Displaying drugs 3176 - 3200 of 4000 in total
Nicotinyl alcohol
A direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene. [PubChem]
Experimental
Matched Synonyms: … beta-pyridylcarbinol …
Matched Description: … A direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. ... It is used in vasospasm and threatened gangrene. [PubChem] …
Matched Categories: … Nicotinic Acid and Derivatives …
Matched Description: … A direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. ... It is used in vasospasm and threatened gangrene. [PubChem] …
Matched Categories: … Nicotinic Acid and Derivatives …
Clevudine
Investigational
Matched Synonyms: … 2'-Fluoro-5-methyl-beta-L-arabinofuranosyluracil …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Isoprenaline
Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160]
Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and …
Matched Mixtures name: … Duo-Medihaler …
Matched Salts name: … Isoprenaline hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases ... Adrenergic beta-Agonists ... Adrenergic beta-2 Receptor Agonists ... Non-selective Beta-adrenergic Agonists …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isoproterenol Hydrochloride Injection USP …
Matched Mixtures name: … Duo-Medihaler …
Matched Salts name: … Isoprenaline hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases ... Adrenergic beta-Agonists ... Adrenergic beta-2 Receptor Agonists ... Non-selective Beta-adrenergic Agonists …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isoproterenol Hydrochloride Injection USP …
Metoclopramide
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Description: … [L8417]
One unique property of this drug is that it does not increase gastric acid secretion. ... Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative ... impact on quality of life and poses a significant burden on the healthcare system. …
Matched Salts name: … Metoclopramide hydrochloride ... Metoclopramide hydrochloride anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Carboxylic Acids ... Dopamine D2 Receptor Antagonists …
Matched Products: … Metoclopramide Hydrochloride ... METOCLOPRAMIDE hydrochloride ... Metoclopramide hydrochloride …
Matched Salts name: … Metoclopramide hydrochloride ... Metoclopramide hydrochloride anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Carboxylic Acids ... Dopamine D2 Receptor Antagonists …
Matched Products: … Metoclopramide Hydrochloride ... METOCLOPRAMIDE hydrochloride ... Metoclopramide hydrochloride …
Meperidine
A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and …
Matched Mixtures name: … Meperidine Hydrochloride and Promethazine Hydrochloride ... Meperidine Hcl and Promethazine Hcl …
Matched Salts name: … Meperidine hydrochloride …
Matched Categories: … pethidine and antispasmodics ... Acids, Heterocyclic ... Isonipecotic Acids …
Matched Products: … DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml ... Meperidine Hydrochloride ... Meperidine Hydrochloride Injection USP …
Matched Mixtures name: … Meperidine Hydrochloride and Promethazine Hydrochloride ... Meperidine Hcl and Promethazine Hcl …
Matched Salts name: … Meperidine hydrochloride …
Matched Categories: … pethidine and antispasmodics ... Acids, Heterocyclic ... Isonipecotic Acids …
Matched Products: … DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml ... Meperidine Hydrochloride ... Meperidine Hydrochloride Injection USP …
Brimonidine
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Description: … [A178945] Thus brimonidine is an effective and safe alternative to beta-blockers, in patients with, or ... Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in ... Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular …
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Skin and Mucous Membrane Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Dom-brimonidine ... Alpha-Vision sine 2 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis ... TARTRATO DE BRIMONIDINA0.2 % …
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Skin and Mucous Membrane Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Dom-brimonidine ... Alpha-Vision sine 2 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis ... TARTRATO DE BRIMONIDINA0.2 % …
Taliglucerase alfa
Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase. It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Approved
Investigational
Matched Synonyms: … prGC-D …
Matched Description: … It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Ohmefentanyl
Ohmefentanyl is an extremely potent opioid analgesic drug which selectively binds to the µ-opioid receptor. The Chinese have recorded ohmefentanyl as having a potency that is 6,300 times morphine. Ohmefentanyl is one of the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and etorphine which...
