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Displaying drugs 2926 - 2950 of 3766 in total
Ceforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to...
Approved
Matched Synonyms: … (carboxymethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... aminomethyl)phenylacetamido]-3-[[[1-(carboxymethyl)-1H-tetrazol-5-yl]thio]methyl]-3-cephem-4-carboxylic acid ... phenyl]acetamido-3-{[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl-3,4-didehydrocepham-4-carboxylic acid
Matched Iupac: … carboxymethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species ... Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ... It has a longer elimination half-life than any currently available cephalosporin. …
Matched Categories: … Sulfur Compounds …
Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other GnRH receptor antagonists like cetrorelix, relugolix, and elagolix. Uterine fibroids occur in >70% of women of reproductive...
Approved
Matched Synonyms: … methoxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno(3,4-d)pyrimidine-5-carboxylic acid ... Thieno(3,4-d)pyrimidine-5-carboxylic acid, 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl …
Matched Iupac: … methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl}-2,4-dioxo-1H,2H,3H,4H-thieno[3,4-d]pyrimidine-5-carboxylic acid
Matched Description: … Uterine fibroids occur in >70% of women of reproductive age, and when symptomatic are associated with ... , and reproductive dysfunction. ... It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins …
Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Synonyms: … hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid ... methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid
Matched Iupac: … )-2-propyl-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid
Matched Description: … cardiac activity, and increased excretion of sodium. ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... in hemostasis and regulation of kidney, vascular, and cardiac functions. …
Matched Mixtures name: … Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil …
Matched Categories: … olmesartan medoxomil and diuretics ... olmesartan medoxomil and amlodipine ... Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... olmesartan medoxomil, amlodipine and hydrochlorothiazide …
Matched Products: … Ag-olmesartan ... Apo-olmesartan ... Ach-olmesartan …
Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Experimental
Matched Synonyms: … (2S)-Amino(4-Hydroxyphenyl)Acetic Acid
Matched Iupac: … (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid
Matched Description: … Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Experimental
Matched Synonyms: … (S)-2-Amino-3-(naphthalen-1-yl)propanoic acid
Matched Iupac: … (2S)-2-amino-3-(naphthalen-1-yl)propanoic acid
Experimental
Matched Synonyms: … 2β,4a-dihydroxy-1-methyl-8-methylene-4aα,4bβ-gibbane-1α,10β-dicarboxylic acid, 1,4a-lactone …
Matched Name: … Gibberellin A4
Matched Iupac: … methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.1^{5,8}.0^{1,10}.0^{2,8}]heptadecane-9-carboxylic acid
Investigational
Matched Synonyms: … Hexadecanoic acid, 5,6,6a,7-tetrahydro-6-methyl-4h-dibenzo(de,g)quinoline-10,11-diyl ester, (r)- …
Investigational
Matched Synonyms: … Butanoic acid, 4-[[2-(acetylamino)ethyl]thio]-4-oxo-, methyl ester …
Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing tablets. These tablets allow patients to visualise areas where more brushing and...
Approved
Matched Synonyms: … CI Acid Red 92 …
Matched Description: … These tablets allow patients to visualise areas where more brushing and flossing are needed. ... is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing ... Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Investigational
Matched Synonyms: … Hexanoic acid, 3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethyl)phenyl)-1h-imidazol-1-yl)methyl)phenoxy …
Matched Iupac: … 3R)-3-methyl-6-[2-({5-methyl-2-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl}methyl)phenoxy]hexanoic acid
Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.
Approved
Matched Description: … ovarian cancer), lymphomas and germ cell tumors. ... It was the first member of its class, which now also includes carboplatin and oxaliplatin. ... to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Indicators and Reagents ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Drugs that are Mainly Renally Excreted ... OCT2 Substrates with a Narrow Therapeutic Index …
Matched Products: … Platinol-AQ ... Platinol AQ Inj 1mg/ml ... CISPLATINO 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Experimental
Matched Name: … }-BUTYRIC ACID ... 4-{4-[2-(1A,7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL …
Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Synonyms: … N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester ... N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester …
Matched Description: … ) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures ... It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED ... Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. …
Matched Categories: … Drugs that are Mainly Renally Excreted ... Acids, Acyclic ... Carboxylic Acids
Investigational
Matched Synonyms: … 3-((2,6-dichloro-7-fluoro-1-(1-propyl-1h-pyrazol-4-yl)-1h-indol-3-yl)thio)-2-fluorobenzoic acid ... Benzoic acid, 3-((2,6-dichloro-7-fluoro-1-(1-propyl-1h-pyrazol-4-yl)-1h-indol-3-yl)thio)-2-fluoro- …
Matched Iupac: … 3-{[2,6-dichloro-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl]sulfanyl}-2-fluorobenzoic acid
Matched Salts name: … Cudetaxestat sodium
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid ... -fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
Matched Iupac: … fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Matched Description: … A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid and is the ... in lipid metabolism and transport including cholesterol, low-density lipoprotein (LDL) (sometimes referred ... to as "bad cholesterol"), and very low-density lipoprotein (VLDL). …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … rosuvastatin and acetylsalicylic acid ... Sulfur Compounds ... Alimentary Tract and Metabolism ... rosuvastatin and valsartan ... rosuvastatin and ramipril …
Matched Products: … Ag-rosuvastatin ... Apo-rosuvastatin ... Ach-rosuvastatin …
Glycol salicylate, also known as 2-hydroxyethyl salicylate, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol. It is found as an active ingredient and topical analgesic in patches used to provide relief for mild to...
Approved
Matched Synonyms: … 2-hydroxybenzoic acid 2-hydroxyethyl ester …
Matched Description: … Glycol salicylate (GS), composed of salicylic acid (SA) and ethylene glycol, is a non-steroidal anti-inflammatory ... pains, and stiffness of the muscles, joints, and tendons [L2696]. ... It is found as an active ingredient and topical analgesic in patches used to provide relief for mild …
Matched Mixtures name: … Salonpas - Pls Top
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Investigational
Matched Synonyms: … )-(polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid
Investigational
Matched Synonyms: … Undecanoic acid, 2-((4,5-dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)methylene)-, (2e)- …
Matched Name: … APX-3330 …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … Cl-F-Ara-A
Matched Description: … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. ... Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been ... leukaemia (ALL), only after at least two other types of treatment have failed. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors ... Drugs that are Mainly Renally Excreted ... OCT2 Substrates with a Narrow Therapeutic Index …
Experimental
Matched Name: … 4-{[5-(CYCLOHEXYLMETHOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE …
Matched Iupac: … 4-{[5-(cyclohexylmethoxy)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzene-1-sulfonamide …
Experimental
Matched Name: … 5-chloro-7-[(1-methylethyl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile …
Matched Iupac: … 5-chloro-7-[(propan-2-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile …
Experimental
Matched Name: … 2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE …
Matched Iupac: … 2-[(cyclohexylmethyl)amino]-4-(phenylamino)pyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile …
Experimental
Matched Synonyms: … alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GlcpNAc …
Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label]. The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar collapse leading to acute respiratory collapse.
Approved
Experimental
Matched Synonyms: … l-Alpha-1-palmitoyl-2-oleoylglycerophosphoglycerol …
Matched Iupac: … (2,3-dihydroxypropoxy)[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acid
Matched Description: … The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar ... a surfactant [FDA Label]. ... Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as
Matched Salts name: … 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt …
Experimental
Matched Name: … N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]Acetamide …
Matched Iupac: … N-(4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)acetamide …
Displaying drugs 2926 - 2950 of 3766 in total