Displaying drugs 4226 - 4250 of 9253 in total
XEN-2174
XEN-2174 is a synthetic drug modeled on a peptide from the venom of a cone shell found on Australia's Great Barrier Reef. XEN-2174 represents a new class of molecules, called the chi conopeptides that selectively inhibit the Norepinephrine Transporter (NET). NET is the primary mechanism regulating the biological effects of...
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
LY2140023
LY2140023 is an investigational drug from Lilly, which is being developed as a new treatment option for schizophrenia. LY2140023 is an oral "prodrug," meaning it is devoid of intrinsic biological activity and, once administered, is metabolized to provide the active mGlu2/3 receptor agonist called LY404039. Most currently approved antipsychotic medications...
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Friulimicin B
Friulimicin B is a naturally occurring antibiotic produced by a micro-organism, Actinoplanes friuliensis. It shows strong cidal activity against a number of Gram-positive pathogens which commonly cause serious infections in hospital patients and which are becoming more routinely acquired in the community.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Entolimod
Entolimod has been used in trials studying the treatment of Mucositis, Tongue Cancer, Colorectal Cancer, Stage IVA Verrucous Carcinoma of the Larynx, and Stage IVB Verrucous Carcinoma of the Larynx, among others.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Isunakinra
Isunakinra has been investigated for the treatment of Dry Eye and Allergic Conjunctivitis (AC).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Davalintide
Davalintide is under investigation in clinical trial NCT00785408 (Study to Examine Safety, Tolerability and Effect on Body Weight of Subcutaneous AC2307 in Obese or Overweight Subjects).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cotadutide
Cotadutide is under investigation in clinical trial NCT03444584 (Study of MEDI0382 in Combination With Dapagliflozin and Metformin in Overweight/Obese Subject With Type 2 Diabetes).
Investigational
Matched Iupac: … (2S)-4-{[(5S)-5-[(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S,3R)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Survodutide
Survodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mazdutide
Mazdutide is under investigation in clinical trial NCT06143956 (A Chronic Weight Management Master Protocol Study (LY900038) of Multiple Intervention-specific-appendices (Isas) in Adult Participants With Obesity or Overweight).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Semagacestat
Semagacestat has been used in trials studying the treatment of Alzheimer Disease.
Investigational
Matched Categories: … Amino Acids ... Amino Acids, Peptides, and Proteins …
Fosinoprilat
Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
Experimental
Matched Categories: … Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Peptides, and Proteins …
NX-1207
NX-1207 is an investigational new drug for BPH, whose chemical entity and mechanism of action remain undisclosed. Nymox Pharmaceutical Corporation recently completed studies of NX-1207 for treatment of benign prostatic hyperplasia (BPH).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Luvadaxistat
Luvadaxistat is under investigation in clinical trial NCT03214588 (Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia).
Investigational
Matched Categories: … D-Amino Acid Oxidase Inhibitor …
Preimplantation factor
Preimplantation factor is under investigation in clinical trial NCT03593460 (Phase II Autoimmune Hepatitis).
Investigational
Matched Iupac: … (2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-6-amino-2-[ ... (2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-3-methylbutanamido]-5-carbamimidamidopentanamido …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Kynurenic Acid
Kynurenic Acid is under investigation in clinical trial NCT02340325 (FS2 Safety and Tolerability Study in Healthy Volunteers).
Investigational
Matched Categories: … Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
Tris(Hydroxyethyl)Aminomethane
Experimental
Matched Iupac: … 3-amino-3-(2-hydroxyethyl)pentane-1,5-diol …
5'-O-(N-(Alanyl)sulfamoyl)adenosine
Experimental
Matched Iupac: … amino]propan-1-one ... (2S)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl) …
Matched Categories: … Amino Acids ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids ... Amino Acids, Peptides, and Proteins …
Cenisertib
Cenisertib is an aurora kinase inhibitor.
Investigational
Matched Iupac: … (1S,2S,3R,4R)-3-[(5-fluoro-2-{[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]bicyclo …
Aeruginosin 98-B
Experimental
Matched Iupac: … [(2S,3aS,6R,7aS)-2-({4-[(diaminomethylidene)amino]butyl}carbamoyl)-1-[(2R,3R)-2-[(2R)-2-hydroxy-3-(4- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
REV131
rEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Larazotide
An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
SER-100
SER-100 is under investigation in clinical trial NCT01987284 (SER100 in Isolated Systolic Hypertension).
Investigational
Matched Iupac: … (2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)- ... 6-amino-2-[(2S)-2-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2S)-2-[(2S)-5-carbamimidamido-2-acetamidopentanamido …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 4226 - 4250 of 9253 in total