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Displaying drugs 2676 - 2700 of 9508 in total

Tibolone

Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha . Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Description: … and the treatment of post-menopausal symptoms [L1720]. ... In June 2006, Organon Pharmaceuticals announced the receipt of a Not Approvable Letter from the U.S. ... approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the development of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Gadoteric acid

Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Description: … [A263131] It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic ... [A263136] Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and ... its macrocyclic structure, and thus has a more favorable safety profile due to a decreased tendency of …
Matched Categories: … Diagnostic Uses of Chemicals …

Naloxone

Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Description: … within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. ... [L33724] Naloxone is indicated for the rapid reversal of these symptoms of central nervous system depression ... the opioid effect of buprenorphine. …
Matched Mixtures name: … TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADA ... TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADA …
Matched Products: … EVZIO(R) NALOXONE HCl …

Diphenoxylate

A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act...
Approved
Illicit
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Daratumumab

Daratumumab is an immunoglobulin G1 kappa monoclonal antibody developed by Janssen and Genmab. It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. Daratumumab was granted FDA approval on 16 November 2015. It is approved for...
Approved
Matched Description: … the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of ... [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and …
Matched Categories: … CD38 (Clusters of Differentiation 38) inhibitors …

Furosemide

Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... [A182495] The use of furosemide is particularly beneficial in clinical settings that require a drug with …
Matched Categories: … combinations of sulfonamides ... Increased Diuresis at Loop of Henle …

Warfarin

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally,...
Approved
Matched Description: … biologically active forms of various clotting factors in addition to several regulatory factors. ... Warfarin does not actually affect blood viscosity, rather, it inhibits vitamin-k dependent synthesis of …

Gadodiamide

Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Description: … agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of ... [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than …
Matched Categories: … Diagnostic Uses of Chemicals …

Gadopentetic acid

A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Approved
Matched Description: … A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic …
Matched Categories: … Diagnostic Uses of Chemicals …

Iodipamide

Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Gadofosveset trisodium

Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. The agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the...
Approved
Matched Description: … intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of ... In this way, gadofosveset trisodium is used to help diagnose certain disorders of the heart and blood …
Matched Categories: … Diagnostic Uses of Chemicals …

Bedaquiline

Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Description: … [L48506] Although the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key ... Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. ... fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Moxetumomab pasudotox

CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma. The predecessor of Moxetumab pasudotox (MxP), named BL22, was first created based on the antibody RFB4 which specifically binds to CD22. This antibody was used to...
Approved
Investigational
Matched Description: … [A38864] MxP appears as an improved form of BL22 by the mutation of the Fv region and the antibody ... The predecessor of Moxetumab pasudotox (MxP), named BL22, was first created based on the antibody RFB4 ... was developed by Astra Zeneca and FDA approved on September 13, 2018, after being granted the status of …
Matched Categories: … CD22 (Clusters of Differentiation 22) inhibitors …

Gelatin

Gelatin is a multifunctional ingredient that is used in foods, pharmaceuticals, cosmetics, and photographic films as a gelling agent, stabilizer, thickener, emulsifier, as well as film former. As a thermoreversible hydrocolloid with a small gap between its melting and gelling temperatures, gelatin provides unique advantages over carbohydrate-based gelling agents. Gelatin...
Approved
Vet approved
Withdrawn
Matched Description: … [L2121] Fish skins from a number of fish species a type of substance that has been comprehensively ... Gelatin continues to be approved for other routes of administration.[L43942] ... An increasing number of novel applications have been found for collagen and gelatin. …

Methazolamide

A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Approved
Matched Description: … A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma. …
Matched Categories: … combinations of sulfonamides …

Nialamide

Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Bazedoxifene

Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the...
Approved
Investigational
Matched Description: … their takeover of Wyeth Pharmaceuticals. ... prevention (not treatment) of postmenopausal osteoporosis. ... generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Iopamidol

Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Fusarium graminearum

Fusarium graminearum allergenic extract is used in allergenic testing.
Approved
Experimental

Aminosalicylic acid

An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Description: … The sodium salt of the drug is better tolerated than the free acid. …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Ampicillin

Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Description: … Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum …
Matched Categories: … combinations of penicillins …

Levorphanol

A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Iodixanol

Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Mangafodipir

Mangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. This drug is made up of paramagnetic manganese (II) ions combined with the chelating agent fodipir (dipyridoxyl diphosphate, DPDP). Manganese absorption into the tissues that...
Approved
Investigational
Withdrawn
Matched Description: … Enhanced contrast by mangafodipir improves visualization and detection of lesions of the liver formed ... diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of ... This drug is made up of paramagnetic manganese (II) ions combined with the chelating agent _fodipir_ …
Matched Categories: … Diagnostic Uses of Chemicals …

Ioversol

Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. Iodine has a high atomic density, which gives it the ability to attenuate X-rays. The intravascular administration of iodine compounds, such as ioversol, enhances...
Approved
Matched Description: … of internal structures. ... between vessels in the path of the flow of the contrast medium and normal tissue, allowing the visualization ... tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of …
Matched Categories: … Diagnostic Uses of Chemicals …
Displaying drugs 2676 - 2700 of 9508 in total