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Displaying drugs 3901 - 3925 of 4257 in total
Experimental
Matched Name: … 2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID
Matched Iupac: … {[5-(pyridin-2-ylsulfanyl)-1,3-thiazol-2-yl]carbamoyl}amino)methyl]-1H-imidazol-4-yl}phenoxy)acetic acid
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain …
Matched Description: … Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human folate receptor .alpha.) …
Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence. It is unique amongst overactive bladder treatment options in that, unlike other treatments such as solifenacin and darifenacin, it lacks significant antimuscarinic activity, which is...
Approved
Matched Description: … the bladder in the treatment of urinary frequency and incontinence. ... amongst overactive bladder treatment options in that, unlike other treatments such as [solifenacin] and ... antimuscarinic activity,[A232553] which is responsible both for the therapeutic effects of these medications and
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence ... Adrenergic beta-Agonists ... Adrenergic beta-3 Receptor Agonists ... Selective Beta 3-adrenergic Agonists …
Matched Products: … BETMIGA 25 MG UZATILMIŞ SALIMLI FILM TABLET , TABLET, 20 ADET ... BETMIGA 50 MG UZATILMIŞ SALIMLI FILM TABLET ,TABLET, 20 ADET …
Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain.
Investigational
Matched Description: … Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain. …
Matched Categories: … Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … TIAPRID-NEURAX 200 MG ... TIADAL 100 MG TABLET, 20 ADET …
Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor .
Approved
Investigational
Matched Iupac: … [(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
Matched Description: … Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and ... Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat …
Matched Mixtures name: … CIBADREX 20MG/25MG ... CIBADREX 20MG/25MG ... BENAZEPLUS AL 20MG/25MG …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... benazepril and amlodipine ... benazepril and diuretics …
Matched Products: … CIBACEN 20 ... Lotensin 20mg ... BENAZEPRIL 1A PHARMA 20MG
Experimental
Matched Name: … 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine …
Matched Iupac: … 9-butyl-8-[(2,5-dimethoxyphenyl)methyl]-9H-purin-6-amine …
Experimental
Matched Name: … 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine …
Matched Iupac: … 8-[(2,5-dimethoxyphenyl)methyl]-2-fluoro-7H-purin-6-amine …
Experimental
Matched Name: … 1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine …
Matched Iupac: … N-(4-{[3-butyl-2,6-dioxo-1-(prop-2-en-1-yl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}phenyl)acetamide …
Experimental
Matched Name: … N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Matched Iupac: … N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner...
Approved
Investigational
Matched Description: … in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and ... vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and
Matched Mixtures name: … Arlevert 20 mg/40 mg Tabletten …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … ULGERON FORT TABLET, 20 ADET ... SEFAL FORT 75 MG TABLET, 20 ADET …
Experimental
Matched Name: … )-Alpha-D-Erythro-Hexopyranose ... 4-O-(4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Beta-D-Lyxo-Hexopyranosyl …
Experimental
Matched Synonyms: … 1α,2α-epoxy-4βH-p-menth-8-ene …
Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important role in tumor cell growth and survival. Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and...
Approved
Investigational
Matched Description: … plays an important role in tumor cell growth and survival. ... receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and ... L49821] Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … VITRAKVI ORAL SOLUTION 20MG/ML ... VITRAKVI 20 MG/ML ORAL ÇÖZELTİ, 2x50 ML …
Experimental
Matched Name: … [[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
Investigational
Matched Synonyms: … 11-Dehydroprostaglandin F2-alpha
Matched Iupac: … (5Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3-oxocyclopentyl]hept-5-enoic acid
Matched Description: … The principal cyclooxygenase metabolite of arachidonic acid. ... It is released upon activation of mast cells and is also synthesized by alveolar macrophages. ... biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Experimental
Matched Name: … Methyl 4,6-O-[(1R)-1-carboxyethylidene]-beta-D-galactopyranoside …
Matched Iupac: … acid ... (2R,4aR,6R,7R,8R,8aR)-7,8-dihydroxy-6-methoxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxine-2-carboxylic …
Experimental
Matched Name: … 2,4-Dinitrophenyl 2-Deoxy-2-Fluoro-Beta-D-Allopyranoside …
Experimental
Matched Name: … 2,4-DINITROPHENYL 2-DEOXY-2-FLUORO-BETA-D-MANNOPYRANOSIDE …
Ziritaxestat is under investigation in clinical trial NCT03798366 (A Clinical Study to Test How Effective and Safe GLPG1690 is for Patients With Systemic Sclerosis).
Investigational
Matched Synonyms: … 2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)-piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin …
Matched Iupac: … 2-[(2-ethyl-6-{4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl}-8-methylimidazo[1,2-a]pyridin …
Matched Description: … Ziritaxestat is under investigation in clinical trial NCT03798366 (A Clinical Study to Test How Effective and
Investigational
Matched Synonyms: … Benzamide, N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-[2-[8- ... N-(3-(2-cyanopropan-2-yl)-5-(4-methyl-1H-imidazol-1-yl)phenyl)-2-fluoro-4-methyl-5-((8-((1-methyl-1H-pyrazol …
Matched Iupac: … N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-(2-{8-[(1-methyl …
Experimental
Matched Synonyms: … 1-beta-D-Ribofuranosylcytosine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Pinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
Investigational
Matched Synonyms: … DEOXY-5-((CIS-3-(2-(6-(1,1-DIMETHYLETHYL)-1H-BENZIMIDAZOL-2-YL)ETHYL)CYCLOBUTYL)(1-METHYLETHYL)AMINO)-.BETA
Matched Description: … studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and
Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. Roxadustat was first approved...
Approved
Investigational
Matched Iupac: … 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)formamido]acetic acid
Matched Description: … [A245393] Roxadustat was first approved by the European Commission in August 2021.[L40323] ... the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids
Matched Products: … EVRENZO 20 MG FİLM KAPLI TABLET, 12 ADET …
Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor (EGF). EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible...
Approved
Matched Description: … [A227963] Approved by the FDA in February 2004 under the brand name ERBITUX, cetuximab is used for ... /mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and ... the treatment of head and neck cancer and metastatic, KRAS wild-type colorectal cancer, and metastatic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ERBITUX 100 MG/20 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Displaying drugs 3901 - 3925 of 4257 in total