Displaying drugs 2626 - 2650 of 7327 in total
rAAV9-rsATP7A
A recombinant adeno-associated viral vector gene therapy under investigation for the treatment of Menkes disease.
Investigational
(5S)-2-{[(1S)-1-(4-Fluorophenyl)ethyl]amino}-5-(2-hydroxy-2-propanyl)-5-methyl-1,3-thiazol-4(5H)-one
Experimental
Matched Name: … (5S)-2-{[(1S)-1-(4-Fluorophenyl)ethyl]amino}-5-(2-hydroxy-2-propanyl)-5-methyl-1,3-thiazol-4(5H)-one …
Matched Iupac: … (5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(2-hydroxypropan-2-yl)-5-methyl-4,5-dihydro-1,3-thiazol ... -4-one …
Matched Iupac: … (5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(2-hydroxypropan-2-yl)-5-methyl-4,5-dihydro-1,3-thiazol ... -4-one …
Pyridoxal
The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. [PubChem]
Experimental
Nutraceutical
Matched Synonyms: … 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine ... 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde ... 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde …
Matched Iupac: … 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde …
Matched Description: … The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme …
Matched Salts cas: … 65-22-5 …
Matched Iupac: … 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde …
Matched Description: … The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme …
Matched Salts cas: … 65-22-5 …
Tyrphostin B44
Experimental
Udifitimod
Udifitimod is under investigation in clinical trial NCT05014438 (A Study of BMS-986166 or Branebrutinib for the Treatment of Participants With Atopic Dermatitis).
Investigational
Coproporphyrinogen III
Experimental
Matched Iupac: … 21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1(20),3,5,8,10,13,15,18-octaen-4- …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Celastrol
Celastrol is a pentacyclic triterpenoid isolated from the root extracts of Tripterygium wilfordii.
Investigational
(5R)-N,N-DIETHYL-5-METHYL-2-[(THIOPHEN-2-YLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
Experimental
Matched Name: … (5R)-N,N-DIETHYL-5-METHYL-2-[(THIOPHEN-2-YLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE …
Matched Iupac: … (5R)-N,N-diethyl-5-methyl-2-(thiophene-2-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide …
Matched Iupac: … (5R)-N,N-diethyl-5-methyl-2-(thiophene-2-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide …
Navocaftor
Navocaftor is under investigation in clinical trial NCT04853368 (Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/navocaftor/abbv-119 or Galicaftor/navocaftor/abbv-576 Combination Therapies in Adult Participants With Cystic Fibrosis).
Investigational
Matched Synonyms: … (5-(3-amino-5-((4-(trifluoromethoxy)phenyl)sulfonyl)pyridin-2-yl)-1,3,4-oxadiazol-2-yl)methanol ... 1,3,4-oxadiazole-2-methanol, 5-(3-amino-5-((4-(trifluoromethoxy)phenyl)sulfonyl)-2-pyridinyl)- …
5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid
Experimental
Matched Name: … 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid …
Matched Iupac: … 5-[(3-carbamoylphenyl)methyl]-5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-4-carboxylic acid …
Matched Iupac: … 5-[(3-carbamoylphenyl)methyl]-5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-4-carboxylic acid …
5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine
Experimental
Matched Name: … 5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine …
Matched Iupac: … 5-{[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl}pyrimidine-2,4-diamine …
Matched Iupac: … 5-{[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl}pyrimidine-2,4-diamine …
C-(1-hydrogyl-beta-D-glucopyranosyl) formamide
Experimental
RO-5045337
RO-5045337 is under investigation in clinical trial NCT01164033 (A Study of RO5045337 in Patients With Solid Tumors).
Investigational
Matched Iupac: … 1-[(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole ... -1-carbonyl]-4-(3-methanesulfonylpropyl)piperazine …
Magrolimab
Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g4(225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal hu5f9-g4 .gamma.4- …
Sp-722
Experimental
Matched Iupac: … (2S)-2-[(4-{[(2R)-2-carboxypyrrolidin-1-yl]sulfonyl}phenyl)formamido]pentanedioic acid …
CX-717
CX-717 is an ampakine compound previously investigated for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and Alzheimer's disease.
Illicit
Investigational
Matched Iupac: … 5-(morpholine-4-carbonyl)-2,1,3-benzoxadiazole …
BG-777
BG-777 is an immunomodulator with proven efficacy against viral and bacterial infections in preclinical studies.
Investigational
GET-73
Get 73 has been investigated for the treatment of Alcohol Dependence.
Investigational
Matched Iupac: … 4-methoxy-N-{[4-(trifluoromethyl)phenyl]methyl}butanamide …
PIK-75
PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Investigational
Matched Synonyms: … Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazide …
Matched Iupac: … N'-[(E)-{6-bromoimidazo[1,2-a]pyridin-3-yl}methylidene]-N,2-dimethyl-5-nitrobenzene-1-sulfonohydrazide …
Matched Iupac: … N'-[(E)-{6-bromoimidazo[1,2-a]pyridin-3-yl}methylidene]-N,2-dimethyl-5-nitrobenzene-1-sulfonohydrazide …
BQ-788
Investigational
Matched Synonyms: … D-norleucine, n-(((2r,6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)- …
AAV9/MFSD8
AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Description: … It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. …
PD-169316
PD-169316 is a p38 MAP kinase inhibitor.
Investigational
Matched Synonyms: … 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1h-imidazole ... Pyridine, 4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-5-yl)- ... Pyridine, 4-(5-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-4-yl)- …
Matched Iupac: … 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine …
Matched Iupac: … 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine …
(3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine
Experimental
Matched Name: … (3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine …
Matched Iupac: … (3S)-3-propyl-2H,3H-thieno[2,3-f][1,4]oxazepin-5-amine …
Matched Iupac: … (3S)-3-propyl-2H,3H-thieno[2,3-f][1,4]oxazepin-5-amine …
VX-702
VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor. In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Investigational
Displaying drugs 2626 - 2650 of 7327 in total