Displaying drugs 3176 - 3200 of 3868 in total
Mizagliflozin
Mizagliflozin is under investigation in clinical trial NCT05721729 (Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions).
Investigational
Matched Synonyms: … -d-glucopyranosyloxy)-5-(1-methylethyl)-1h-pyrazol-4-yl)methyl)-3-methylphenoxy)propyl)amino)-2,2-dimethyl ... -d-glucopyranosyloxy)-5-(propan-2-yl)-1h-pyrazol-4-yl)methyl)-3-methylphenoxy)propyl)amino)-2,2-dimethylpropanamide …
Matched Description: … investigation in clinical trial NCT05721729 (Effect of Mizagliflozin Repeat Dosing on Adverse Events and …
Matched Description: … investigation in clinical trial NCT05721729 (Effect of Mizagliflozin Repeat Dosing on Adverse Events and …
2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID
Experimental
Matched Name: … ACID ... 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC …
Matched Iupac: … acid ... (2S)-2-{[4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-3-methylbutanoic …
Matched Iupac: … acid ... (2S)-2-{[4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-3-methylbutanoic …
(5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE
Experimental
Matched Name: … 6-OXIDE ... 8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID …
Matched Iupac: … aminomethyl)phenyl]-2-({[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-methylpropyl](hydroxy)phosphoryl}oxy)acetic acid …
Matched Iupac: … aminomethyl)phenyl]-2-({[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-methylpropyl](hydroxy)phosphoryl}oxy)acetic acid …
Cemdomespib
Cemdomespib is under investigation in clinical trial NCT05895552 (A Phase 2 Study of RTA 901 in Patients With Diabetic Peripheral Neuropathic Pain (CYPRESS)).
Investigational
Matched Synonyms: … Acetamide, n-(2-(5-((6-deoxy-5-c-methyl-4-o-methyl-.alpha. …
1D-myo-inositol 1,3,4-trisphosphate
Experimental
Matched Synonyms: … D-myo-Inositol 1,3,4-trisphosphate …
Matched Iupac: … {[(1S,2R,3R,4S,5S,6S)-2,3,5-trihydroxy-4,6-bis(phosphonooxy)cyclohexyl]oxy}phosphonic acid …
Matched Iupac: … {[(1S,2R,3R,4S,5S,6S)-2,3,5-trihydroxy-4,6-bis(phosphonooxy)cyclohexyl]oxy}phosphonic acid …
(-)-menthol 1-propylene glycol carbonate
Experimental
Matched Synonyms: … Carbonic acid, 2-hydroxypropyl (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester …
L-Acetylleucine
Investigational
Matched Synonyms: … (s)-2-acetamido-4-methylpentanoic acid …
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
Fimepinostat
Fimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.
Investigational
Matched Synonyms: … 5-pyrimidinecarboxamide, N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin ... N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and …
Futibatinib
Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and survival. FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed...
Approved
Investigational
Matched Synonyms: … 1-((3S)-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo(3, 4-d) pyrimidin-1-yl)-1-pyrrolidinyl) ... 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl] …
Matched Iupac: … 1-[(3S)-3-{4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl …
Matched Description: … of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and ... FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated ... FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 1-[(3S)-3-{4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl …
Matched Description: … of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and ... FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated ... FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Doxycycline
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Synonyms: … 6-alpha-deoxy-5-oxytetracycline …
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Salts name: … Doxycycline hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment ... Medications that reduce magnesium levels …
Matched Products: … LIEVRICIN-D ... Dom-doxycycline ... ORACEA ® CAPSULAS DE LIBERACION MODIFICADA …
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Salts name: … Doxycycline hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment ... Medications that reduce magnesium levels …
Matched Products: … LIEVRICIN-D ... Dom-doxycycline ... ORACEA ® CAPSULAS DE LIBERACION MODIFICADA …
Chlorphenesin carbamate
Approved
Vet approved
Withdrawn
Matched Synonyms: … carbamic acid 3-(p-chlorophenoxy)-2-hydroxypropyl ester …
Barzolvolimab
Barzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).
Investigational
Matched Synonyms: … Immunoglobulin G1 [233-alanine,234-glutamine,251-tyrosine,253-threonine,255-glutamic acid,321-glutamine ... ,de-C-terminal-lysine], anti-(human receptor tyrosine kinase KIT extracellular domain) (human-Mus musculus …
Dazodalibep
Dazodalibep is under investigation in clinical trial NCT06104124 (A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity).
