Displaying drugs 4376 - 4400 of 5277 in total
2,6-DIMETHYL-1-(3-[3-METHYL-5-ISOXAZOLYL]-PROPANYL)-4-[4-METHYL-2H-TETRAZOL-2-YL]-PHENOL
Experimental
Matched Name: … 2,6-DIMETHYL-1-(3-[3-METHYL-5-ISOXAZOLYL]-PROPANYL)-4-[4-METHYL-2H-TETRAZOL-2-YL]-PHENOL …
Matched Iupac: … 2-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-methyl-2H-1,2,3,4-tetrazole …
Matched Iupac: … 2-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-methyl-2H-1,2,3,4-tetrazole …
Anisotropine methylbromide
Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary...
Approved
Matched Synonyms: … 8-Methyl-3-(2-propylpentanoyloxy)tropinium bromide ... endo-8,8-Dimethyl-3-((1-oxo-2-propylpentyl)oxy)-8-azoniabicyclo(3.2.1)octane bromide …
Matched Iupac: … 8,8-dimethyl-3-[(2-propylpentanoyl)oxy]-8-azabicyclo[3.2.1]octan-8-ium bromide …
Matched Description: … gastric acid secretion. ... gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. …
Matched Iupac: … 8,8-dimethyl-3-[(2-propylpentanoyl)oxy]-8-azabicyclo[3.2.1]octan-8-ium bromide …
Matched Description: … gastric acid secretion. ... gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. …
Fimepinostat
Fimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.
Investigational
Matched Synonyms: … 5-pyrimidinecarboxamide, N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin ... N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and …
Matched Salts cas: … 1401998-36-4 …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and …
Matched Salts cas: … 1401998-36-4 …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Ceftaroline fosamil
Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria:
Acute bacterial skin and skin structure infections.
Community-acquired bacterial pneumonia.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin …
Matched Iupac: … ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]sulfanyl}-1,3-thiazol-4-yl)-1-methylpyridin-1-ium ... 4-(2-{[(6R,7R)-2-carboxylato-7-[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido …
Matched Description: … treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and …
Matched Salts name: … Ceftaroline fosamil acetate ... Ceftaroline fosamil acetate monohydrate …
Matched Iupac: … ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]sulfanyl}-1,3-thiazol-4-yl)-1-methylpyridin-1-ium ... 4-(2-{[(6R,7R)-2-carboxylato-7-[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido …
Matched Description: … treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and …
Matched Salts name: … Ceftaroline fosamil acetate ... Ceftaroline fosamil acetate monohydrate …
1-3 Sugar Ring of Pentamannosyl 6-Phosphate
Experimental
Matched Name: … 1-3 Sugar Ring of Pentamannosyl 6-Phosphate …
Matched Iupac: … -6-(hydroxymethyl)oxan-4-yl]oxy}oxan-4-yl]oxy}-3,4,5-trihydroxyoxan-2-yl]methoxy}phosphonic acid ... {[(2R,3S,4S,5S,6R)-6-{[(2R,3R,4S,5S,6R)-3,5-dihydroxy-2-(hydroxymethyl)-6-{[(2S,3S,4S,5R,6R)-2,3,5-trihydroxy …
Matched Iupac: … -6-(hydroxymethyl)oxan-4-yl]oxy}oxan-4-yl]oxy}-3,4,5-trihydroxyoxan-2-yl]methoxy}phosphonic acid ... {[(2R,3S,4S,5S,6R)-6-{[(2R,3R,4S,5S,6R)-3,5-dihydroxy-2-(hydroxymethyl)-6-{[(2S,3S,4S,5R,6R)-2,3,5-trihydroxy …
2''-O-[N-(3-(aminopropyl)2-aminoethyl]paromomycin
Experimental
Matched Name: … 2''-O-[N-(3-(aminopropyl)2-aminoethyl]paromomycin …
Matched Iupac: … ,2R,3S,5R,6S)-3,5-diamino-2-{[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}- ... (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3R,4R,5S)-4-{2-[(3-aminopropyl)amino]ethoxy}-5-{[(1R ... 6-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxolan-3-yl]oxy}oxane-3,4-diol …
Matched Iupac: … ,2R,3S,5R,6S)-3,5-diamino-2-{[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}- ... (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3R,4R,5S)-4-{2-[(3-aminopropyl)amino]ethoxy}-5-{[(1R ... 6-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxolan-3-yl]oxy}oxane-3,4-diol …
(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE
Experimental
Matched Name: … (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE …
Matched Iupac: … 1-[5-(pyridin-3-yl)furan-2-yl]methanamine …
Matched Iupac: … 1-[5-(pyridin-3-yl)furan-2-yl]methanamine …
methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate
Experimental
Matched Name: … methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate …
Matched Iupac: … methyl (3S)-3-{[(tert-butoxy)carbonyl]amino}-4-oxopentanoate …
Matched Iupac: … methyl (3S)-3-{[(tert-butoxy)carbonyl]amino}-4-oxopentanoate …
6-(3',5'-DIMETHYLBENZYL)-1-ETHOXYMETHYL-5-ISOPROPYLURACIL
Experimental
Matched Name: … 6-(3',5'-DIMETHYLBENZYL)-1-ETHOXYMETHYL-5-ISOPROPYLURACIL …
Matched Iupac: … 6-[(3,5-dimethylphenyl)methyl]-1-(ethoxymethyl)-5-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 6-[(3,5-dimethylphenyl)methyl]-1-(ethoxymethyl)-5-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE
Experimental
Matched Name: … 3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE …
Matched Iupac: … 3-(4-chlorophenyl)-5-(methylsulfanyl)-4H-1,2,4-triazole …
Matched Iupac: … 3-(4-chlorophenyl)-5-(methylsulfanyl)-4H-1,2,4-triazole …
N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE
Experimental
Matched Name: … N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE …
Matched Iupac: … ({3-[(4-chlorophenyl)carbamoyl]naphthalen-2-yl}oxy)phosphonic acid …
Matched Iupac: … ({3-[(4-chlorophenyl)carbamoyl]naphthalen-2-yl}oxy)phosphonic acid …
3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole
Experimental
Matched Name: … 3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole …
