Displaying drugs 3751 - 3775 of 5775 in total
Cobicistat
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate …
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and ... any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A …
Matched Mixtures name: … REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADET ... GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 30 ADET ... STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 30 ADET …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and ... any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A …
Matched Mixtures name: … REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADET ... GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 30 ADET ... STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 30 ADET …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances …
Tamoxifen
Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Synonyms: … 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene ... 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene …
Matched Description: … treatment for these types of cancers as patients generally have better survival, side effect profiles, and ... [A1026] Tamoxifen was granted FDA approval on 30 December 1977.[L7799] …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Medications that reduce magnesium levels …
Matched Products: … TAMOXIFEN AL 30 ... TADEX 10 MG TABLET, 30 ADET ... TAMOXEN 20 MG TABLET, 30 ADET …
Matched Description: … treatment for these types of cancers as patients generally have better survival, side effect profiles, and ... [A1026] Tamoxifen was granted FDA approval on 30 December 1977.[L7799] …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Medications that reduce magnesium levels …
Matched Products: … TAMOXIFEN AL 30 ... TADEX 10 MG TABLET, 30 ADET ... TAMOXEN 20 MG TABLET, 30 ADET …
Pelareorep
Investigational
Matched Synonyms: … Reovirus type 3 (strain dearing) (t3d) (mammalian orthoreovirus 3) ... Reovirus 3 (strain dearing) ... Mammalian orthoreovirus 3-dearing …
Divarasib
Investigational
Matched Synonyms: … 2-propen-1-one, 1-((3S)-4-((7R)-7-(6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl)-6-chloro-8-fluoro ... 1-((3S)-4-((7M)-7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((2S)-1-methylpyrrolidin ... -2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one …
Idoxuridine
An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Approved
Investigational
Matched Synonyms: … 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil ... 1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracil …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Peresolimab
Peresolimab is under investigation in clinical trial NCT04634253 (A Study of LY3462817 in Participants With Rheumatoid Arthritis).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human programmed cell death protein 1) (human monoclonal ly3462817 .gamma.1- …
Peptide YY (3-36)
Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity. It reduces appetite and increases satiety in obese patients.
Investigational
Matched Synonyms: … PYY 3-36 ... PYY(3-36) ... Pyy (3-36) peptide …
Matched Name: … Peptide YY (3-36) …
Matched Description: … It reduces appetite and increases satiety in obese patients. ... Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Peptide YY (3-36) …
Matched Description: … It reduces appetite and increases satiety in obese patients. ... Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Doxycycline
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Synonyms: … 6-alpha-deoxy-5-oxytetracycline …
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Mixtures name: … BenzoDox 30 Kit ... BenoxylDoxy 30 Kit …
Matched Salts name: … Doxycycline hydrochloride ... Doxycycline calcium …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment ... Medications that reduce magnesium levels …
Matched Products: … Vibramycin Calcium …
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Mixtures name: … BenzoDox 30 Kit ... BenoxylDoxy 30 Kit …
Matched Salts name: … Doxycycline hydrochloride ... Doxycycline calcium …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment ... Medications that reduce magnesium levels …
Matched Products: … Vibramycin Calcium …
3-Methylphenylalanine
Experimental
Matched Name: … 3-Methylphenylalanine …
Matched Iupac: … (2S)-2-amino-3-(3-methylphenyl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(3-methylphenyl)propanoic acid …
3'-deoxyguanosine
3'-deoxyguanosine is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. This medication targets the protein purine nucleoside phosphorylase.
Experimental
Matched Name: … 3'-deoxyguanosine …
Matched Iupac: … 2-amino-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … 3'-deoxyguanosine is a solid. This compound belongs to the purine nucleosides and analogues. ... This medication targets the protein purine nucleoside phosphorylase. …
Matched Iupac: … 2-amino-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … 3'-deoxyguanosine is a solid. This compound belongs to the purine nucleosides and analogues. ... This medication targets the protein purine nucleoside phosphorylase. …
3-Dehydroshikimate
Experimental
Matched Name: … 3-Dehydroshikimate …
Matched Iupac: … (4S,5R)-4,5-dihydroxy-3-oxocyclohex-1-ene-1-carboxylic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic ... Hydroxy Acids ... Cyclohexanecarboxylic Acids …
Matched Iupac: … (4S,5R)-4,5-dihydroxy-3-oxocyclohex-1-ene-1-carboxylic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic ... Hydroxy Acids ... Cyclohexanecarboxylic Acids …
3-Phenylpropylamine
Experimental
Matched Synonyms: … 3-phenylpropanamine ... 3-phenyl-1-aminopropane ... 3-phenyl-1-propylamine …
Matched Name: … 3-Phenylpropylamine …
Matched Iupac: … 3-phenylpropan-1-amine …
Matched Name: … 3-Phenylpropylamine …
Matched Iupac: … 3-phenylpropan-1-amine …
Nutlin-3
Nutlin-3 is a small molecule inhibitor that targets p53-Mdm2 interaction.
