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Displaying drugs 4126 - 4150 of 10056 in total

Epaminurad

Epaminurad is under investigation in clinical trial NCT05815901 (A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patients).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

{[2-(1h-1,2,3-Benzotriazol-1-Yl)-2-(3,4-Difluorophenyl)Propane-1,3-Diyl]Bis[4,1-Phenylene(Difluoromethylene)]}Bis(Phosphonic Acid)

Experimental
Matched Name: … {[2-(1h-1,2,3-Benzotriazol-1-Yl)-2-(3,4-Difluorophenyl)Propane-1,3-Diyl]Bis[4,1-Phenylene(Difluoromethylene …
Matched Iupac: … ({4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluoro(phosphono)methyl]phenyl}-2-(3,4-difluorophenyl)propyl …

(2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid

Experimental
Matched Name: … (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid …
Matched Iupac: … (2S)-3-{[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl}-2-benzylpropanoic acid …

(2S)-N-[(3E)-5-Cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxo-1-imidazolidinyl)phenyl]propanamide

Experimental
Matched Name: … (2S)-N-[(3E)-5-Cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxo-1-imidazolidinyl)phenyl]propanamide …
Matched Iupac: … (2S)-N-[(3E)-5-cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxoimidazolidin-1-yl)phenyl]propanamide …

BMS-214662

BMS-214662 has been used in trials studying the treatment of Childhood Myelodysplastic Syndromes, Refractory Anemia With Excess Blasts, Recurrent Adult Acute Myeloid Leukemia, Relapsing Chronic Myelogenous Leukemia, and Adult Acute Promyelocytic Leukemia (M3), among others.
Investigational
Matched Iupac: … (3R)-3-benzyl-1-[(1H-imidazol-5-yl)methyl]-4-(thiophene-2-sulfonyl)-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine ... -7-carbonitrile …
Matched Salts cas: … 474010-58-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

4-(2-(3-Propyl-(1,2,4)oxadiazol-5-yl)-vinyl)-benzene-1,2-diol

Investigational
Matched Name: … 4-(2-(3-Propyl-(1,2,4)oxadiazol-5-yl)-vinyl)-benzene-1,2-diol …
Matched Iupac: … 4-[(1E)-2-(3-propyl-1,2,4-oxadiazol-5-yl)ethenyl]benzene-1,2-diol …

Sarsagenin

Investigational
Matched Synonyms: … (3.beta.,5.beta.,25s)-spirostan-3-ol ... Spirostan-3-ol, (3.beta.,5.beta.,25s)- …
Matched Iupac: … (1'R,2R,2'S,4'S,5S,7'S,8'R,9'S,12'S,13'S,16'S,18'R)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo …

Arabinouridine 3'-phosphate

Experimental
Matched Synonyms: … 1-(3-O-phosphono-beta-L-arabinofuranosyl)Pyrimidine-2,4(1H,3H)-Dione ... Arabinouridine 3'-Phosphate ... Uracil arabinose-3'-phosphate …
Matched Name: … Arabinouridine 3'-phosphate …
Matched Iupac: … {[(2R,3S,4S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl …

Denifanstat

Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor. Due to its antineoplastic activities, it is being investigated for various cancers.
Investigational
Matched Synonyms: … Benzonitrile, 4-(1-(4-cyclobutyl-2-methyl-5-(3-methyl-1h-1,2,4-triazol-5-yl)benzoyl)-4-piperidinyl)- …
Matched Iupac: … 4-{1-[4-cyclobutyl-2-methyl-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzoyl]piperidin-4-yl}benzonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Colforsin

Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.
Experimental
Investigational
Matched Iupac: … (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro …

5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide

Experimental
Matched Name: … 5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene ... -2-carboxamide …
Matched Iupac: … 5-chloro-N-[(3R)-1-({[2-fluoro-4-(2-oxo-1,2-dihydropyridin-1-yl)phenyl]carbamoyl}methyl)pyrrolidin-3- ... yl]thiophene-2-carboxamide …

Temuterkib

Investigational
Matched Synonyms: … 5,6-dihydro-6,6-dimethyl-2-(2-((1-methyl-1h-pyrazol-5-yl)amino)-4-pyrimidinyl)-5-(2-(4-morpholinyl)ethyl ... 4h-thieno(2,3-c)pyrrol-4-one, 5,6-dihydro-6,6-dimethyl-2-(2-((1-methyl-1h-pyrazol-5-yl)amino)-4-pyrimidinyl ... )-5-(2-(4-morpholinyl)ethyl)- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol

Experimental
Matched Name: … 2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol …
Matched Iupac: … 2-(1H-pyrrole-1-carbonyl)benzene-1,3,5-triol …

Chelerythrine

A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.
Investigational
Matched Iupac: … 17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{14,19}]henicosa-1(13) …
Matched Categories: … Heterocyclic Compounds, 3-Ring …

