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Displaying drugs 3151 - 3175 of 3224 in total
Suramin
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Suramin...
Investigational
Matched Categories: … Anti-Infective Agents …
Methapyrilene
Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Withdrawn
Matched Categories: … Anti-Allergic Agents …
Bergapten
Bergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).
Investigational
Matched Categories: … Anti-Inflammatory Agents …
Etrolizumab
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is typified by a chronic gastrointestinal inflammatory microenvironment, driven in part by the excessive infiltration and retention of intestinal-homing lymphocytes.[A244564, A244569, A244579, A244584] A recent class of drugs designed to impair lymphocyte homing, so-called "anti-trafficking agents" (ATAs), have shown some...
Investigational
Matched Description: … A244569, A244579, A244584] A recent class of drugs designed to impair lymphocyte homing, so-called "anti-trafficking …
Roxatidine acetate
Roxatidine acetate is a specific and competitive H2 receptor antagonist. It is currently approved in South Africa under the tradename Roxit.
Experimental
Matched Categories: … Anti-Ulcer Agents …
Tandospirone
Tandospirone has been used in trials studying the treatment of Schizophrenia.
Investigational
Matched Categories: … Anti-Anxiety Agents …
Fludiazepam
Fludiazepam is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a scheduled drug in the U.S., but is approved for use in Japan.
Experimental
Illicit
Matched Categories: … Anti-Anxiety Agents …
Lisofylline
Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
Investigational
Matched Categories: … Anti-Inflammatory Agents …
Lonidamine
Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs.
Investigational
Matched Categories: … Anti-Infective Agents …
Homidium
Homidium is a group II compound with trypanocidal effects.
Investigational
Matched Categories: … Anti-Infective Agents …
Bitolterol
Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Withdrawn
Matched Categories: … Anti-Asthmatic Agents …
Nordazepam
An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.
Experimental
Matched Categories: … Anti-Anxiety Agents …
Molnupiravir
Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of N4-hydroxycytidine.[A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed in vivo, and distributes into tissues where it becomes the active 5’-triphosphate form. The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as...
Investigational
Matched Categories: … Anti-Infective Agents …
Lafutidine
Lafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD).
Investigational
Matched Categories: … Anti-Ulcer Agents …
Seratrodast
Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Experimental
Matched Categories: … Anti-Asthmatic Agents ... Anti-Inflammatory Agents …
Quinacrine
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Investigational
Matched Categories: … Anti-Infective Agents …
Displaying drugs 3151 - 3175 of 3224 in total