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Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. It is an outdated drug, and its approval has been discontinued by the FDA. Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. The sodium salt of a mercury-containing derivative of salicylamide, was formerly...
Experimental
Matched Synonyms: … Acidum mersalylicum …
Matched Iupac: … 2-(2-{[3-(hydroxymercurio)-2-methoxypropyl]carbamoyl}phenoxy)acetic acid
Matched Description: … It is an outdated drug, and its approval has been discontinued by the FDA. ... Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. ... Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. …
Matched Salts name: … Mersalyl sodium
Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.
Approved
Experimental
Matched Synonyms: … (beta-phenoxyethyl)dimethyldodecylammonium …
Matched Mixtures name: … Mouthwash and Gargle ... Lander Orl Hygienic Mwh and Gargle …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Experimental
Matched Name: … METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE
Matched Iupac: … 2-[(1R)-1-(acetyloxy)-2-methoxy-2-oxoethyl]-5-aminobenzoic acid
Experimental
Matched Synonyms: … (2S)-2-[3-[(2-bromoacetyl)amino]propanoylamino]-3-hydroxypropanoyl]amino]ethyl]anilino]-2-oxoacetic acid
Matched Name: … N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide …
Matched Iupac: … [(4-{2-[(2S)-2-[3-(2-bromoacetamido)propanamido]-3-hydroxypropanamido]ethyl}phenyl)carbamoyl]formic acid
Investigational
Matched Synonyms: … 153sm-1,4,7,10-tetraazacyclododecane-1,4,7,10- tetramethylene-phosphonic acid
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... captopril and diuretics ... Amino Acids ... Imino Acids
Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … -1'-ethyl-spiro(cyclohexane-1,2'-pyrrolidine)-5'-carbonyl)-amino)-bicyclo(2.2.2)octane-1-carboxylic acid ... Bicyclo(2.2.2)octane-1-carboxylic acid, 4-((((3'r,4's,5'r)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1' ... oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo [2.2.2]octane-1-carboxylic acid
Matched Iupac: … dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … rIFN-alpha-2a ... Interferon alpha-2a …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... A type I interferon consisting of 165 amino acid residues with lysine in position 23. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Interferon alpha ... Interferon-alpha
Investigational
Matched Synonyms: … 9h-pyrido(3',4':4,5)pyrrolo(2,3-b)pyridine, 2-(2-fluoro-4-pyridinyl)- …
Investigational
Matched Synonyms: … ethoxy}-ethoxy)-ethyl]-1H-[1,2,3]triazol-4-ylmethoxy}-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-acetic acid ... ]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methoxy]-3,5-diiodophenoxy]-3,5-diiodophenyl]acetic acid
Matched Iupac: … 3,6,9,12,15,18-hexaoxaicosan-1-yl}-1H-1,2,3-triazol-4-yl)methoxy]-3,5-diiodophenoxy}-3,5-diiodophenyl)acetic acid
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has...
Approved
Investigational
Withdrawn
Matched Description: … Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and ... primary dysmenorrhoea in adolescents and adults above 12 years old. ... Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and
Matched Categories: … Calcium Channel Blockers ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … AULIN BETA
Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Synonyms: … 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene ... 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene …
Matched Description: … treatment for these types of cancers as patients generally have better survival, side effect profiles, and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Name: … N-acetyl-beta-D-galactosamine 6-sulfate …
Matched Iupac: … {[(2R,3R,4R,5R,6R)-5-acetamido-3,4,6-trihydroxyoxan-2-yl]methoxy}sulfonic acid
Experimental
Matched Name: … C-(1-hydrogyl-beta-D-glucopyranosyl) formamide …
Experimental
Matched Name: … 4-Deoxy-4-Amino-Beta-D-Glucose …
Experimental
Matched Name: … 1-deoxy-1-methoxycarbamido-beta-D-glucopyranose …
Matched Iupac: … methyl N-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]carbamate
Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agricultural and medical purposes. It is a perennial succulent xerophyte with elongated...
Experimental
Matched Synonyms: … Aloe folium (aloe vera) ... Aloe folii extractus (aloe vera) …
Matched Description: … genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and ... or _Aloe barbadensis miller_, is the most common species of Aloe that is cultivated for agricultural and ... While aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and
Matched Mixtures name: … Mousturizing Gloves and Socks ... Niacinamide Serum ... Iodoquinol Hydrocortisone Acetate Aloe Polysaccharides …
Experimental
Matched Name: … O-(N-acetyl-alpha-D-galactosaminyl)-L-serine …
Matched Iupac: … 2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propanoic acid
Experimental
Matched Name: … N-(R-Carboxy-Ethyl)-Alpha-(S)-(2-Phenylethyl) …
Matched Iupac: … -[(1H-imidazol-2-yl)methyl]piperidin-4-yl}-1-(4-pentylphenyl)formamido)methyl]-[1,1'-biphenyl]-4-yl}acetate
Experimental
Matched Name: … Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanine …
Matched Iupac: … (2S)-2-(2-aminoacetamido)-6-{[(1R)-1-carboxyethyl]carbamoyl}hexanoic acid
Experimental
Matched Synonyms: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid
Matched Iupac: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. Carbocisteine is a mucolytic drug...
Approved
Investigational
Matched Synonyms: … (L)-2-Amino-3-(carboxymethylthio)propionic acid
Matched Iupac: … (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid
Matched Description: … Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other ... viruses and bacteria in thick bronchial mucus. ... by physicians in France and Italy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
INCB-086550 is under investigation in clinical trial NCT04629339 (Study of INCB086550 in Select Solid Tumors).
Investigational
Matched Synonyms: … 3-PYRROLIDINECARBOXYLIC ACID, 1-((7-CYANO-2-(3'-((3-(((3R)-3-HYDROXY-1-PYRROLIDINYL)METHYL)-1,7-NAPHTHYRIDIN …
Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and apoptosis of cancer cells,...
Approved
Investigational
Matched Synonyms: … [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... and mantle cell lymphoma. ... ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids ... Boronic Acids ... Acids, Noncarboxylic …
MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Synonyms: … 3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine …
Matched Description: … It also acts as an entheogen and an entactogen. ... or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and ... MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Displaying drugs 3001 - 3025 of 3723 in total