N-(4-OXO-5,6,7,8-TETRAHYDRO-4H-[1,3]THIAZOLO[5,4-C]AZEPIN-2-YL)ACETAMIDE

Experimental
Matched Name: … N-(4-OXO-5,6,7,8-TETRAHYDRO-4H-[1,3]THIAZOLO[5,4-C]AZEPIN-2-YL)ACETAMIDE …
Matched Iupac: … N-{4-oxo-4H,5H,6H,7H,8H-[1,3]thiazolo[5,4-c]azepin-2-yl}acetamide …

beta-Naphthoflavone

β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.
Experimental
Matched Synonyms: … 3-phenyl-1H-naphtho(2,1-b)pyran-1-one …
Matched Iupac: … 3-phenyl-1H-benzo[f]chromen-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

Boldenone

Boldenone is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It is not indicated for use in humans in the US and is only available through veterinary clinics.
Illicit
Vet approved
Matched Synonyms: … 1,4-Androstadien-17β-ol-3-one ... 1,4-Androstadien-17beta-ol-3-one ... 17β-hydroxyandrosta-1,4-dien-3-one …
Matched Iupac: … [a]phenanthren-7-one ... (1S,3aS,3bR,9aR,9bS,11aS)-1-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta …

(2S)-2-Ammonio-3-[5-(2-methyl-2-propanyl)-3-oxido-1,2-oxazol-4-yl]propanoate

Experimental
Matched Name: … (2S)-2-Ammonio-3-[5-(2-methyl-2-propanyl)-3-oxido-1,2-oxazol-4-yl]propanoate …
Matched Iupac: … 4-[(2S)-2-amino-2-carboxyethyl]-5-tert-butyl-1,2-oxazol-3-olate …

Cardiopet

Cardiopet is under investigation in clinical trial NCT01826773 (Cardiopet as PET Imaging Agent to Assess Myocardial Perfusion and Fatty Acid Uptake in Known or Suspected CAD Subjects).
Investigational
Matched Synonyms: … 2-((1s,2r)-2-(5-(fluoro-18f)tridecyl)cyclopropyl)acetic acid ... Cyclopropaneacetic acid, 2-(5-(fluoro-18f)tridecyl)-, (1r,2s)-rel- …

6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine

Experimental
Matched Name: … 6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine …
Matched Iupac: … 6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(propan-2-yl)-1,3-benzothiazol-2-amine …

(S)-2-((S)-3-isobutyl-2,5-dioxo-4-quinolin-3-ylmethyl-[1,4]diazepan-1yl)-N-methyl-3-naphtalen-2-yl-propionamide

Experimental
Matched Name: … (S)-2-((S)-3-isobutyl-2,5-dioxo-4-quinolin-3-ylmethyl-[1,4]diazepan-1yl)-N-methyl-3-naphtalen-2-yl-propionamide …
Matched Iupac: … (2S)-N-methyl-2-[(3S)-3-(2-methylpropyl)-2,5-dioxo-4-[(quinolin-3-yl)methyl]-1,4-diazepan-1-yl]-3-(naphthalen ... -2-yl)propanamide …

2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE-1-CARBOXYLIC ACID

Experimental
Matched Name: … 2-[({2-[(1Z)-3-(DIMETHYLAMINO)PROP-1-ENYL]-4-FLUOROPHENYL}SULFONYL)AMINO]-5,6,7,8-TETRAHYDRONAPHTHALENE ... -1-CARBOXYLIC ACID …
Matched Iupac: … 2-{2-[(1Z)-3-(dimethylamino)prop-1-en-1-yl]-4-fluorobenzenesulfonamido}-5,6,7,8-tetrahydronaphthalene ... -1-carboxylic acid …

4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID

Experimental
Matched Name: … 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID …
Matched Iupac: … 4-{[1-methyl-2,4-dioxo-6-(3-phenylprop-1-yn-1-yl)-1,2,3,4-tetrahydroquinazolin-3-yl]methyl}benzoic acid …

JNJ-28312141

Investigational
Matched Synonyms: … 1h-imidazole-2-carboxamide, 5-cyano-n-(2-(1-cyclohexen-1-yl)-4-(1-(2-(dimethylamino)acetyl)-4-piperidinyl ... 4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide …
Matched Iupac: … 4-cyano-N-[2-(cyclohex-1-en-1-yl)-4-{1-[2-(dimethylamino)acetyl]piperidin-4-yl}phenyl]-1H-imidazole-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Cotsiranib

Investigational
Matched Synonyms: … (TGF-beta 1) and cyclo-oxygenase-2 (COX-2)) ... STP705 (small interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 …
Displaying drugs 4126 - 4150 of 10056 in total