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Displaying drugs 376 - 400 of 724 in total
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and...
Approved
Matched Synonyms: … 40-O-(2-hydroxyethyl)-rapamycin ... 42-O-(2-Hydroxyethyl)rapamycin …
Matched Description: … Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian ... In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and ... not on the mTORC2 protein. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Mammalian target of rapamycin (mTOR) kinase inhibitors …
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Synonyms: … Oxybenzene
Matched Description: … It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly ... Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. …
Matched Mixtures name: … Poison Oak and Ivy ... OFF Bite and Itch Relief First Aid Antiseptic ... Major Camphor and Phenol …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives ... Compounds used in a research, industrial, or household setting …
Matched Products: … Care One Sore Throat …
Experimental
Matched Synonyms: … 6-Deoxy-2-O-methyl-β-L-galactopyranose ... 6-Deoxy-2-O-methyl-beta-L-galactopyranose …
Matched Name: … 2-O-Methyl-beta-L-fucopyranose …
Experimental
Matched Synonyms: … 6-deoxy-2-O-methyl-α-L-galactopyranose ... 6-deoxy-2-O-methyl-alpha-L-galactopyranose …
Matched Name: … 2-O-methyl-alpha-L-fucopyranose …
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Synonyms: … o-guaiacol ... o-Methoxyphenol ... o-hydroxyanisole …
Matched Description: … Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. ... Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. …
Experimental
Matched Synonyms: … o-Cymen-5-ol ... o-Cymen-5y-ol
Matched Name: … o-Cymen-5-ol
Experimental
Matched Name: … Salicylamide O-acetic acid …
Investigational
Matched Name: … 2-O-desulfated heparin …
Experimental
Matched Name: … O-Benzylsulfonyl-Serine …
Experimental
Matched Synonyms: … alpha-D-Glucopyranoside, 6-O-(1-oxooctyl)-beta-D-fructofuranosyl …
Matched Name: … 6-o-Capryloylsucrose …
Matched Iupac: … 5S)-3,4-dihydroxy-5-(hydroxymethyl)-5-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy
Experimental
Matched Name: … Tyramine O-sulfate …
INO-4995 is an inositol tetrakisphosphate analog being investigated for Cystic Fibrosis.
Investigational
Matched Synonyms: … 2-O-butyryl-1-O-octyl-myo-Inositol 3,4,5,6-tetrakisphosphate octakis(propionoxymethyl)ester …
Matched Iupac: … (1S,2S,3R,4R,5S,6R)-2,3,4,5-tetrakis({bis[(propanoyloxy)methoxy]phosphoryl}oxy)-6-(octyloxy)cyclohexyl …
Experimental
Matched Synonyms: … 4,5-Dimethyl-o-phenylenediamine …
Investigational
Matched Synonyms: … 6-O-Butanoylcastanospermine …
Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Description: … and also a drug of abuse. ... Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant …
Matched Mixtures name: … Cold and Flu All In One ... Cold and Flu-IN-one Extra Strength ... Mucus Relief All In One Cold and Flu …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... bupropion and dextromethorphan ... Heterocyclic Compounds with 4 or More Rings ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake …
Matched Products: … Up and Up Cough Suppressant DM ... Up and Up 12 Hour Cough Relief ... Foster and Thrive 12 Hour Cough Relief …
Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … 7-o-methyl-.gamma.-mangostin ... 7-o-methyl-4-desprenylcostatin …
Matched Description: … Mangostin is a plant/plant extract used in some OTC (over-the-counter) products. …
Investigational
Matched Synonyms: … O-aminophthalylhydrazide ... O-aminophthaloyl hydrazide …
Matched Categories: … Indicators and Reagents ... Compounds used in a research, industrial, or household setting …
Experimental
Matched Synonyms: … 6-O-phosphono-L-gulonic acid …
Experimental
Matched Synonyms: … 4-O-phosphono-L-threonic acid …
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Iupac: … [15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one ... 24'S)-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy ... -2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one; (1'R,2R,4'S,5S ... }-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-6-(propan-2-yl)-3',7',19'-trioxaspiro[oxane ... 2-yl]-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... with statistical errors and accusations of plagiarism. ... _in vitro_ data, and the clinical utility of this data remains unclear. …
Matched Categories: … Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents ... Compounds used in a research, industrial, or household setting …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... I-Dectin 0.5 % Pour-On ... Vimectin 0.5% w/v Pour On
A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Approved
Matched Synonyms: … N,N-dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]ethylamine ... o-methyldiphenhydramine ... o-monomethyldiphenhydramine …
Matched Description: … A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm …
Matched Mixtures name: … MYOGESIC-O ... MYOGESIC-OR ... Orphenadrine Citrate, Aspirin and Caffeine …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Experimental
Matched Synonyms: … O-(N-Acetyl-alpha-neuraminosyl)-(2->3)-o-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose …
Matched Iupac: … }oxan-4-yl]oxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid ... 6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Description: … conditions of the premature newborn, pain relief, and to combat drowsiness. ... development and may eventually cause asthma or early onset emphysema in those born prematurely. ... [T716] Caffeine is also used in a variety of cosmetic products and can be administered topically, orally …
Matched Mixtures name: … EMOL OSK ... Midol One ... OKA GALEZ …
Matched Categories: … combinations of xanthines ... caffeine and sodium benzoate ... Caffeine and Caffeine Containing Products ... Respiratory and CNS Stimulants ... Anorexigenic Agents & Respiratory and CNS Stimulants …
Matched Products: … Caffeine and Sodium Benzoate …
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2 ... (2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R ... Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene …
Matched Description: … [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament ... [A259023] However, it could potentially be due to the short timeframe of tofersen treatment, and more ... [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … 3-O-Methylglucose ... O(3)-methyl-D-glucose …
Matched Name: … 3-O-Methyl-d-glucose …
Displaying drugs 376 - 400 of 724 in total