclomedine …
Matched Name: … 4-O-Demethylpenclomedine …
Matched Iupac: … 3,5-dichloro-2-methoxy-6-(trichloromethyl)-1,4-dihydropyridin-4-one …
Displaying drugs 2476 - 2500 of 6179 in total