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Displaying drugs 351 - 375 of 9975 in total
Sulconazole
Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution. Sulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an effective treatment for tinea cruris and tinea corporis infections.[L44592,L44597] Sulconazole appears to be effective...
Approved
Matched Iupac: … 1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Regadenoson
Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Iupac: … 1-{6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-2-yl}-N-methyl-1H-pyrazole …
Matched Salts cas: … 875148-45-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 875148-45-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Sutimlimab
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Synonyms: … Humanized IgG4 monoclonal antibody against total complement component 1, subcomponent s …
Influenza A virus A/Singapore/gp1908/2015 IVR-180 (H1N1) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Emtricitabine
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Synonyms: … (−)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one ... (2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone ... 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one …
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Description: … [L9019] Emtricitabine was granted FDA approval on 2 July 2003.[L9019] ... of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Description: … [L9019] Emtricitabine was granted FDA approval on 2 July 2003.[L9019] ... of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Oteracil
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Salts cas: … 2207-75-2 …
Matched Mixtures name: … TS ONE OD Tablet 20 ... TS-ONE Capsule 20 ... TS-ONE CAPSULE 20 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 2207-75-2 …
Matched Mixtures name: … TS ONE OD Tablet 20 ... TS-ONE Capsule 20 ... TS-ONE CAPSULE 20 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dihydrotachysterol
A vitamin D that can be regarded as a reduction product of vitamin D2.
Approved
Matched Iupac: … (1S,3E,4S)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden ... -4-ylidene]ethylidene}-4-methylcyclohexan-1-ol …
Betahistine
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408]
Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … [2-(2-pyridyl)ethyl]methylamine ... 2-[2-(methylamino)ethyl]pyridine ... N-methyl-2-(2-pyridinyl)ethanamine …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … BETARİS 24 MG TABLET, 20 ADET ... BETASERC 24 MG TABLET, 20 ADET …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … BETARİS 24 MG TABLET, 20 ADET ... BETASERC 24 MG TABLET, 20 ADET …
Adalimumab
Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor.[A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. This drug is frequently known as Humira. It is produced...
Approved
Experimental
Matched Products: … AMGEVİTA 20 MG/0.4 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... HUMİRA 20 MG/0,2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET ... AMGEVITA 20 mg/0.4 ml solution for injection in pre-filled syringe …
Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Products: … ACT-HIB 0,5ML IM/SC 1 FLK LIYOFILIZE ASI+1 ENJ. COZUCU …
Methenamine
Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Approved
Vet approved
Matched Salts cas: … 24360-05-2 ... 72962-48-2 …
Matched Mixtures name: … Me NaPhos MB Hyo 1 …
Matched Products: … HIPPURIN 1 GR FILM TABLET, 56 ADET ... HIPPURIN 1 GR FILM TABLET, 28 ADET …
Matched Mixtures name: … Me NaPhos MB Hyo 1 …
Matched Products: … HIPPURIN 1 GR FILM TABLET, 56 ADET ... HIPPURIN 1 GR FILM TABLET, 28 ADET …
Influenza A Virus A/California/122/2022 SAN-022 (H3N2) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Sibutramine
Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the...
Approved
Illicit
Investigational
Withdrawn
Matched Iupac: … {1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}dimethylamine …
Matched Products: … SEROTRAMIN CAPSULAS 20 MG. …
Matched Products: … SEROTRAMIN CAPSULAS 20 MG. …
Methadone
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Products: … Methasan 2 mg/ml-Sirup ... Methasan 20 mg-Tabletten …
Papaverine
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Iupac: … 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline …
Matched Salts cas: … 2053-26-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … PAPAVERINE HCL 60 MG TABLET, 20 ADET ... PAPAVERIN HIDROKLORUR 0.04 G/2 ML BIOSEL AMPUL, 10 ADET ... PAPAVERIN HIDROKLORUR 0.05 G/2 ML BIOSEL AMPUL, 10 ADET …
Matched Salts cas: … 2053-26-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … PAPAVERINE HCL 60 MG TABLET, 20 ADET ... PAPAVERIN HIDROKLORUR 0.04 G/2 ML BIOSEL AMPUL, 10 ADET ... PAPAVERIN HIDROKLORUR 0.05 G/2 ML BIOSEL AMPUL, 10 ADET …
Fenofibric acid
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Iupac: … 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid …
Matched Mixtures name: … FENOVAS®20 MG ... STAFEN® 135 / 20 MG CAPSULA ... STAFEN® 135 / 20 MG CAPSULA …
Matched Mixtures name: … FENOVAS®20 MG ... STAFEN® 135 / 20 MG CAPSULA ... STAFEN® 135 / 20 MG CAPSULA …
Omaveloxolone
Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory properties.[A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity...
Approved
Investigational
Matched Synonyms: … Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro- …
Matched Description: … [A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 ( …
Matched Description: … [A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 ( …
Meprednisone
Approved
Investigational
Matched Iupac: … (1S,2R,10S,11S,13S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵ …
Secnidazole
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Synonyms: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2 ol ... 1-(2 hydroxypropyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SECNIZOL® 2 G ... SECNIDOX 1000 MG FILM TABLET,2 ADET ... SECNIDOX 500 MG FILM TABLET ,2 FILM TABLET …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SECNIZOL® 2 G ... SECNIDOX 1000 MG FILM TABLET,2 ADET ... SECNIDOX 500 MG FILM TABLET ,2 FILM TABLET …
Methylprednisone
Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Approved
Investigational
Matched Iupac: … (1R,3aS,3bS,5S,9aR,9bS,11aS)-1-hydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H, …
Chymotrypsin
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...
Approved
Vet approved
Matched Description: … Chymotrypsin is the most abundant pancreatic proteases that represent up to 10-20% of the total protein …
Imiquimod
Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that...
Approved
Investigational
Matched Synonyms: … 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine ... 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline …
Matched Iupac: … 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine …
Matched Description: … Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. …
Matched Mixtures name: … Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2% ... Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Tretinoin 0.05% …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … QUIMARA-1 …
Matched Iupac: … 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine …
Matched Description: … Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. …
Matched Mixtures name: … Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2% ... Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Tretinoin 0.05% …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … QUIMARA-1 …
Indocyanine green acid form
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Iupac: … 2-{7-[1,1-dimethyl-3-(4-sulfobutyl)-1H,2H,3H-benzo[e]indol-2-ylidene]hepta-1,3,5-trien-1-yl}-1,1-dimethyl …
Matched Description: … The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl ... )-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl ... )-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Doripenem
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Iupac: … yl]sulfanyl}-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-{[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3- …
Matched Salts cas: … 364622-82-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 364622-82-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Influenza B virus B/Maryland/15/2016 BX-69A antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Mixtures name: … VAXİGRİP TETRA 0,5 ML IM/SC ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR , 1 ADET …
Displaying drugs 351 - 375 of 9975 in total