Displaying drugs 4201 - 4225 of 8090 in total
PH94B
PH94B is being developed by Pherin Pharmaceuticals, Inc. for the treatment of social phobias (generalized anxiety disorder). It is a member of a new family of pharmaceutical compounds called vomeropherins.
Investigational
Matched Description: … It is a member of a new family of pharmaceutical compounds called vomeropherins. ... PH94B is being developed by Pherin Pharmaceuticals, Inc. for the treatment of social phobias (generalized …
BTA9881
BTA9881 is a respiratory syncytial virus (RSV) antiviral drug developed by the Australian company Biota Holdings. It is currently in phase I trials.
Investigational
APD791
APD791 is an oral anti-thrombotic drug candidate being evaluated in a Phase 1 clinical trial by Arena. APD791 is intended to lower the risk of arterial thrombosis by reducing the amplification of platelet aggregation, arterial constriction and intimal hyperplasia mediated by serotonin.
Investigational
Matched Description: … APD791 is intended to lower the risk of arterial thrombosis by reducing the amplification of platelet …
Tofisopam
Tofisopam (marketed under brand names Emandaxin and Grandaxin) is a 2,3-benzodiazepine drug which is a benzodiazepine derivative. In contrast to classical 1,4-benzodiazepines, the compound does not bind to the benzodiazepine binding site of the gamma-aminobutyric acid receptor and its psychopharmacological profile differs from such compounds. Although Tofisopam is not approved...
Experimental
Matched Description: … contrast to classical 1,4-benzodiazepines, the compound does not bind to the benzodiazepine binding site of ... approved for sale in North America, it is approved for use in various countries worldwide, including parts of ... The D-enantiomer ([dextofisopam]) is currently in phase II trials in the U.S. for the treatment of irritable …
Captodiame
Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.
Experimental
Matched Description: … It is a derivative of diphenhydramine. …
Vilobelimab
Vilobelimab is a chimeric monoclonal immunoglobulin G4 (IgG4) antibody that binds to the soluble form of human C5a with high affinity. It consists of mouse anti-human complement factor 5a (C5a) monoclonal binding sites (variable regions of heavy and light chain regions) and human gamma 4 heavy chain and light kappa...
Investigational
Matched Description: … Vilobelimab is a chimeric monoclonal immunoglobulin G4 (IgG4) antibody that binds to the soluble form of ... It consists of mouse anti-human complement factor 5a (C5a) monoclonal binding sites (variable regions ... of heavy and light chain regions) and human gamma 4 heavy chain and light kappa chain constant regions …
Medical Cannabis
The use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical conditions as a wave of legalization in North America has changed public and medical opinion on its use. Consequently, an...
Experimental
Investigational
Matched Description: … , a class of compounds that act upon cannabinoid receptors of the body [A32584]. ... gained popularity in recent years for the management of a wide variety of medical conditions as a wave ... of the marijuana plant, both of which interact with the cannabinoid receptors that are found throughout …
Histidine
An essential amino acid that is required for the production of histamine.
Investigational
Nutraceutical
Matched Description: … An essential amino acid that is required for the production of histamine. …
Metharbital
Metharbital is a barbiturate anticonvulsant, similar to phenobarbital, marketed as Gemonil by Abbott Laboratories. It was patented in 1905 by Emil Fischer of Merck.
Withdrawn
Matched Description: … It was patented in 1905 by Emil Fischer of Merck. …
Apramycin
Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria. Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans.
Experimental
Vet approved
Halofuginone
Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S....
Investigational
Vet approved
Matched Description: … Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1 ... Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received …
Picoplatin
Picoplatin is a cytotoxic platinum compound in clinical development for the treatment of patients with solid tumors. It causes apoptosis (cell death) by binding to DNA and interfering with DNA replication and transcription.
Investigational
Matched Description: … Picoplatin is a cytotoxic platinum compound in clinical development for the treatment of patients with …
Becocalcidiol
Becocalcidiol is a vitamin D(3) analogue which has not caused hypercalcaemia or significant irritation in preclinical trials.
Investigational
AM103
AM103 is a novel inhibitor of 5-lipoxygenase-activiting protein (FLAP) that has demonstrated potential to treat asthma and cardiovascular disease by preventing the synthesis of LT, which triggers inflammation. It is being developed by Amira.
Investigational
Matched Description: … AM103 is a novel inhibitor of 5-lipoxygenase-activiting protein (FLAP) that has demonstrated potential ... to treat asthma and cardiovascular disease by preventing the synthesis of LT, which triggers inflammation …
Telapristone acetate
Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
Investigational
Black cohosh
Black cohosh (Actaea racemosa or Cimicifuga racemosa), a member of the buttercup family, is a perennial plant which native to North America. Historical names for this plant include snakeroot, black bugbane, rattleweed, macrotys, and rheumatism weed. Black cohosh has a long history of use. Native Americans used it for its...
Experimental
Matched Description: … Black cohosh has a long history of use. ... [A32543]
The American College of Obstetrics and Gynecology guidelines on the use of botanicals, such ... as black cohosh, for the management of menopausal symptoms the use of for up to six months, especially …
Fludiazepam
Fludiazepam is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a scheduled drug in the U.S., but is approved for use in Japan.
Experimental
Illicit
Merimepodib
Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH. Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog lymphocytes at concentrations of approximately 100 nM.
Investigational
Matched Description: … lymphocytes at concentrations of approximately 100 nM. ... Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH. ... Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog …
Darusentan
Darusentan is a selective endothelin ETA receptor antagonist. It is being evaluated as a treatment for congestive heart failure and hypertension.
Investigational
Pagoclone
Pagoclone is an anxiolytic drug from the cyclopyrrolone family, which is related to other more well known drugs such as the sleeping medication zopiclone. It is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with...
Investigational
Matched Description: … It is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which …
Brilaroxazine
Brilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. Reviva Pharmaceuticals also intends to investigate RP5063 for the treatment of bipolar disorder, major depressive disorder, psychosis/agitation associated with Alzheimer's disease, Parkinson's disease psychosis, attention deficit hyperactivity disorder...
Investigational
Matched Description: … As of May 2015, it is in phase III clinical trials for schizophrenia. ... Reviva Pharmaceuticals also intends to investigate RP5063 for the treatment of bipolar disorder, major ... investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of …
Temocapril
Temocapril is a prodrug-type angiotensin-I converting enzyme (ACE) inhibitor not approved for use in the United States, but is approved in Japan and South Korea. Temocapril can also be used in hemodialysis patients without risk of serious accumulation.
Experimental
Investigational
Matched Description: … Temocapril can also be used in hemodialysis patients without risk of serious accumulation. …
Calanolide A
Calanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found in the Malaysian rain forest. A related compound, calanolide B, also has anti-HIV activity. Both drugs are being developed by Sarawak Pharmaceuticals. A preliminary dosing study among HIV-infected individuals showed a significant antiviral effect compared...
Investigational
Parasorbic acid
Sole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe berries of the mountain ash.
Experimental
Matched Description: … Sole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe ... berries of the mountain ash. …
Displaying drugs 4201 - 4225 of 8090 in total