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Did you mean bitopertin of ro 493838 of r 168 of ビトペルチン?
Displaying drugs 2826 - 2850 of 9627 in total

Rye

Rye allergenic extract is used in allergenic testing.
Approved

Meloxicam

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and...
Approved
Vet approved
Matched Description: … effects, however, this is a topic of controversy. ... Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including ... It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract …
Matched Products: … SINDULFAN (R) TABLETAS …

Dexketoprofen

Dexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America. It has analgesic, antipyretic and anti-inflammatory properties .
Approved
Investigational

Tegaserod

Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Description: … have resulted in the limited reintroduction or 're-approval' of tegaserod for treatment of IBS-C specifically ... in female patients less than 65 years of age and whom are considered to be at a lower risk of a cardiovascular ... name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Lofexidine

Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment...
Approved
Investigational
Matched Description: … non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of ... [T210] Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more ... antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Bupropion

Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
Matched Description: … [A178825,A1966,A16508] A Cochrane Review of meta-analyses of available treatment modalities for smoking ... rate of hypothalamic pro-opiomelanocortin (POMC) neurons and blockade of opioid receptor-mediated POMC ... the brain involved in the regulation of food intake. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Vortioxetine

Vortioxetine is an antidepressant medication indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake...
Approved
Investigational
Matched Description: … of these receptors appear to be involved in the antidepressant effects of SRIs. ... the serotonin transporter, as a partial agonist of the 5-HT1B receptor, an agonist of 5-HT1A, and an ... antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Lisinopril

Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Description: … [A184853] It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin ... [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension …
Matched Products: … ลิสพริล (R) 20 มก. …

Phenobarbital

A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Categories: … combinations of barbiturates ... Metabolic Side Effects of Drugs and Substances …

Rifamycin

Rifamycin is the prime member of the rifamycin family which are represented by drugs that are a product of fermentation from the gram-positive bacterium Amycolatopsis mediterranei, also known as Streptomyces mediterranei. The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence...
Approved
Investigational
Matched Description: … presence of diethylbarburitic acid. ... SV there was the first antibiotic used intravenously for the treatment of tuberculosis. ... Rifamycin is the prime member of the rifamycin family which are represented by drugs that are a product …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Quetiapine

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high...
Approved
Matched Description: … [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … QUETIAMET(R) 25 MG TABLETA RECUBIERTA …

Tenofovir alafenamide

Tenofovir alafenamide is a novel tenofovir prodrug developed in order to improve renal safety when compared to the counterpart tenofovir disoproxil. Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal...
Approved
Matched Description: … [A178060] Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Eletriptan

Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Approved
Investigational
Matched Description: … Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Sirolimus

Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria Streptomyces hygroscopicus, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island). It was first isolated and identified as an antifungal agent with potent anticandida activity; however, after its potent antitumor...
Approved
Investigational
Matched Description: … [A13448] Its primary mechanism of action is the inhibition of the mammalian target of rapamycin (mTOR ... the Vai Atari region of Rapa Nui (Easter Island). ... lactone antibiotic produced by bacteria _Streptomyces hygroscopicus_, which was isolated from the soil of …
Matched Categories: … Mammalian target of rapamycin (mTOR) kinase inhibitors …

Echinacea purpurea

Approved
Experimental

Thioridazine

A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Description: … Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal ... control of severely disturbed or agitated behavior. ... A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Glecaprevir

Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor that targets the the viral RNA replication. In combination with DB13878, glecaprevir is a useful therapy for patients who experienced therapeutic failure from other NS3/4A protease inhibitors. It demonstrates a high genetic barrier against resistance...
Approved
Investigational
Matched Description: … treatment, of ≥93% across genotypes 1a, 2a, 3a, 4, 5 and 6 [FDA Label]. ... It demonstrates a high genetic barrier against resistance mutations of the virus. ... The combinations of amino acid substitutions at NS3 position Y65H and D/Q168 also results in greater …
Matched Categories: … Antivirals for treatment of HCV infections …

Paliperidone

Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Description: … the other effects of the drug. ... Paliperidone is the primary active metabolite of risperidone. ... The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Cisapride

In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. The FDA issued a warning letter regarding this risk to health care professionals and patients.
Approved
Investigational
Withdrawn
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Phenelzine

Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Approved
Matched Description: … It is currently approved under prescription by the name of Nardil. ... β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Dihydroergotamine

A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile. Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Description: … 3-fold in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength of the existing ... A 9,10alpha-dihydro derivative of [ergotamine]. ... delivery of dihydroergotamine solution to the vasculature-rich upper nasal cavity. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Trimethoprim

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of ... tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately ... complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of …
Matched Mixtures name: … SOLASTEM(R) TABLETAS ... MEDIPRIM F (R) TABLETA ... MEDIPRIM F (R) TABLETA …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Rifabutin

A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Approved
Investigational
Matched Categories: … Drugs for Treatment of Tuberculosis …

Primidone

Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. Primidone was developed by J Yule Bogue and H C Carrington in 1949. Primidone was granted FDA Approval on 8 March 1954.
Approved
Vet approved
Matched Categories: … combinations of barbiturates …

Rubidium

Approved
Investigational
Displaying drugs 2826 - 2850 of 9627 in total