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Displaying drugs 376 - 400 of 1102 in total
Investigational
Matched Synonyms: … Recombinant human arylsulfatase A ... Recombinant human arylsulphatase A …
Matched Name: … Recombinant human arylsulfatase A …
Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Description: … Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient ... It manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing ... effect and modulation of the microbial composition of the dental biofilm [A19581]. …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Sensodyne Sensitivity and Gum Clean and Fresh ... Gum and Enamel Repair ... Gel-Kam Fruit and Berry …
Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Description: … anti-coagulant factor, antithrombin III (ATIII). ... Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold. ... Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and
Matched Salts name: … Fondaparinux sodium
Matched Categories: … Blood and Blood Forming Organs ... Factor Xa Inhibitors ... Indirect factor Xa inhibitors …
Matched Products: … Fondaparinux Sodium ... FONDAPARINUX SODIUM ... Fondaparinux Sodium Injection …
Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine ... Smart Sense allergy and congestion relief indoor and outdoor allergies …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Humana Pharmacy Allergy Relief ... Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief …
Binetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among others.
Investigational
Matched Synonyms: … Interleukin 4 human ... Interleukin 4 (human) ... Interleukin-4 (human; nonglycosylated) …
Matched Description: … treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and
Matched Categories: … Biological Factors ... Immunologic Factors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed...
Approved
Vet approved
Matched Description: … [T457] The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956 …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Salts name: … Liothyronine sodium
Matched Categories: … liothyronine sodium ... Sex Hormones and Insulins ... combinations of levothyroxine and liothyronine ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Liothyronine Sodium ... Liothyronine sodium
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Salts name: … Ceftriaxone sodium
Matched Products: … Ceftriaxone and Dextrose ... Ceftriaxone Sodium ... CEFTRIAXONE SODIUM
Batroxobin is a defibrinogenating hemostatic agent derived from the venom of a pit viper, Bothrops atrox moojeni. In addition to batroxobin, the venom of Bothrops atrox has a composition of 10.2% neutral carbohydrate. Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen. The...
Experimental
Matched Synonyms: … Bothrops atrox blood-coagulation factor X activator …
Matched Description: … The MW of batroxobin is approximately 43,000 g/mol-1, and it contains 231 amino acids. ... Recombinant Batroxobin in relatively affordable and could be accessed by mass production. ... Batroxobin will also bind fibrinogen in a manner different than thrombin and with a higher affinity. …
Matched Categories: … Biological Factors ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Salts name: … Meropenem sodium
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP …
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Description: … Due to a number of factors - for example, the relatively low number of patients per trial and the speed ... for COVID-19 in humans becomes available, the use of ivermectin for these purposes should be avoided ... [L31453] Ivermectin is mainly used in humans in the treatment of onchocerciasis, but may also be effective …
Matched Categories: … Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Neck Hump Removal Patch ... IVOMEC Injection 1% w/v for Cattle and Sheep …
Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Approved
Matched Description: … , concentration, C2/C6 ratio and Maximum Daily Dose. ... HES is a general term and can be sub-classified according to average molecular weight, molar substitution …
Matched Mixtures name: … Hydroxyethyl Starch in Sodium Chloride ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETLİ ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETSİZ …
Matched Categories: … Blood and Related Products ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Matched Products: … Hetastarch in Sodium Chloride ... 6% Hetastarch In 0.9% Sodium Chloride …
Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Synonyms: … Botulism immune globulin IV human ... Botulism immune globulin intravenous (human) ... Human-derived botulism antitoxin antibodies …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... 2003[L39814] and has since been used to treat more than 2100 cases of infant botulism. …
Matched Categories: … Human Immunoglobulin G …
Investigational
Matched Synonyms: … recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and ... a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase …
Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Description: … It was the first statin administered as the active form and not as a prodrug. ... Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Matched Salts name: … Pravastatin sodium
Matched Categories: … pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin and acetylsalicylic acid ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … Pravastatin Sodium ... Pravastatin sodium ... PRAVASTATIN SODIUM
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Synonyms: … HUMAN INTERFERON BETA ... Interferon beta (human) …
Matched Name: … Human interferon beta …
Matched Description: … Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis ... (MS), and was initially approved by the FDA in 1992. ... [L12081] Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and
Matched Categories: … Biological Factors ... Immunologic Factors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Investigational
Matched Synonyms: … Recombinant human galactocerebrosidase …
Matched Name: … Recombinant human galactocerebrosidase …
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Microplasmin (synthetic human) ... Recombinant human microplasmin …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties . It serves as a negative feedback mechanism in the coagulation cascade.
Approved
Matched Synonyms: … Protein S (human) …
Matched Name: … Protein S human
Matched Description: … Protein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties [A19561 …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biological Factors ... Blood Coagulation Factors ... Blood Coagulation Factor Inhibitors …
Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016. It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated. More commonly, fish oil refers to the omega-3-fatty...
Approved
Nutraceutical
Matched Description: … dietary or pharmaceutical intake of these acids is primarily the only way to increase their levels in the human ... It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition ... More commonly, fish oil refers to the omega-3-fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic …
Matched Mixtures name: … Cleanse Gut And Colon …
Matched Products: … Natural Factors Omega 3 Softgels …
VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Description: … It attains high serum levels and is excreted quickly via the urine. …
Matched Salts name: … Cefazolin sodium
Matched Products: … Cefazolin Sodium ... CEFAZOLIN SODIUM ... CEFAZOLINA SODICO 1 G …
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(human tumor necrosis factor receptor superfamily member 4 (act35 antigen ... Immunoglobulin g1-kappa, anti-(homo sapiens tnfrsf4(tumor necrosis factor receptor (tnfr) superfamily …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Investigational
Matched Synonyms: … Recombinant human IL-21 ... L-METHIONYL(HUMAN INTERLEUKIN-21) ... RECOMBINANT HUMAN INTERLEUKIN 21 …
Experimental
Matched Synonyms: … Vitamin B 12 factor IIIm …
Matched Name: … Vitamin B 12 factor IIIm …
Displaying drugs 376 - 400 of 1102 in total