Displaying drugs 301 - 325 of 13578 in total
Lovastatin
Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Synonyms: … -2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate ... 2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone ... (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran …
Matched Iupac: … -1-yl (2S)-2-methylbutanoate ... (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen …
Matched Description: … moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction ... derived synthetically from a fermentation product of _Aspergillus terreus_. …
Matched Iupac: … -1-yl (2S)-2-methylbutanoate ... (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen …
Matched Description: … moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction ... derived synthetically from a fermentation product of _Aspergillus terreus_. …
Iothalamic acid
Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Approved
Matched Synonyms: … 1-deoxy-1-(methylamino)-D-glucitol 5-acetamido-2,4,6 triiodo-N-methylisophthalamate …
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid …
Matched Description: … Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent. …
Matched Salts cas: … 1225-20-3 ... 13087-53-1 ... 17692-74-9 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid …
Matched Description: … Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent. …
Matched Salts cas: … 1225-20-3 ... 13087-53-1 ... 17692-74-9 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Memantine
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Synonyms: … 1-Amino-3,5-dimethyladamantane ... 3,5-Dimethyl-1-adamantanamine ... 3,5-Dimethyl-1-aminoadamantane …
Matched Iupac: … 3,5-dimethyladamantan-1-amine …
Matched Description: … Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist ... In 2010, it was estimated that 36 million people worldwide live with Alzheimer's Disease. ... with the objective of developing a cure or a disease-modifying therapy by the year 2025 [L5953, F4366 …
Matched Salts cas: … 41100-52-1 …
Matched Categories: … N-methyl-D-aspartate Receptor Antagonist …
Matched Iupac: … 3,5-dimethyladamantan-1-amine …
Matched Description: … Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist ... In 2010, it was estimated that 36 million people worldwide live with Alzheimer's Disease. ... with the objective of developing a cure or a disease-modifying therapy by the year 2025 [L5953, F4366 …
Matched Salts cas: … 41100-52-1 …
Matched Categories: … N-methyl-D-aspartate Receptor Antagonist …
Latanoprost
Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Synonyms: … propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate ... isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate …
Matched Iupac: … propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate …
Matched Description: … Another benefit latanoprost is that it can be administered once a day.[A184490] ... Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular …
Matched Mixtures name: … DUOPROST GÖZ DAMLASI, 1 ADET ... LATAMED %0.005+%0.5 GÖZ DAMLASI, 1 ADET ... LATROST-T %0,005+%0,5 GÖZ DAMLASI, ÇÖZELTİ, 2,5 ML 1 ŞİŞE …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … LATASOPT % 0.005 GÖZ DAMLASI ,2.5 ML,1 ŞIŞE …
Matched Iupac: … propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate …
Matched Description: … Another benefit latanoprost is that it can be administered once a day.[A184490] ... Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular …
Matched Mixtures name: … DUOPROST GÖZ DAMLASI, 1 ADET ... LATAMED %0.005+%0.5 GÖZ DAMLASI, 1 ADET ... LATROST-T %0,005+%0,5 GÖZ DAMLASI, ÇÖZELTİ, 2,5 ML 1 ŞİŞE …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … LATASOPT % 0.005 GÖZ DAMLASI ,2.5 ML,1 ŞIŞE …
Ketoconazole
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Iupac: … 1-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin ... -1-yl]ethan-1-one …
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [A188054] At this time it was considered a significant improvement over previous antifungals, [miconazole …
Matched Mixtures name: … Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2% ... Ketoconazole 2% / Salicylic Acid 2% ... Ketoconazole 2% / Niacinamide 4% …
Matched Products: … Nizoral A-D ... A-BE LOTION ... KETORAL 400 MG VAJİNAL SUPOZİTUVAR, 3 ADET …
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [A188054] At this time it was considered a significant improvement over previous antifungals, [miconazole …
Matched Mixtures name: … Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2% ... Ketoconazole 2% / Salicylic Acid 2% ... Ketoconazole 2% / Niacinamide 4% …
Matched Products: … Nizoral A-D ... A-BE LOTION ... KETORAL 400 MG VAJİNAL SUPOZİTUVAR, 3 ADET …
Drotaverine
Drotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). It is a benzylisoquinoline derivative that is structurally related to papaverine, although it displays more potent antispasmodic activities than papaverine. Drotaverine has been used in the symptomatic treatment of various spastic conditions, such as gastrointestinal diseases, biliary dyskinesia, and...
