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Displaying drugs 4076 - 4100 of 9434 in total
Indoleacetamide
Experimental
Matched Synonyms: … 3-indoleacetamide ... Indole-3-acetamide ... 1H-indole-3-acetamide …
Matched Iupac: … 2-(1H-indol-3-yl)acetamide …
Matched Iupac: … 2-(1H-indol-3-yl)acetamide …
NS-3728
NS3728 is an orally active chloride channel blocker for the treatment of cancer.
Investigational
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
(S)-Warfarin
Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.
Experimental
Investigational
Matched Synonyms: … (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone ... 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one …
Matched Iupac: … 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one …
Matched Iupac: … 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one …
24-Homo-1,25-dihydroxyvitamin D3
24-Homo-1,25-dihydroxyvitamin D3 is a novel vitamin D analogue.
Experimental
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-7-hydroxy-7-methyloctan-2-yl]-7a-methyl-octahydro-1H-inden-4 ... -ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol …
ICG-136
ICG-136 is a compound chimeric antigen receptor (cCAR) T-cell therapy developed by iCell Gene Therapeutics. It was investigated for the treatment of acute myeloid leukemia.
Investigational
X-165
Investigational
Matched Synonyms: … (R)-N-(1-(1-(1H-indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4,5]decan-8-yl)-3-methyl-1-oxobutan …
AZD-0424
AZD0424 has been used in trials studying the treatment of Advanced Solid Tumours.
Investigational
Matched Iupac: … 1-[4-(2-{[4-({6-chloro-2H-[1,3]dioxolo[4,5-b]pyridin-7-yl}amino)-5-(propan-2-yloxy)quinazolin-7-yl]oxy ... }ethyl)piperazin-1-yl]ethan-1-one …
(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine
Experimental
Matched Name: … (2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl ... -1-fluorobutan-2-amine …
Matched Iupac: … (2S,3S)-3-[3-(2-chloro-4-methanesulfonylphenyl)-1,2,4-oxadiazol-5-yl]-1-cyclopentylidene-4-cyclopropyl ... -1-fluorobutan-2-amine …
Matched Iupac: … (2S,3S)-3-[3-(2-chloro-4-methanesulfonylphenyl)-1,2,4-oxadiazol-5-yl]-1-cyclopentylidene-4-cyclopropyl ... -1-fluorobutan-2-amine …
Pseudosaccharin chloride
Experimental
Matched Synonyms: … 3-Chloro-psi-saccharin ... 3-Chlorobenzo(d)isothiazole 1,1-dioxide …
Matched Iupac: … 3-chloro-1lambda6,2-benzothiazole-1,1-dione …
Matched Iupac: … 3-chloro-1lambda6,2-benzothiazole-1,1-dione …
Alrizomadlin
Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … Bicyclo(2.2.2)octane-1-carboxylic acid, 4-((((3'r,4's,5'r)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1' ... -3',3''-indoline]-5'-carboxamido)bicyclo [2.2.2]octane-1-carboxylic acid ... 4-((3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine …
Matched Iupac: … 4-{[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane ... -1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid …
Matched Iupac: … 4-{[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane ... -1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid …
3-(4-NITRO-PHENOXY)-PROPAN-1-OL
Experimental
Matched Name: … 3-(4-NITRO-PHENOXY)-PROPAN-1-OL …
Matched Iupac: … 3-(4-nitrophenoxy)propan-1-ol …
Matched Iupac: … 3-(4-nitrophenoxy)propan-1-ol …
JQ1
First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Iupac: … tert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6 …
Benzoylecgonine
Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for...
Experimental
Illicit
Matched Synonyms: … 3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid ... (1R,2R,3S,5S)-8-methyl-3-[(phenylcarbonyl)oxy]-8-azabicyclo[3.2.1]octane-2-carboxylic acid …
Matched Iupac: … (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid …
Matched Iupac: … (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid …
4-(1,3,2-Dioxaborolan-2-Yloxy)Butan-1-Aminium
Experimental
Matched Name: … 4-(1,3,2-Dioxaborolan-2-Yloxy)Butan-1-Aminium …
Matched Iupac: … 4-(1,3,2-dioxaborolan-2-yloxy)butan-1-aminium …
Matched Iupac: … 4-(1,3,2-dioxaborolan-2-yloxy)butan-1-aminium …
OCU-100
Investigational
Matched Synonyms: … LEDGF(1-326) ... Lens epithelial derived growth factor (1-326) …
Tuparstobart
Tuparstobart is under investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS ≥ 1) Recurrent/metastatic Squamous Cell Carcinoma of the Head and Neck).
