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Displaying drugs 2876 - 2900 of 3539 in total
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and
Matched Products: … ESCITALOPRAM DOC ... ESCITALOPRAM DOC GENERICS ... ESCITALOPRAM DOC GENERICI …
Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Approved
Investigational
Matched Description: … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol …
Matched Mixtures name: … Prenatal Vitamin and Mineral Supplement ... Multiple Vitamins and Minerals ... Calcium and Magnesium W Zinc Tab …
Matched Categories: … Sulfur Acids ... Sulfuric Acids ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … ZINK BETA 25 ... SULFATO DE ZINC 2MG/ML SOLUCION ORAL SABOR A CEREZA Y SABOR A CHICLE. …
Ebvaciclib is under investigation in clinical trial NCT03519178 (A Study of PF-06873600 in People With Cancer).
Investigational
Matched Synonyms: … )-8-((1r,2r)-2-hydroxy-2-methylcyclopentyl)-2-((1- (methylsulfonyl)piperidin-4-yl) amino)pyrido(2,3-d) ... Pyrido(2,3-d)pyrimidin-7(8h)-one, 6-(difluoromethyl)-8-((1r,2r)-2-hydroxy-2-methylcyclopentyl)-2-((1- …
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Synonyms: … Pyridoxal 5-monophosphoric acid ester …
Matched Iupac: … [(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid
Matched Description: … During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine ... phosphate (pyridoxamine). ... (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil ... BumP DHA ... BumP DHA
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Experimental
Matched Synonyms: … Carbonic acid, 2-hydroxypropyl (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester …
Investigational
Matched Synonyms: … (s)-2-acetamido-4-methylpentanoic acid
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LETROZOL BETA 2.5MG FTA ... Dom-letrozole ... LETROZOLO DOC GENERICI …
Experimental
Matched Name: … 3S,5S)-2-(Hydroxymethyl)-5-[(2-sulfoethyl)carbamoyl]-3-pyrrolidiniumyl 2-acetamido-2-deoxy-4-O-sulfo-beta-D-glucopyranoside …
Fimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.
Investigational
Matched Synonyms: … 5-pyrimidinecarboxamide, N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin ... N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and
Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and survival. FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed...
Approved
Investigational
Matched Synonyms: … 1-((3S)-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo(3, 4-d) pyrimidin-1-yl)-1-pyrrolidinyl) ... 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl] …
Matched Iupac: … 1-[(3S)-3-{4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl …
Matched Description: … of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and ... FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated ... FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Approved
Vet approved
Withdrawn
Matched Synonyms: … carbamic acid 3-(p-chlorophenoxy)-2-hydroxypropyl ester …
Barzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).
Investigational
Matched Synonyms: … Immunoglobulin G1 [233-alanine,234-glutamine,251-tyrosine,253-threonine,255-glutamic acid,321-glutamine ... ,de-C-terminal-lysine], anti-(human receptor tyrosine kinase KIT extracellular domain) (human-Mus musculus …
Dazodalibep is under investigation in clinical trial NCT06104124 (A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity).
Investigational
Matched Synonyms: … CD40 LIGAND-BINDING THIRD FIBRONECTIN TYPE III DOMAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 19-AMINO ACID
Matched Description: … Dazodalibep is under investigation in clinical trial NCT06104124 (A Study to Evaluate the Efficacy and
Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Synonyms: … 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha …
Matched Description: … that early antiviral treatment can shorten the duration of fever and illness symptoms, and may reduce ... effects and renal adverse events in adults and vomiting in children, the harms are generally considered ... (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and
Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Synonyms: … acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor ... Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor …
Matched Products: … Dom-famciclovir …
Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasting effects, doxazosin can be administered once a day. It is marketed by Pfizer and was initially approved...
Approved
Matched Description: … Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and ... Other members of this drug class include [Prazosin], [Terazosin], [Tamsulosin], and [Alfuzosin]. ... [A180649] It is marketed by Pfizer and was initially approved by the FDA in 1990.[L7285] …
Matched Mixtures name: … Cardura-1,2,and 4 ... Cardura-1,2,and 4 ... Cardura-1,2,and 4 …
Matched Categories: … doxazosin and finasteride ... Genito Urinary System and Sex Hormones …
Matched Products: … DOXAZOSIN ACINO 4MG ... Dom-doxazosin ... DOXAZOSIN DOC GENERICI …
Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not...
Approved
Matched Synonyms: … 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one …
Matched Description: … It is a derivative of 19-nortestosterone and has antiandrogenic properties. ... Dienogest is commonly marketed as Visanne, Natazia and Qlaira. ... in combination with ethinylestradiol, or in other combination form pills approved in United States and
Matched Mixtures name: … Estradiol Valerate and Estradiol Valerate/Dienogest ... Estradiol Valerate and Estradiol Valerate/Dienogest …
Matched Categories: … dienogest and estrogen ... dienogest and estradiol ... Combination Contraceptives (with Estrogen and derivatives) ... Genito Urinary System and Sex Hormones ... dienogest and ethinylestradiol …
Matched Products: … DIENOGEST E ETINILESTRADIOLO DOC
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... [A182579] Nebivolol and other beta blockers are generally not first line therapies as many patients are ... first treated with thiazide diuretics. …
Matched Mixtures name: … NEBIVOLOLO E IDROCLOROTIAZIDE DOC GENERICI ... NEBIVOLOLO E IDROCLOROTIAZIDE DOC GENERICI …
Matched Salts name: … Nebivolol hydrochloride
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides ... Beta blocking agents and calcium channel blockers ... valsartan and nebivolol ... nebivolol and thiazides …
Matched Products: … NEBIVOLOLO DOC ... NEBIVOLOL HYDROCHLORIDE ... NEBIVOLOLO DOC GENERICI …
Experimental
Matched Name: … C-(1-Azido-Alpha-D-Glucopyranosyl) Formamide …
Experimental
Matched Name: … D-leucyl-N-(3-chlorobenzyl)-L-prolinamide …
Experimental
Matched Name: … D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamide …
Experimental
Matched Name: … D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide …
Doxifluridine has been investigated for the treatment of Stomach Cancer.
Investigational
Matched Synonyms: … 1-(β-D-5-desoxyribofuranoxyl)-5-fluoruracil …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Fluorouracil and prodrugs …
Hyperpolarized Xenon-129 (Xe-129) is a contrast agent used in the lung's clinical magnetic resonance imaging (MRI). Lung MRIs are challenging due to the low proton density of this tissue, as well as the presence of artifacts due to respiration and cardiovascular pulsation movement and air–tissue interfaces.[A255178,A255183] The use of hyperpolarized...
Approved
Matched Synonyms: … Xenon, isotope of mass 129m(8.88 d) …
Matched Description: … due to respiration and cardiovascular pulsation movement and air–tissue interfaces. ... [Helium-3] (He-3) is the one most commonly used due to its strong signal and favorable safety profile ... [A255178] Xe-129 has a lower cost, and adverse effects are normally resolved shortly after administration …
Experimental
Matched Synonyms: … 4-[[(1S)-1-(4,8-dichloro-1-oxo-2-phenylisoquinolin-3-yl)ethyl]amino]-8H-pyrido[2,3-d]pyrimidin-5-one …
Displaying drugs 2876 - 2900 of 3539 in total