Investigational
Matched Name: … Nutlin-3 …
Matched Description: … Nutlin-3 is a small molecule inhibitor that targets p53-Mdm2 interaction.[A253057] …
Matched Description: … Nutlin-3 is a small molecule inhibitor that targets p53-Mdm2 interaction.[A253057] …
3'-deoxy-3'-aminothymidine monophosphate
Experimental
Matched Name: … 3'-deoxy-3'-aminothymidine monophosphate …
Matched Iupac: … acid ... {[(2S,3S,5R)-3-amino-5-(4-hydroxy-5-methyl-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic …
Matched Iupac: … acid ... {[(2S,3S,5R)-3-amino-5-(4-hydroxy-5-methyl-2-oxo-1,2-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic …
3-(INDOL-3-YL) LACTATE
Experimental
Matched Name: … 3-(INDOL-3-YL) LACTATE …
Matched Iupac: … (2S)-2-hydroxy-3-(1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2S)-2-hydroxy-3-(1H-indol-3-yl)propanoic acid …
Bepranemab
Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human tau protein) (human-rattus norvegicus monoclonal ucb0107 …
Tilavonemab
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human tau protein) (human-mus musculus monoclonal pr-1649264 .gamma.4-chain) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
EDIT-101
EDIT-101 is a recombinant adeno-associated virus pseudotyped with serotype 5 viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein 9) gene editing constructs.
Investigational
Matched Synonyms: … viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein …
Matched Description: … viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein …
Matched Description: … viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein …
R-2-{[4'-Methoxy-(1,1'-Biphenyl)-4-Yl]-Sulfonyl}-Amino-6-Methoxy-Hex-4-Ynoic Acid
Experimental
Matched Name: … R-2-{[4'-Methoxy-(1,1'-Biphenyl)-4-Yl]-Sulfonyl}-Amino-6-Methoxy-Hex-4-Ynoic Acid …
Matched Iupac: … (2R)-6-methoxy-2-{4'-methoxy-[1,1'-biphenyl]-4-sulfonamido}hex-4-ynoic acid …
Matched Iupac: … (2R)-6-methoxy-2-{4'-methoxy-[1,1'-biphenyl]-4-sulfonamido}hex-4-ynoic acid …
(2S,4S,5R)-2-ISOBUTYL-5-(2-THIENYL)-1-[4-(TRIFLUOROMETHYL)BENZOYL]PYRROLIDINE-2,4-DICARBOXYLIC ACID
Experimental
Matched Name: … (2S,4S,5R)-2-ISOBUTYL-5-(2-THIENYL)-1-[4-(TRIFLUOROMETHYL)BENZOYL]PYRROLIDINE-2,4-DICARBOXYLIC ACID …
Matched Iupac: … 5R)-2-(2-methylpropyl)-5-(thiophen-2-yl)-1-[4-(trifluoromethyl)benzoyl]pyrrolidine-2,4-dicarboxylic acid …
Matched Iupac: … 5R)-2-(2-methylpropyl)-5-(thiophen-2-yl)-1-[4-(trifluoromethyl)benzoyl]pyrrolidine-2,4-dicarboxylic acid …
4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid
Experimental
Matched Name: … 4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid …
Matched Iupac: … 3-({4-bromo-2-[(3R,5S)-3,5-dimethylpiperidine-1-carbonyl]phenyl}carbamoyl)propanoic acid …
Matched Iupac: … 3-({4-bromo-2-[(3R,5S)-3,5-dimethylpiperidine-1-carbonyl]phenyl}carbamoyl)propanoic acid …
D-glyceraldehyde 3-phosphate
An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
Experimental
Matched Synonyms: … Glyceraldehyde-3-phosphate ... D-Glyceraldehyde 3-phosphate ... (2R)-2-Hydroxy-3-(phosphonooxy)-propanal …
Matched Name: … D-glyceraldehyde 3-phosphate …
Matched Iupac: … [(2R)-2-hydroxy-3-oxopropoxy]phosphonic acid …
Matched Description: … An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis. …
Matched Name: … D-glyceraldehyde 3-phosphate …
Matched Iupac: … [(2R)-2-hydroxy-3-oxopropoxy]phosphonic acid …
Matched Description: … An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis. …
Estradiol sulfamate
Investigational
Matched Synonyms: … Estradiol 3-sulfamate ... Estradiol-3-O-Sulfamate …
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Oxadiazole
Experimental
Matched Name: … 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Oxadiazole …
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(5-methyl-1,3,4-oxadiazol-2-yl)oxane-3,4,5-triol …
Matched Iupac: … (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(5-methyl-1,3,4-oxadiazol-2-yl)oxane-3,4,5-triol …
9-(6-deoxy-beta-D-allofuranosyl)-6-methylpurine
Experimental
Matched Name: … 9-(6-deoxy-beta-D-allofuranosyl)-6-methylpurine …
Matched Iupac: … (2R,3S,4R,5R)-2-[(1R)-1-hydroxyethyl]-5-(6-methyl-9H-purin-9-yl)oxolane-3,4-diol …
Matched Iupac: … (2R,3S,4R,5R)-2-[(1R)-1-hydroxyethyl]-5-(6-methyl-9H-purin-9-yl)oxolane-3,4-diol …
Displaying drugs 3751 - 3775 of 5775 in total