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Displaying drugs 2801 - 2825 of 7333 in total

D-arginine

A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active).
Experimental
Matched Synonyms: … (R)-2-amino-5-guanidinopentanoic acid ... D-2-Amino-5-guanidinovaleric acid ... (2R)-2-amino-5-guanidinopentanoic acid …
Matched Iupac: … (2R)-2-amino-5-carbamimidamidopentanoic acid …

(2R,4S)-2-[(1R)-1-{[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid

Experimental

6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one

Experimental
Matched Name: … 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one …

AAV9/MFSD8

AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Description: … It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. …

Ribose

Ribose is under investigation in clinical trial NCT01727479 (Ribose and Sport Performance).
Investigational

Denfivontinib

Investigational
Matched Synonyms: … 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one ... 8-bromo-2-[(1-methylpiperidin-4-yl)amino]-4-(4-phenoxyanilino)-6H-pyrido[4,3-d]pyrimidin-5-one …
Matched Iupac: … 8-bromo-2-[(1-methylpiperidin-4-yl)amino]-4-[(4-phenoxyphenyl)amino]-5H,6H-pyrido[4,3-d]pyrimidin-5-one …

Ocifisertib

Investigational
Matched Synonyms: … 1R,2S)-2-[3-[(1E)-2-[4-[[(2R,6S)-2,6-Dimethyl-4-morpholinyl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5′ ... 1R,2S)-2-{3-[(E)-2-(4-{[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl}phenyl)ethen-1-yl]-1Hindazol-6-yl}-5' ... )-one, 2-(3-((1e)-2-(4-(((2r,6s)-2,6-dimethyl-4-morpholinyl)methyl)phenyl)ethenyl)-1h-indazol-6-yl)-5' …

Dimefline

Experimental
Matched Iupac: … 8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenyl-4H-chromen-4-one …

PLX-R18

Investigational

Arbaclofen Placarbil

Arbaclofen Placerbil is a prodrug of Arbaclofen, which is a selective gamma-amino-butyric acid type B receptor agonist and the R-enantiomer of baclofen. It was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties....
Investigational
Matched Description: … prodrug of Arbaclofen, which is a selective gamma-amino-butyric acid type B receptor agonist and the R-enantiomer …

Fimaporfin

Investigational

(R)-warfarin

Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.
Experimental
Matched Synonyms: … R,R-Warfarin alcohol ... R-warfarin ... (R)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone …
Matched Name: … (R)-warfarin …
Matched Description: … S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A1038] ... Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared …

1-(5-phospho-D-ribosyl)-ATP

Experimental
Matched Name: … 1-(5-phospho-D-ribosyl)-ATP …
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-{1-[(3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-6-imino-6,9-dihydro …

5-fluorouridine

5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compounds comprising a pyrimidine base attached to a sugar. 5-fluorouridine is known to target uridine phosphorylase. FUrd is often used in chemical and biochemical...
Experimental
Matched Synonyms: … 5-Fur ... 5-Fluoro-uridine ... 5-Fluorouracil 1beta-D-ribofuranoside …
Matched Name: … 5-fluorouridine …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4 …
Matched Description: … 5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine ... . 5-fluorouridine is a solid. ... These are compounds comprising a pyrimidine base attached to a sugar. 5-fluorouridine is known to target …

Icaritin

Icaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
Investigational

5,7,2′-trihydroxy-6,8-dimethoxyflavone

5,7,2′-trihydroxy-6,8-dimethoxyflavone (K36) is a high-affinity, naturally occurring flavonoid derivative isolated from the medicinal herb Scutellaria baicalensis Georgi .
Experimental

Orforglipron

Orforglipron is under investigation in clinical trial NCT06010004 (A Long-term Safety Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes).
Investigational
Matched Synonyms: … -5-yl]carbonyl]-5-[(4S)-tetrahydro-2,2-dim ... -dihydro-1H-imidazol-1-yl]-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}carbonyl)-5-[(4S ... 1,2,4-Oxadiazol-5(2H)-one, 3-[(1S,2S)-1-[2-[[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl …

Cardiopet

Cardiopet is under investigation in clinical trial NCT01826773 (Cardiopet as PET Imaging Agent to Assess Myocardial Perfusion and Fatty Acid Uptake in Known or Suspected CAD Subjects).
Investigational
Matched Synonyms: … 2-((1s,2r)-2-(5-(fluoro-18f)tridecyl)cyclopropyl)acetic acid ... Cyclopropaneacetic acid, 2-(5-(fluoro-18f)tridecyl)-, (1r,2s)-rel- …

R1626

R1626 is one of a new class of hepatitis C therapies called polymerase inhibitors. It achieves significant reductions in viral load in chronic hepatitis C patients infected with the difficult to treat genotype 1 virus. R1626 is very effective in inhibiting viral replication
Investigational

R1295

R1295 is an integrin antagonist currently in clinical trials for the treatment of rheumatoid arthritis. Integrins are associated to the pathology seen in some of the autoimmune diseases such as rheumatoid arthritis.
Investigational

OCTANE-1,3,5,7-TETRACARBOXYLIC ACID

Experimental
Matched Iupac: … (1S,3R,5R)-1-methylheptane-1,3,5,7-tetracarboxylic acid …

CC-90001

Investigational
Matched Synonyms: … 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE ... 2-((1,1-DIMETHYLETHYL)AMINO)-4-(((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYL)AMINO)-5-PYRIMIDINECARBOXAMIDE ... 5-PYRIMIDINECARBOXAMIDE, 2-((1,1-DIMETHYLETHYL)AMINO)-4-(((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYL)AMINO …
Matched Iupac: … 2-(tert-butylamino)-4-{[(1R,3R,4R)-3-hydroxy-4-methylcyclohexyl]amino}pyrimidine-5-carboxamide …

VGM-R02b

Investigational

NCX 701

Nitroparacetamol (NCX-701) is a newly synthesized nitric oxide-releasing derivative of paracetamol.
Investigational

NOX-700

NOX-700, an new orally active dithiocarbamate-based nitric oxide (NO) blocking agent that is in development for the treatment of diabetes mellitus (type 2 diabetes). In animal studies, NOX-700 lowered serum glucose, improved glucose tolerance, and reduced the percentage of total glycated hemoglobin. Immunohistochemical studies on pancreatic tissue also showed that...
Investigational
Displaying drugs 2801 - 2825 of 7333 in total