Approved
Investigational
Matched Iupac: … (1Z)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline …
Matched Description: … [A231619] It is a benzylisoquinoline derivative that is structurally related to [papaverine], although ... drotaverine gained attention in the treatment of benign prostatic hyperplasia, parainfluenza, and avian influenza …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … [A231619] It is a benzylisoquinoline derivative that is structurally related to [papaverine], although ... drotaverine gained attention in the treatment of benign prostatic hyperplasia, parainfluenza, and avian influenza …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Hydralazine
Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Synonyms: … 1-Hydrazinophthalazine ... 1-Phthalazinylhydrazine ... Phthalazin-1-ylhydrazine …
Matched Iupac: … 1-hydrazinylphthalazine …
Matched Description: … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability ... [A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment ... [A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development …
Matched Salts cas: … 304-20-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-hydrazinylphthalazine …
Matched Description: … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability ... [A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment ... [A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development …
Matched Salts cas: … 304-20-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Leuprolide
Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched International brands: … Prostap 3 …
Matched Iupac: … (2S)-1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol ... -3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine ... -4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido] ... -2-carboxamide …
Matched Description: … Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). ... Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing …
Matched Products: … LUCRIN DEPOT-3 M 11,25 IM/SC ENJEKSIYONLUK FLAKON, 1 ADET ... LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE ... LUCRIN 3 MONTH DEPOT, 11.25MG SUSPENSION …
Matched Iupac: … (2S)-1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol ... -3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine ... -4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido] ... -2-carboxamide …
Matched Description: … Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). ... Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing …
Matched Products: … LUCRIN DEPOT-3 M 11,25 IM/SC ENJEKSIYONLUK FLAKON, 1 ADET ... LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE ... LUCRIN 3 MONTH DEPOT, 11.25MG SUSPENSION …
Heparin
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … It is a naturally occurring anticoagulant released from mast cells. ... Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers ... infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a …
Matched Mixtures name: … BARICUS 50 IU/%1/%10 JEL , 50 G …
Matched Products: … THROMBOCUTAN 30000IE GEL N ... THROMBOCUTAN 30000IE SAL N ... B. BRAUN HEPARINISED SALINE 10IU/ML SOLUTION FOR INJECTION …
Matched Mixtures name: … BARICUS 50 IU/%1/%10 JEL , 50 G …
Matched Products: … THROMBOCUTAN 30000IE GEL N ... THROMBOCUTAN 30000IE SAL N ... B. BRAUN HEPARINISED SALINE 10IU/ML SOLUTION FOR INJECTION …
Glutamic acid
A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Synonyms: … (2S)-2-Aminopentanedioic acid ... (S)-2-Aminopentanedioic acid …
Matched Iupac: … (2S)-2-aminopentanedioic acid …
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … Vamin N ... Numeta G 16 % E Emulsion zur Infusion ... AMINOPLASMAL® B. BRAUN 10% …
Matched Iupac: … (2S)-2-aminopentanedioic acid …
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … Vamin N ... Numeta G 16 % E Emulsion zur Infusion ... AMINOPLASMAL® B. BRAUN 10% …
Betahistine
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408]
Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … N-methyl-2-(2-pyridinyl)ethanamine ... N-methyl-2-pyridineethanamine ... [2-(2-pyridyl)ethyl]methylamine …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … It has a significant impact on both the physical and social functioning of affected individuals. ... Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... [A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … BETAVERT N 8MG ... BETAVERT N 16MG ... BETAVERT N 24MG …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … It has a significant impact on both the physical and social functioning of affected individuals. ... Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... [A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … BETAVERT N 8MG ... BETAVERT N 16MG ... BETAVERT N 24MG …
Dalfampridine
Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Approved
Matched Description: … FDA approved on January 22, 2010. ... Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... OCT2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... OCT2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Arbutamine
Arbutamine, administered through a closed-loop, computer-controlled drug-delivery system, is indicated to elicit acute cardiovascular responses, similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease in patients who cannot exercise adequately .
Approved
Matched Iupac: … 4-[(1R)-1-hydroxy-2-{[4-(4-hydroxyphenyl)butyl]amino}ethyl]benzene-1,2-diol …
Matched Description: … Arbutamine, administered through a closed-loop, computer-controlled drug-delivery system, is indicated …
Matched Salts cas: … 125251-66-3 …
Matched Categories: … Adrenergic beta-1 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists ... Adrenergic beta-3 Receptor Agonists ... Compounds used in a research, industrial, or household setting …
Matched Description: … Arbutamine, administered through a closed-loop, computer-controlled drug-delivery system, is indicated …
Matched Salts cas: … 125251-66-3 …
Matched Categories: … Adrenergic beta-1 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists ... Adrenergic beta-3 Receptor Agonists ... Compounds used in a research, industrial, or household setting …
Sotalol
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Synonyms: … 4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide …
Matched Iupac: … N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide …
Matched Description: … [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous ... Sotalol is a methanesulfonanilide developed in 1960. …
Matched Categories: … Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide …
Matched Description: … [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous ... Sotalol is a methanesulfonanilide developed in 1960. …
Matched Categories: … Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Tetryzoline
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Synonyms: … 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline ... 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole ... (RS)-2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Iupac: … 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Description: … [A231769] Available since the 1950s, tetryzoline is a selective α1-receptor agonist [A231774 ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... Tetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, …
Matched Mixtures name: … Murine Tears Plus 3 ... ISCHEMOL A ... ISCHEMOL A …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Adrenergic alpha-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Murine Plus 2 ... OPHTALMIN N ... BERBERIL N EDO …
Matched Iupac: … 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Description: … [A231769] Available since the 1950s, tetryzoline is a selective α1-receptor agonist [A231774 ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... Tetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, …
Matched Mixtures name: … Murine Tears Plus 3 ... ISCHEMOL A ... ISCHEMOL A …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Adrenergic alpha-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Murine Plus 2 ... OPHTALMIN N ... BERBERIL N EDO …
Daprodustat
Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Synonyms: … Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)- …
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid …
Matched Description: … [A254157] A phase 3 clinical trial (NCT02879305) found that in patients with CKD undergoing dialysis, ... [L43857] On February 1, 2023, daprodustat was fully approved by the FDA as the first oral treatment for ... Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid …
Matched Description: … [A254157] A phase 3 clinical trial (NCT02879305) found that in patients with CKD undergoing dialysis, ... [L43857] On February 1, 2023, daprodustat was fully approved by the FDA as the first oral treatment for ... Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bulevirtide
Hepatitis D is considered the most severe type of viral hepatitis and leads to the rapid development of cirrhosis, severe decompensation of liver function, and an increased risk of mortality.[A226340,L30235] Until recently, there have been extremely limited treatments available for Hepatitis D infection. Bulevirtide, also known as Hepcludex, is a...
