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Displaying drugs 3126 - 3150 of 3868 in total
A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
Approved
Investigational
Matched Synonyms: … [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and ... It has a high rate of efficacy in many types of infection and to date no severe side effects have been …
Matched Categories: … Thiazines
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Approved
Investigational
Matched Synonyms: … [1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … sulfomethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone …
Matched Categories: … Thiazines
Matched Products: … CEFONICID DOC GENERICI …
Experimental
Matched Name: … acid ... (7R)-7-(6,7-Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic …
Matched Iupac: … diazatricyclo[6.3.0.0^{2,6}]undeca-2(6),8,10-trien-10-yl}-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid
AR-42 has been used in trials studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and Vestibular Schwannoma, among others.
Investigational
Matched Synonyms: … BENZENEACETAMIDE, N-(4-((HYDROXYAMINO)CARBONYL)PHENYL)-.ALPHA.-(1-METHYLETHYL)-, (.ALPHA.S)- …
Matched Description: … studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Immunoglobulin G1 (de-236-glycine,267-glutamic acid,de-C-terminal lysine), anti-(human tumor necrosis …
Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Synonyms: … carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Iupac: … carbonyl)amino]-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Mixtures name: … DBL PIPERACILLIN AND TAZOBACTAM FOR INJECTION 4.5 G ... Piperacillin and Tazobactam ... Piperacillin and Tazobactam …
Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasting effects, doxazosin can be administered once a day. It is marketed by Pfizer and was initially approved...
Approved
Matched Description: … and hypertension. ... Other members of this drug class include [Prazosin], [Terazosin], [Tamsulosin], and [Alfuzosin]. ... [A180649] It is marketed by Pfizer and was initially approved by the FDA in 1990.[L7285] …
Matched Mixtures name: … Cardura-1,2,and 4 ... Cardura-1,2,and 4 ... Cardura-1,2,and 4 …
Matched Categories: … doxazosin and finasteride ... Genito Urinary System and Sex Hormones ... Adrenergic alpha-Antagonists ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … DOXAZOSIN ACINO 4MG ... Dom-doxazosin ... DOXAZOSIN DOC GENERICI …
Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. The product label for carbinoxamine as an over the counter cough and...
Approved
Matched Synonyms: … 2-(p-chloro-α-(2-(dimethylamino)ethoxy)benzyl)pyridine
Matched Description: … to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many ... The product label for carbinoxamine as an over the counter cough and cold medicine is being modified ... labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and
Matched Mixtures name: … Coldec DS ... Rondamine DM ... Carbinoxamine/Pseudoephedrine/DM
Aloe ferox leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Aloe Ferox Dry Leaf Juice ... Aloe Folium (Aloe Ferox) ... Aloe Folii Extractus (Aloe Ferox) …
Investigational
Matched Synonyms: … 4-methylpiperazine-1-carboxylic acid [1-(3-benzenesufonyl-1-phenethylallyl-carbamoyl)-2-phenylethyl] ... 4-methylpiperazine-1-carboxylic acid(1-((3-benzenesufonyl-1-phenethylallyl)carbamoyl)-2-phenylethyl)amide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Amino Acids, Essential …
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Synonyms: … (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol …
Matched Description: … [Carvedilol] and [Labetalol]. ... and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such as ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … CORBIS® D ... Bisoprolol Fumarate and Hydrochlorothiazide ... Bisoprolol Fumarate and Hydrochlorothiazide …
Matched Categories: … bisoprolol and acetylsalicylic acid ... Beta Blocking Agents and Thiazides ... Beta blocking agents and calcium channel blockers ... ramipril and bisoprolol ... bisoprolol and thiazides …
Matched Products: … Dom-bisoprolol ... BISOPROLOLO DOC GENERICI ... BISOPROLOLO DOC GENERICS …
Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).
Investigational
Matched Synonyms: … MONOCLONAL ALXN1720 SINGLE-DOMAIN VHH FRAGMENT) FUSION PROTEIN WITH PEPTIDE LINKER (SYNTHETIC 15 AMINO-ACID
Matched Description: … Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in …
A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid
Matched Iupac: … 9-ethyl-4,6-dioxo-10-propyl-4H,6H,9H-chromeno[7,6-b]pyridine-2,8-dicarboxylic acid
Matched Description: … are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and
Matched Categories: … Decongestants and Antiallergics …
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … and stimulated gastric acid secretion. ... Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal ... It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form …
Matched Categories: … Acetates ... Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... rabeprazole, amoxicillin and metronidazole …
Matched Products: … Rabeprazole Sodium DR ... Raberprazole Sodium D/r ... Dom-rabeprazole EC …
Experimental
Matched Synonyms: … D-Propranolol …
Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug...
Approved
Investigational
Matched Synonyms: … Caproato de hidroxiprogesterona ... 17-alpha-hydroxy-progesterone caproate …
Matched Description: … and megestrol acetate. ... It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). ... Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.[L46118] The U.S. …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Progesterone and Derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PROLUTON DEPOT AMPOLLAS DE 500 MG …
Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Withdrawn
Matched Synonyms: … bis(4-methylbenzoic acid) 4-[2-(tert-butylamino)-1-hydroxyethyl]-1,2-phenylene ester ... 4-(2-(tert-butylamino)-1-hydroxyethyl)-o-phenylene di-p-toluate ... 4-[2-(tert-butylamino)-1-hydroxyethyl]-o-phenylene di-p-toluate …
Matched Description: … Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. …
Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family. In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further...
Approved
Investigational
Matched Synonyms: … 2-propen-1-one, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-D)pyrimidin-4-ylamino)-1-piperidinyl)- …
Matched Iupac: … 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one …
Matched Description: … 12 years and older. ... Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine ... [L48181] Ritlecitinib is administered orally and is the first member of its class. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab in Rhd-negative Pregnant Women Carrying an Rhd-positive Foetus).
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(homo sapiens rhd(rhesus blood group d antigen, rhd, cd240d)), homo sapiens …
Matched Description: … Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab …
Pamapimod is under investigation in clinical trial NCT05659459 (The KIN-FAST Trial (KIN001 for Accelerated Symptoms Termination) in Non Hospitalized Patients Infected With Sars-cov-2).
Investigational
Matched Synonyms: … 6-(2,4-Difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxyethyl)propyl]amino}-8-methylpyrido[2,3-d]pyrimidin- …
Investigational
Matched Synonyms: … fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human lysosomal .alpha ... Immunoglobulin g1, (humanized monoclonal 3e10 .gamma.1-chain fab fragment) fusion protein with 67-952-lysosomal .alpha
One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Approved
Investigational
Matched Synonyms: … dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … ethyl]-1H-1,2,3,4-tetrazol-5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative …
Matched Salts name: … Cefotiam hydrochloride
Matched Categories: … Thiazines
Experimental
Matched Synonyms: … bromo-N-hydroxyanilino)-hydroxymethyl]sulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Matched Iupac: … bromophenyl)(hydroxy)amino](hydroxy)methyl]sulfanyl}-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Synonyms: … [3(S)-endo]-α-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester …
Matched Description: … [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic ... Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... hyoscyamine and psycholeptics …
Matched Products: … HyoMax-DT
Displaying drugs 3126 - 3150 of 3868 in total