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Displaying drugs 3726 - 3750 of 8030 in total
Investigational
Matched Synonyms: … 72 amino acid proprietary recombinant protein antagonist for the CXCR1 and CXCR2 receptors of interleukin …
AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Synonyms: … serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/MFSD8 gene for expression of
Matched Description: … It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. ... serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … AN AVERAGE OF 4 TO ... (1-447)-PEPTIDE), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA, SUBSTITUTED ON N6 OF
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single …
AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA (siRNA).
Investigational
Matched Synonyms: … an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 …
AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … vector (LV)-mediated, genetically modified autologous cell therapy intended for the stable provision of
Matched Description: … It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII) …
Technetium-99m is the metastable isotope of technetium. It is commonly symbolized as 99mTc and used in the area of medical diagnosis. Technetium-99m is the most commonly used medical radioisotope.
Experimental
Matched Synonyms: … Technetium, isotope of mass 99 …
Matched Description: … Technetium-99m is the metastable isotope of technetium. ... It is commonly symbolized as 99mTc and used in the area of medical diagnosis. …
AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide targeting DUX4.
Investigational
Matched Synonyms: … An antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector …
Matched Description: … AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting …
scAAV9.U7.ACCA is a non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding RNA. Developed by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular dystrophy.
Investigational
Matched Synonyms: … containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of
Matched Description: … containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of ... Developed by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular …
AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
Matched Synonyms: … Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid- …
IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Matched Synonyms: … Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic …
Matched Description: … It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a …
Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency.
Investigational
Matched Synonyms: … HUMAN SERUM ALBUMIN FUSED TO THE N-TERMINUS OF GROWTH HORMONE …
Matched Description: … Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth …
Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study in Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)).
Investigational
Matched Synonyms: … Engineered variant of recombinant human fibroblast growth factor 19 …
Matched Description: … Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability ... of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study in Subjects …
Investigational
Matched Synonyms: … adenovirus delta 24-RGD, an oncolytic adenovirus genetically modified for treatment of glioma …
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal …
Matched Description: … DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants …
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
Investigational
Matched Synonyms: … AUTOLOGOUS CD34+ CELLS ISOLATED FROM BONE MARROW OF NEWLY DIAGNOSED X-LINKED SEVERE COMBINED IMMUNODEFICIENCY …
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form of
Matched Description: … using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of
Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Synonyms: … F-652 (RECOMBINANT FUSION PROTEIN CONSISTING OF TWO HUMAN INTERLEUKIN-22 (IL-22) MOLECULES LINKED TO …
Matched Description: … a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of
Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable …
PCO-371 is under investigation in clinical trial NCT02475616 (A Single Ascending Dose Study of PCO371 in Healthy Volunteers).
Investigational
Matched Synonyms: … non-peptide small molecule orally available agonist of the parathyroid hormone receptor type I …
Matched Description: … PCO-371 is under investigation in clinical trial NCT02475616 (A Single Ascending Dose Study of PCO371 …
Whey allergenic extract is used in allergenic testing.
Investigational
Matched Synonyms: … Whey Protein Component Of Ultracur …
Investigational
Matched Synonyms: … Recombinant, soluble, non-glycosylated version of fc gamma receptor iib …
Investigational
Matched Synonyms: … Allogeneic umbilical cord blood (UCB) cell therapy product consisting of two cell fractions (CD34 enriched …
Investigational
Matched Synonyms: … Active principle of the pars intermedia of the pituitary …
Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational
Matched Synonyms: … Recombinant fusion protein of Mycobacterium bovis BCG Hsp65 and HPV16 E7 …
Matched Description: … Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be ... used to design vaccines against a number of different cancers. ... Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from …
Displaying drugs 3726 - 3750 of 8030 in total