Displaying drugs 3326 - 3350 of 3982 in total
Inecalcitol
Investigational
APD-209
Investigational
NVS antibody
This drug has been developed using Medarex's UltiMAb Human Antibody Development System to treat autoimmune diseases.
Investigational
Matched Description: … This drug has been developed using Medarex's UltiMAb Human Antibody Development System to treat autoimmune …
GLPG-0492
Glpg0492 is under investigation in clinical trial NCT01130818 (First-in-Human Single Ascending Dose of GLPG0492).
Investigational
Matched Description: … Glpg0492 is under investigation in clinical trial NCT01130818 (First-in-Human Single Ascending Dose of …
SB 224289
SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.
Investigational
Matched Description: … SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122] …
ZM-39923
ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2).
Investigational
Matched Description: … ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2). …
Pegozafermin
Pegozafermin is under investigation in clinical trial NCT05852431 (To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia).
Investigational
GIVI-MPC
GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells.
Investigational
Matched Description: … GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells …
Tianeptine
Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) . Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants .
Tianeptine was discovered and...
Investigational
Matched Iupac: … 7-({6-chloro-10-methyl-9,9-dioxo-9lambda6-thia-10-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13 …
Natural Killer Cell
Natural Killer (NK) cells originate and differentiate from hematopoietic stem cells through various signalling pathways involving cytokines and interleukins. These cells arise from CD34+ lymphoid progenitors and comprise 10-15% of all lymphocytes in human peripheral blood. Once completely differentiated, NK cells lack B (CD19-) and T(CD3-) lymphocyte markers and carry...
Investigational
Matched Description: … These cells arise from CD34+ lymphoid progenitors and comprise 10-15% of all lymphocytes in human peripheral ... Induced pluripotent stem cells (iPSCs) and human embryonic stem cells (HESCs) are also used to generate …
jCell
jCell is an human retinal progenitor cell therapy for retinitis pigmentosa.
Investigational
Matched Description: … jCell is an human retinal progenitor cell therapy for retinitis pigmentosa. …
AG-858
AG-858 (autologous heat-shock protein 70 peptide vaccine) is
a recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing. Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity...
Investigational
Matched Description: … AG-858 (autologous heat-shock protein 70 peptide vaccine) is
a recombinant cancer vaccine made with …
Butyrylcholinesterase
Investigational
Mequitazine
Mequitazine is a histamine H1 antagonist (antihistamine). It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory...
Experimental
Matched Iupac: … 10-({1-azabicyclo[2.2.2]octan-3-yl}methyl)-10H-phenothiazine …
Dimethylaminopropionylphenothiazine
Experimental
Matched Iupac: … 2-(dimethylamino)-1-(10H-phenothiazin-10-yl)propan-1-one …
JNJ-27390467
JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase.
Experimental
Matched Description: … JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase. …
Tosedostat
Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others.
Tosedostat is an inhibitor of the M1 family of aminopeptidases, in particular PuSA, and LTA4 hydrolase. It has demonstrated anti-tumour activity in a number of models...
Investigational
AVP-21D9
AVP-21D9 is a fully human anthrax monoclonal antibody that is being investigated as an anthrax antitoxin.
Investigational
Matched Description: … AVP-21D9 is a fully human anthrax monoclonal antibody that is being investigated as an anthrax antitoxin …
MRT5005
MRT5005 is a human cystic fibrosis transmembrane conductance regulator (hCFTR) messenger RNA (mRNA) complexed with branched polyethyleneimine (bPEI).
Investigational
Matched Description: … MRT5005 is a human cystic fibrosis transmembrane conductance regulator (hCFTR) messenger RNA (mRNA) complexed …
C134
C134 is a genetically engineered oncolytic herpes simplex virus expressing human cytomegalovirus (HCMV) internal repeat short 1 (IRS1).
Investigational
Matched Description: … C134 is a genetically engineered oncolytic herpes simplex virus expressing human cytomegalovirus (HCMV …
FCX-013
FCX-013 consists of human dermal fibroblasts genetically modified with a lentiviral vector expressing metalloproteinase-1 (MMP-1).
Investigational
Matched Description: … FCX-013 consists of human dermal fibroblasts genetically modified with a lentiviral vector expressing …
hu3S193
Investigational
Indium In-111 satumomab pendetide
Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available.
Experimental
Withdrawn
Displaying drugs 3326 - 3350 of 3982 in total