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Displaying drugs 276 - 300 of 358 in total
Oxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was first approved for use in the United States in 2000.[L8627,L8630,L8633] It is a structural derivative of carbamazepine and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate...
Approved
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and...
Approved
Hydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by dextromethorphan in current cough and cold formulations. Hydrocodone's more potent metabolite, hydromorphone...
Approved
Illicit
Investigational
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Salts name: … Glucosamine sulfate potassium chloride …
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Mixtures name: … Chela Potassium Plus ... Potassium Plus Vit B Complex …
Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.[A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. However, its clinical efficacy as...
Approved
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Salts name: … Potassium aminosalicylate …
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Severe acute pain occurs through nociceptive signalling involving both ascending and descending spinal pathways, in which nerve conductance is mediated in part by the action of opioid receptors.[A218041, A218046] Opioid receptors are seven-transmembrane G-protein-coupled receptors (GPCRs), of which the μ-opioid receptor subtype is predominantly targeted by and is responsible for...
Approved
Investigational
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Approved
Investigational
Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where...
Approved
Investigational
Experimental
Matched Synonyms: … Josamycin propionate
Matched Name: … Josamycin propionate
Experimental
Matched Synonyms: … L-Carnitine propionate
Matched Name: … Levocarnitine propionate
Matched Salts name: … Levocarnitine propionate hydrochloride …
Experimental
Matched Synonyms: … Potassium disulfite ... Potassium metabisulfite ... Potassium pyrosulfite …
Matched Name: … Potassium metabisulfite …
Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. It is obtained as a byproduct of wine manufacture during the fermentation process. Approved by the FDA as a direct food substance, potassium bitartrate is used as...
Experimental
Matched Synonyms: … Potassium bitartrate ... potassium hydrogen tartrate …
Matched Name: … Potassium bitartrate …
Matched Iupac: … potassium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate …
Matched Description: … Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium ... Approved by the FDA as a direct food substance, potassium bitartrate is used as an additive, stabilizer ... Potassium bitartrate was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that …
Matched Categories: … Potassium Salt …
Experimental
Investigational
Matched Synonyms: … Potassium permanganate …
Matched Name: … Potassium permanganate …
Matched Iupac: … potassium manganesoylolate …
Matched Categories: … Potassium Salt ... Potassium Compounds ... potassium permanganate ... potassium permanganate …
Experimental
Matched Synonyms: … Iodic acid, potassium salt …
Matched Name: … Potassium iodate …
Matched Iupac: … potassium iodate …
Experimental
Matched Synonyms: … Potassium glycerophosphate anhydrous …
Matched Name: … Potassium glycerophosphate …
Experimental
Matched Synonyms: … Potassium triiodide …
Matched Name: … Potassium triiodide …
Matched Iupac: … potassium triiodan-2-uide …
Matched Categories: … Potassium Salt …
Antimony potassium tartrate is a schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.
Experimental
Matched Synonyms: … Antimony potassium tartrate ... Potassium antimonyl tartrate ... Potassium antimonyl D-tartrate …
Matched Name: … Antimony potassium tartrate …
Matched Description: … Antimony potassium tartrate is a schistosomicide possibly useful against other parasites. …
Experimental
Matched Synonyms: … Potassium sodium hydrogen citrate ... Sodium potassium hydrogen citrate …
Matched Name: … Potassium sodium hydrogen citrate …
Displaying drugs 276 - 300 of 358 in total