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Displaying drugs 2551 - 2575 of 3166 in total
EGS21
EGS21(TM) is a beta-D-glucosylceramide (GC) compound. It is a potential therapeutic for treating immune mediated disorders. GC is a glycolipid that has been shown by Enzo scientists and collaborators to act as an anti-inflammatory agent in animal model systems, and therefore is being evaluated as an important candidate drug in...
Investigational
Matched Description: … GC is a glycolipid that has been shown by Enzo scientists and collaborators to act as an anti-inflammatory …
Allogeneic Cardiosphere-Derived Cells
Cardiosphere-derived cells (CDCs) are derived from human neonatal heart tissue with a distinct antigenic profile (CD105+, CD45-, and CD90low). They exert their effects by secreting exosomes: nanometer-sized, membrane-bound vesicles used for the purpose of cell-cell communication. CDCs target multiple cytokine pathways associated with poor outcomes (e.g. TNFa, IFN-y, IL-1B, and...
Investigational
Matched Description: … The anti-inflammatory effects of CDC work through polarizing macrophages and restoring tissue function …
Murepavadin
Murepavadin is under investigation in clinical trial NCT02110459 (Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment).
Investigational
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Anisomycin
Anisomycin (sometimes known as flagecidin), is an antibiotic retrieved from the bacteria Streptomyces griseolus. This drug acts to inhibit bacterial protein and DNA synthesis.
Experimental
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Emivirine
Emivirine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Categories: … Anti-Infective Agents ... Anti-Retroviral Agents …
LFF-571
LFF571 has been used in trials studying the treatment of Moderate Clostridium Difficile Infection.
Investigational
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Cefetamet pivoxil
Cefetamet pivoxil is under investigation in clinical trial NCT04664803 (Safety and Efficacy of Cefecin Tab. in Patients With Acute Sinusitis).
Investigational
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Fepradinol
Experimental
Matched Categories: … Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal …
MDX-018
MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation. Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system. Other possible indications include chronic obstructive pulmonary disease (COPD)...
Investigational
Irofulven
A novel anti-cancer compound synthesized by scientists at the University of California, San Diego more than a decade ago from toxins of the poisonous jack-o-lantern mushroom, has been granted “fast track” status by the U.S. Food and Drug Administration (FDA) after demonstrating promise against one of the most deadly cancers....
Investigational
Matched Description: … A novel anti-cancer compound synthesized by scientists at the University of California, San Diego more …
Bardoxolone methyl
Investigational
FM-VP4
FM-VP4, is a novel hydrophilic phytostanol analogue representing a new class in cholesterol-lowering drugs called cholesterol absorption inhibitors. FM-VP4 has been shown to inhibit cholesterol absorption and to lower plasma LDL-cholesterol and total cholesterol in a broad range of animal species. Additional experiments suggest that FM-VP4 can reduce plasma LDL...
Investigational
Matched Description: … FM-VP4 can reduce plasma LDL cholesterol levels and triglyceride levels, reduce weight gain and exert a anti-atherosclerosis …
XMT-1001
XMT-1001 is a polymer-based prodrug of camptothecin (CPT), a well-characterized topoisomerase I inhibitor with potent anti-tumor activity. It is a water-soluble macromolecular conjugate of camptothecin (CPT). In this novel CPT pro-drug, CPT is conjugated with a 70 kDa biodegradable hydrophilic polyacetal, poly (1-hydroxymethylene hydroxylmethylformal). XMT-1001 has demonstrated an improved therapeutic...
Investigational
Matched Description: … polymer-based prodrug of camptothecin (CPT), a well-characterized topoisomerase I inhibitor with potent anti-tumor …
Troxacitabine
Troxacitabine is a nucleoside analog with antineoplastic activity. There has been growing interest in its development for the treatment of patients with refractory lymphoproliferative conditions.
Investigational
Matched Categories: … Anti-HIV Agents ... Anti-Infective Agents …
UC-781
UC-781 is a thiocarboxanilide non-nucleoside reverse transcriptase inhibitor (NNRTI). It is a topical microbicide targeted against the AIDS virus.
Investigational
Matched Categories: … Anti-Infective Agents ... Anti-Retroviral Agents …
Narasin
Narasin is an agent with coccidiostatic and antibacterial properties.
Experimental
Vet approved
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Nafithromycin
Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP).
Investigational
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Dapansutrile
Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee).
Investigational
Matched Categories: … Anti-Inflammatory Agents …
Bersacapavir
Bersacapavir is under investigation in clinical trial NCT03365947 (Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)).
Investigational
Matched Categories: … Anti-Infective Agents …
Displaying drugs 2551 - 2575 of 3166 in total