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Displaying drugs 2651 - 2675 of 7096 in total
Dabocemagene autoficel
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … BULLOSA DERMAL FIBROBLAST CELL FCX-007 INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5' …
Mevalonic acid
Experimental
Matched Synonyms: … (R)-mevalonate ... (R)-mevalonic acid ... (R)-3,5-dihydroxy-3-methylvaleric acid …
5-phospho-D-arabinohydroxamic acid
Experimental
Matched Synonyms: … (2R,3R,4S)-2,3,4-Trihydroxy-5-(hydroxyamino)-5-oxopentyl dihydrogen phosphate …
Matched Name: … 5-phospho-D-arabinohydroxamic acid …
Matched Name: … 5-phospho-D-arabinohydroxamic acid …
(Rp)-cAMPS
Experimental
Matched Synonyms: … (Rp)-adenosine-3',5'-cyclic monophosphorothioate ... adenosine-3',5'-cyclic monophosphorothioate, Rp-isomer …
Matched Iupac: … (2R,4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-sulfanyl-hexahydro-2lambda5-furo[3,2-d][1,3,2 …
Matched Iupac: … (2R,4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-sulfanyl-hexahydro-2lambda5-furo[3,2-d][1,3,2 …
Exbivirumab
Exbivirumab is an investigational monoclonal antibody. It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.
Investigational
Epicatechin
Epicatechin has been used in trials studying the treatment of Pre-diabetes.
Investigational
7,8-dihydroxy-4-phenyl-2H-chromen-2-one
Experimental
Ulevostinag
Investigational
Matched Synonyms: … Guanosine, (p(r))-2'-deoxy-2'-fluoro-5'-o-((r)-hydroxymercaptophosphinyl)-p-thio-.beta. ... Cyclo((p3'r,2's)-2'-deoxy-2'-fluoro-p-thioadenylyl-(3'->5')-(p2'r)- 3'-deoxy-3'-fluoro-p-thioguanylyl ... -(2'->5')) …
R1204
R1204 is G-protein-coupled receptor modulator. It is developed for the treatment of depression.
Investigational
Lipotecan
Investigational
Matched Iupac: … (19S)-8-[(dimethylamino)methyl]-19-ethyl-7-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{ …
Arotinoid acid
Arotinoid acid is a retinoic acid analog which acts as a selective RAR agonist.
Experimental
Berubicin
Investigational
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-(benzyloxy)-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
6S-5,6,7,8-Tetrahydrobiopterin
Experimental
Cyclohexyl-pentyl-maltoside
Experimental
Matched Synonyms: … CYMAL(R)-5 ... CYMAL-5 ... 5-cyclohexyl-1-pentyl-beta-D-maltoside …
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6R)-6-[(5-cyclohexylpentyl)oxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan …
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6R)-6-[(5-cyclohexylpentyl)oxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan …
R673
R673 is a novel NK1 antagonist that penetrates the blood-brain barrier, has excellent safety and tolerability and shows low P450-based drug interaction potential. The phase II program for treatment of depression and anxiety is ongoing in the US and EU.It is not clear how tachykinin antagonists exert their effect, but...
Investigational
R411
R411 is a non-steroid oral medicine for the treatment of asthma. It is not immunosuppressive, but blocks the activation and recruitment of cells involved in respiratory inflammation. It is a dual-acting competitive integrin antagonist (as compared to previously developed single integrin antagonists or SIAs) that prevents binding of V-CAM1 to...
Investigational
R450
R450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. It is being considered for treatment of stress-related urinary incontinence. Phase IIa data for the drug show it reduced the number of incontinent episodes compared to placebo with minimal cardiovascular effects.
Investigational
AICA ribonucleotide
5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. AICAR has been used clinically to treat and protect against cardiac ischemic injury. The drug was first used in the 1980s as...
Experimental
Investigational
Matched Synonyms: … 1-(5'-phosphoribosyl)-5-amino-4-imidazolecarboxamide ... 5-phosphoribosyl-4-carbamoyl-5-aminoimidazole ... 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Description: … 5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …
Matched Description: … 5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine …
Verpasep caltespen
Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational
ANA971
ANA971, an orally administered prodrug of isatoribine. Isatoribine is a nucleoside analog in development for the treatment of chronic hepatitis C virus (HCV) infection. ANA971 is a prodrug designed to improve the oral bioavailability of isatoribine. ANA971 resulted in higher levels of isatoribine in the blood than were present after...
Investigational
K-777
Investigational
Matched Iupac: … (2S)-N-[(1E,3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-yl]-2-{[(E)-4-methylpiperazine-1-carbonyl]amino …
D-arginine
A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active).
Experimental
Matched Synonyms: … (R)-2-amino-5-guanidinopentanoic acid ... D-2-Amino-5-guanidinovaleric acid ... (2R)-2-amino-5-guanidinopentanoic acid …
Matched Iupac: … (2R)-2-amino-5-carbamimidamidopentanoic acid …
Matched Iupac: … (2R)-2-amino-5-carbamimidamidopentanoic acid …
Displaying drugs 2651 - 2675 of 7096 in total