Illicit
Matched Synonyms: … Beta-hydroxy-3-methylfentanyl …
Matched Description: … the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and ... In mice, ohmefentanyl was 28 times more powerful than fentanyl and 6300 times more effective than morphine ... Ohmefentanyl has three stereogenic centers and hence, it can derive into eight stereoisomers, currently …
Matched Description: … the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and ... In mice, ohmefentanyl was 28 times more powerful than fentanyl and 6300 times more effective than morphine ... Ohmefentanyl has three stereogenic centers and hence, it can derive into eight stereoisomers, currently …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid ... MPS VII is a progressive condition that affects most tissues and organs due to the lack of a lysosomal ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Lysosomal beta Glucuronidase …
Matched Description: … The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid ... MPS VII is a progressive condition that affects most tissues and organs due to the lack of a lysosomal ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Lysosomal beta Glucuronidase …
Ribaxamase
Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Investigational
Matched Synonyms: … .beta.-lactamase (synthetic bacillus licheniformis isoenzyme syn-004) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Naltrexone
Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Description: … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Naltrexone hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Matched Products: … Naltrexone Hydrochloride ... Naltrexone Hydrochloride Tablets USP …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Naltrexone hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Matched Products: … Naltrexone Hydrochloride ... Naltrexone Hydrochloride Tablets USP …
Tosyl-D-Proline
Experimental
Matched Name: … Tosyl-D-Proline …
Matched Iupac: … (2R)-1-(4-methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2R)-1-(4-methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid …
Finasteride
Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Description: … [A178159] In the treatment of benign prostate hyperplasia, alpha-blockers such as [tamsulosin] and [terazosin ... Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase ... by _in situ_ high levels of DHT. …
Matched Categories: … 5-alpha Reductase Inhibitors ... Adrenergic alpha-Antagonists ... Genito Urinary System and Sex Hormones ... Skin and Mucous Membrane Agents ... doxazosin and finasteride …
Matched Products: … FOLIX 1 MG TABLETAS ... Dom-finasteride ... FINASTERIDE DOC …
Matched Categories: … 5-alpha Reductase Inhibitors ... Adrenergic alpha-Antagonists ... Genito Urinary System and Sex Hormones ... Skin and Mucous Membrane Agents ... doxazosin and finasteride …
Matched Products: … FOLIX 1 MG TABLETAS ... Dom-finasteride ... FINASTERIDE DOC …
Flotegatide (18F)
Investigational
Matched Synonyms: … Cyclo(l-arginylglycyl-l-.alpha. ... -aspartyl-d-phenylalanyl-n6-(2,6-anhydro-7-deoxy-7-((2-(4-(3-(fluoro-18f)propyl)-1h-1,2,3-triazol-1-yl …
Cefatrizine
Experimental
Matched Iupac: … acetamido]-8-oxo-3-[(1H-1,2,3-triazol-4-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Thiazines ... beta-Lactams …
Matched Products: … ZINAF …
Matched Categories: … Thiazines ... beta-Lactams …
Matched Products: … ZINAF …
Noscapine
Approved
Investigational
Matched Synonyms: … alpha-Narcotine …
Matched Salts name: … Noscapine hydrochloride …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Matched Salts name: … Noscapine hydrochloride …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Etafedrine
Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin and Dalmacol . It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued .
Ethylephedrine is...
Approved
Matched Synonyms: … alpha-(1-(ethylmethylamino)ethyl)benzyl alcohol …
Matched Description: … It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. …
Matched Salts name: … Etafedrine hydrochloride …
Matched Categories: … Adrenergic beta-Agonists ... Adrenergic beta-2 Receptor Agonists …
Matched Description: … It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. …
Matched Salts name: … Etafedrine hydrochloride …
Matched Categories: … Adrenergic beta-Agonists ... Adrenergic beta-2 Receptor Agonists …
Calcium magnesium potassium carbonate chloride hydroxide
Experimental
Matched Name: … Calcium magnesium potassium carbonate chloride hydroxide …
Matched Iupac: … calcium magnesium(2+) dipotassium(2+) chloride trihydroxide carbonate …
Matched Iupac: … calcium magnesium(2+) dipotassium(2+) chloride trihydroxide carbonate …
6-[18F]-Fluoro-L-m-tyrosine
Investigational
Matched Synonyms: … (2s)-2-amino-3-(2-(18f)fluoranyl-5-hydroxyphenyl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-[2-(¹⁸F)fluoro-5-hydroxyphenyl]propanoic acid …
Matched Iupac: … (2S)-2-amino-3-[2-(¹⁸F)fluoro-5-hydroxyphenyl]propanoic acid …
AP-102
Investigational
Matched Synonyms: … H-(4-amino-3-iodo)-d-phe-c(cys-(3-iodo)-tyr-d-trp-lys-val-cys)-thr-nh2 ... H-(4-amino-3-iodo)-D-Phe-c[Cys-(3-iodo)-Tyr-D-Trp-Lys-Val-Cys]-Thr-NH2 ... L-threoninamide, 4-amino-3-iodo-d-phenylalanyl-l-cysteinyl-3-iodo-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl-l-cysteinyl …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
[4-(4-Hydroxy-Benzyl)-2-(2-Hydroxy-1-Methyl-Ethyl)-5-Oxo-Imidazolidin-1-Yl]-Acetic Acid
Experimental
Matched Name: … [4-(4-Hydroxy-Benzyl)-2-(2-Hydroxy-1-Methyl-Ethyl)-5-Oxo-Imidazolidin-1-Yl]-Acetic Acid …
Matched Iupac: … -1-amino-2-hydroxyethyl]-4-[(4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid …
Matched Iupac: … -1-amino-2-hydroxyethyl]-4-[(4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid …
2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide
Experimental
Matched Name: … 2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl …
3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID
Experimental
Matched Name: … 3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID …
Matched Iupac: … 3-{9-hydroxy-1,3-dioxo-4-phenyl-1H,2H,3H,6H-pyrrolo[3,4-c]carbazol-6-yl}propanoic acid …
Matched Iupac: … 3-{9-hydroxy-1,3-dioxo-4-phenyl-1H,2H,3H,6H-pyrrolo[3,4-c]carbazol-6-yl}propanoic acid …
2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID
Experimental
Matched Name: … DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID …
Matched Iupac: … dimethylamino)prop-1-en-1-yl]-4-fluorobenzenesulfonamido}-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid …
Matched Iupac: … dimethylamino)prop-1-en-1-yl]-4-fluorobenzenesulfonamido}-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid …
1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID
Experimental
Matched Name: … 1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID …
Matched Iupac: … -{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-2-(3-cyanophenyl)ethyl]boronic acid …
Matched Iupac: … -{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-2-(3-cyanophenyl)ethyl]boronic acid …
Displaying drugs 3176 - 3200 of 4000 in total