Approved
Investigational
Matched International brands: … Myrcludex B …
Matched Description: … [A226305] Bulevirtide, also known as Hepcludex, is a first-in-class entry inhibitor for the treatment …
Matched Description: … [A226305] Bulevirtide, also known as Hepcludex, is a first-in-class entry inhibitor for the treatment …
Isoniazid
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Description: … Antibacterial agent used primarily as a tuberculostatic. …
Matched Mixtures name: … Isotamine B 300 ... PRO TB 3 KID ... RIFAMPICIN 75 MG / ISONIAZID 50 MG (FDC 2 ANAK) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Mixtures name: … Isotamine B 300 ... PRO TB 3 KID ... RIFAMPICIN 75 MG / ISONIAZID 50 MG (FDC 2 ANAK) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ferrous gluconate
Approved
Matched Synonyms: … Iron(2+) gluconate (1:2) ... D-gluconic acid, iron(2+) salt (2:1) …
Matched Iupac: … lambda2-iron(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Mixtures name: … Swical-energy-2 ... Vitamine Du Groupe B Plus Fer - Liq ... Vege 1 Daily Tab …
Matched Iupac: … lambda2-iron(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Mixtures name: … Swical-energy-2 ... Vitamine Du Groupe B Plus Fer - Liq ... Vege 1 Daily Tab …
Dacomitinib
Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Matched Iupac: … (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide …
Matched Description: … Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Human interferon beta
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Description: … results from infection with the novel 2019 SARS-CoV-2 virus. ... It is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity. ... the past in clinical studies with other coronaviruses due to its demonstrated activity against the virus …
Acebutolol
A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Approved
Investigational
Matched Synonyms: … N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide ... N-(3-acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide ... 5'-butyramido-2'-(2-hydroxy-3-isopropylaminopropoxy)acetophenone …
Matched Iupac: … N-(3-acetyl-4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)butanamide …
Matched Description: … A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Matched Iupac: … N-(3-acetyl-4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)butanamide …
Matched Description: … A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Ansuvimab
Infection with pathogenic filoviruses, such as Zaire ebolavirus (Ebola virus, EBOV), can cause severe hemorrhagic fever in humans, resulting in frequent outbreaks with case fatality rates as high as 90%.[A225933, A225938] Virtually all steps of the EBOV lifecycle have been targeted for therapeutic development. However, to date, the most successful...
Approved
Investigational
Matched Description: … virus disease (EVD) in the Democratic Republic of Congo during a previous outbreak that began in 2018 ... Infection with pathogenic filoviruses, such as _Zaire ebolavirus_ (Ebola virus, EBOV), can cause severe ... [A225933] Ansuvimab, formerly mAb114, is a fully human IgG1 mAb derived from a survivor of the 1995 Kikwit …
Matched Categories: … Treatments for Ebola Virus Disease …
Matched Categories: … Treatments for Ebola Virus Disease …
Fosaprepitant
Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Approved
Matched Iupac: … (3-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl ... }-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid …
Matched Description: … It is a prodrug of Aprepitant. …
Matched Categories: … Neurokinin 1 Antagonists ... Heterocyclic Compounds, 1-Ring ... Neurokinin-1 Receptor Antagonists ... Substance P/Neurokinin-1 Receptor Antagonist …
Matched Products: … APRITANT IV® 150 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET ... İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET …
Matched Description: … It is a prodrug of Aprepitant. …
Matched Categories: … Neurokinin 1 Antagonists ... Heterocyclic Compounds, 1-Ring ... Neurokinin-1 Receptor Antagonists ... Substance P/Neurokinin-1 Receptor Antagonist …
Matched Products: … APRITANT IV® 150 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET ... İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET …
Nalbuphine
A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Synonyms: … N-cyclobutylmethyl-4,5α-epoxy-3,6α,14-morphinantriol …
Matched Description: … A narcotic used as a pain medication. ... Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States. …
Matched Salts cas: … 23277-43-2 …
Matched Description: … A narcotic used as a pain medication. ... Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States. …
Matched Salts cas: … 23277-43-2 …
Displaying drugs 301 - 325 of 13578 in total