Investigational
Matched Synonyms: … (218) (122-219), hinge 1-15 (220-234), CH2 N8 ... Anti-LAG-3 Monoclonal Antibody INCAGN02385 ... immunoglobulin G1-kappa,anti-[Homo sapiens LAG3 (lymphocyte activating 3, lymphocyte-activation 3, CD223 …
Matched Description: … With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS ≥ 1) …
Matched Description: … With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS ≥ 1) …
AT9283
AT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.
Investigational
Matched Synonyms: … 1-Cyclopropyl-3-[3-(5-morpholin-4-ylmethyl-1H-benzoimidazol-2-yl)-1H-pyrazol-4-yl]-urea …
Matched Iupac: … N'-cyclopropyl-N-(3-{5-[(morpholin-4-yl)methyl]-1H-1,3-benzodiazol-2-yl}-1H-pyrazol-4-yl)carbamimidic …
Matched Iupac: … N'-cyclopropyl-N-(3-{5-[(morpholin-4-yl)methyl]-1H-1,3-benzodiazol-2-yl}-1H-pyrazol-4-yl)carbamimidic …
N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide
Experimental
Matched Name: … N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide …
Matched Iupac: … N-(3-cyclopropyl-1H-pyrazol-5-yl)benzamide …
Matched Iupac: … N-(3-cyclopropyl-1H-pyrazol-5-yl)benzamide …
MUC1 Dendritic Cell Vaccine
Dendritic Cell (DC) Therapy is a newly emerging and potent form of immune therapy that amplifies the actions of the body's own immune system to help fight cancer, AIDS and other serious conditions. The Dendritic Cell is an immune cell whose role is the recognition, processing and presentation of foreign...
Investigational
Arabinouridine 3'-phosphate
Experimental
Matched Synonyms: … 1-(3-O-phosphono-beta-L-arabinofuranosyl)Pyrimidine-2,4(1H,3H)-Dione ... Arabinouridine 3'-Phosphate ... Uracil arabinose-3'-phosphate …
Matched Name: … Arabinouridine 3'-phosphate …
Matched Iupac: … {[(2R,3S,4S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl …
Matched Name: … Arabinouridine 3'-phosphate …
Matched Iupac: … {[(2R,3S,4S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl …
PLX-4720
Experimental
Matched Synonyms: … N-[3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide …
Matched Iupac: … N-(3-{5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide …
Matched Iupac: … N-(3-{5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide …
Luminol
Investigational
Matched Synonyms: … 3-aminophthalic hydrazide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Parathyroid Hormone-Related Protein 1-36
Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and PTH to Treat Osteoporosis).
Investigational
Matched Synonyms: … 1-36 hpthrp ... 1-36 human humoral hypercalcemic factor ... Parathyroid hormone-related protein 1-36 …
Matched Name: … Parathyroid Hormone-Related Protein 1-36 …
Matched Description: … Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison …
Matched Name: … Parathyroid Hormone-Related Protein 1-36 …
Matched Description: … Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison …
2-[3-chloro-6-[2,2-difluoro-2-(1-oxidopyridin-1-ium-2-yl)ethyl]imino-1-hydroxypyridin-2-yl]-N-[(1R)-1-(3-chlorophenyl)ethyl]acetamide
Experimental
Matched Name: … 2-[3-chloro-6-[2,2-difluoro-2-(1-oxidopyridin-1-ium-2-yl)ethyl]imino-1-hydroxypyridin-2-yl]-N-[(1R)-1 ... -(3-chlorophenyl)ethyl]acetamide …
Matched Iupac: … 2-(2-{[(2E)-5-chloro-6-({[(1R)-1-(3-chlorophenyl)ethyl]carbamoyl}methyl)-1-hydroxy-1,2-dihydropyridin ... -2-ylidene]amino}-1,1-difluoroethyl)pyridin-1-ium-1-olate …
Matched Iupac: … 2-(2-{[(2E)-5-chloro-6-({[(1R)-1-(3-chlorophenyl)ethyl]carbamoyl}methyl)-1-hydroxy-1,2-dihydropyridin ... -2-ylidene]amino}-1,1-difluoroethyl)pyridin-1-ium-1-olate …
AT-001
AT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).
Investigational
Matched Iupac: … 2-(8-oxo-7-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-7H,8H-pyrazino[2,3-d]pyridazin-5-yl)acetic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 4076 - 4100 of 9434 in total