Investigational
Matched Synonyms: … CD40 LIGAND-BINDING THIRD FIBRONECTIN TYPE III DOMAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 19-AMINO ACID …
Matched Description: … Dazodalibep is under investigation in clinical trial NCT06104124 (A Study to Evaluate the Efficacy and …
Matched Description: … Dazodalibep is under investigation in clinical trial NCT06104124 (A Study to Evaluate the Efficacy and …
Oseltamivir
Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Synonyms: … 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha …
Matched Description: … (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and ... prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. ... that early antiviral treatment can shorten the duration of fever and illness symptoms, and may reduce …
Matched Categories: … Acetates …
Matched Description: … (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and ... prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. ... that early antiviral treatment can shorten the duration of fever and illness symptoms, and may reduce …
Matched Categories: … Acetates …
Famciclovir
Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Synonyms: … acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester …
Matched Iupac: … 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor ... Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor …
Matched Products: … Dom-famciclovir …
Matched Iupac: … 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor ... Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor …
Matched Products: … Dom-famciclovir …
Diphenoxylate
A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act...
Approved
Illicit
Matched Synonyms: … 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl ester …
Matched Description: … Administration (FDA) and the DEA in the United States when used in preparations. ... Its unesterified metabolite difenoxin has similar properties and is used similarly. ... This medication is classified as a Schedule V under the Controlled Substances Act by the Food and Drug …
Matched Mixtures name: … Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Salts name: … Diphenoxylate hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Isonipecotic Acids …
Matched Description: … Administration (FDA) and the DEA in the United States when used in preparations. ... Its unesterified metabolite difenoxin has similar properties and is used similarly. ... This medication is classified as a Schedule V under the Controlled Substances Act by the Food and Drug …
Matched Mixtures name: … Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Salts name: … Diphenoxylate hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Isonipecotic Acids …
Inolimomab
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mirvetuximab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human folate receptor .alpha.) …
Entacapone
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Matched Synonyms: … (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide …
Matched Description: … and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased ... and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa …
Matched Mixtures name: … LEVODOPA/CARBIDOPA/ENTACAPONE DOC ... LEVODOPA/CARBIDOPA/ENTACAPONE DOC ... LEVODOPA/CARBIDOPA/ENTACAPONE DOC …
Matched Description: … and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased ... and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa …
Matched Mixtures name: … LEVODOPA/CARBIDOPA/ENTACAPONE DOC ... LEVODOPA/CARBIDOPA/ENTACAPONE DOC ... LEVODOPA/CARBIDOPA/ENTACAPONE DOC …
3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine
Experimental
Matched Name: … 3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine …
Matched Iupac: … 3-[(3-methoxyphenyl)methyl]-1H-pyrrolo[2,3-b]pyridine …
Matched Iupac: … 3-[(3-methoxyphenyl)methyl]-1H-pyrrolo[2,3-b]pyridine …
(3R)-4-(p-toluenesulfonyl)-1,4-thiazane-3-carboxylicacid-L-phenylalanine ethyl ester
Experimental
Matched Name: … (3R)-4-(p-toluenesulfonyl)-1,4-thiazane-3-carboxylicacid-L-phenylalanine ethyl ester …
Doxifluridine
Doxifluridine has been investigated for the treatment of Stomach Cancer.
Investigational
Matched Synonyms: … 1-(β-D-5-desoxyribofuranoxyl)-5-fluoruracil …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Fluorouracil and prodrugs …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Fluorouracil and prodrugs …
Xenon Xe-129
Hyperpolarized Xenon-129 (Xe-129) is a contrast agent used in the lung's clinical magnetic resonance imaging (MRI). Lung MRIs are challenging due to the low proton density of this tissue, as well as the presence of artifacts due to respiration and cardiovascular pulsation movement and air–tissue interfaces.[A255178,A255183] The use of hyperpolarized...
Approved
Matched Synonyms: … Xenon, isotope of mass 129m(8.88 d) …
Matched Description: … due to respiration and cardiovascular pulsation movement and air–tissue interfaces. ... [Helium-3] (He-3) is the one most commonly used due to its strong signal and favorable safety profile ... [A255178] Xe-129 has a lower cost, and adverse effects are normally resolved shortly after administration …
Matched Description: … due to respiration and cardiovascular pulsation movement and air–tissue interfaces. ... [Helium-3] (He-3) is the one most commonly used due to its strong signal and favorable safety profile ... [A255178] Xe-129 has a lower cost, and adverse effects are normally resolved shortly after administration …
BR101801
Experimental
Matched Synonyms: … 4-[[(1S)-1-(4,8-dichloro-1-oxo-2-phenylisoquinolin-3-yl)ethyl]amino]-8H-pyrido[2,3-d]pyrimidin-5-one …
BCX9250
Investigational
Matched Synonyms: … (S)-1-(4-(1-(3,4,5-trimethyloxyphenyl)-1H-imidazol-4-ylamino)thieno[2,3-d]pyrimidin-2-yl)pyrrolidine- …
Displaying drugs 3176 - 3200 of 3868 in total