Matched Iupac: … 3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole …
Matched Iupac: … 3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole …
HYDROXY[3-(6-METHYLPYRIDIN-2-YL)PROPYL]FORMAMIDE
Experimental
Matched Name: … HYDROXY[3-(6-METHYLPYRIDIN-2-YL)PROPYL]FORMAMIDE …
Matched Iupac: … N-hydroxy-N-[3-(6-methylpyridin-2-yl)propyl]formamide …
Matched Iupac: … N-hydroxy-N-[3-(6-methylpyridin-2-yl)propyl]formamide …
Cyd dengue virus serotype 3 live (attenuated) antigen
Approved
Matched Name: … Cyd dengue virus serotype 3 live (attenuated) antigen …
Matched Mixtures name: … DENGVAXIA MD, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION ... DENGVAXIA, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION …
Matched Mixtures name: … DENGVAXIA MD, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION ... DENGVAXIA, POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION …
Cinnarizine
First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner...
Approved
Investigational
Matched Synonyms: … 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine …
Matched Iupac: … 1-(diphenylmethyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Description: … in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and ... to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting ... Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system …
Matched Salts cas: … 25332-14-3 …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers …
Matched Iupac: … 1-(diphenylmethyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Description: … in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and ... to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting ... Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system …
Matched Salts cas: … 25332-14-3 …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers …
Efinaconazole
Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis. It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North America LLC under the name Jublia.
Approved
Matched Synonyms: … (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol …
Matched Iupac: … (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol …
Matched Description: … It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North ... Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the …
Matched Categories: … Imidazole and Triazole Derivatives …
Matched Iupac: … (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol …
Matched Description: … It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North ... Efinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the …
Matched Categories: … Imidazole and Triazole Derivatives …
Brilaroxazine
Brilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. Reviva Pharmaceuticals also intends to investigate RP5063 for the treatment of bipolar disorder, major depressive disorder, psychosis/agitation associated with Alzheimer's disease, Parkinson's disease psychosis, attention deficit hyperactivity disorder...
Investigational
Matched Synonyms: … 6-(4-(4-(2,3-Dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo(b)(1,4)oxazin-3(4H)-one …
Matched Iupac: … 6-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydro-2H-1,4-benzoxazin-3-one …
Matched Description: … antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and ... Alzheimer's disease, Parkinson's disease psychosis, attention deficit hyperactivity disorder (ADD/ADHD), and …
Matched Iupac: … 6-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydro-2H-1,4-benzoxazin-3-one …
Matched Description: … antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and ... Alzheimer's disease, Parkinson's disease psychosis, attention deficit hyperactivity disorder (ADD/ADHD), and …
Entrectinib
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Synonyms: … N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and ... FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and ... This therapy offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ROZLYTREK 100 MG SERT KAPSÜL , 30 ADET …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and ... FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and ... This therapy offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ROZLYTREK 100 MG SERT KAPSÜL , 30 ADET …
4'-Thio-fac
4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and Lymphomas).
Investigational
Matched Synonyms: … 4-Amino-1-[(2R,3S,4S,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrothiophen-2-Yl] Pyrimidin-2(1H) …
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and …
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and …
BR101801
Experimental
Matched Synonyms: … 4-[[(1S)-1-(4,8-dichloro-1-oxo-2-phenylisoquinolin-3-yl)ethyl]amino]-8H-pyrido[2,3-d]pyrimidin-5-one …
Indotecan
Investigational
Matched Synonyms: … 5h-(1,3)dioxolo(4',5':5,6)indeno(1,2-c)isoquinoline-5,12(6h)-dione, 2,3-dimethoxy-6-(3-(4-morpholinyl …
Obexelimab
Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO 400-FOLD …
Ketorolac
Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain,...
Approved
Matched Iupac: … 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid …
Matched Description: … tablet, injectable, nasal spray and as an ophthalmic solution. ... Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral ... soft tissue pain, and ankylosing spondylitis. …
Matched Mixtures name: … Acunistat-30 …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Heteroaryl acetic acid NSAIDS ... Antiinflammatory and Antirheumatic Products ... Mydriatics and Cycloplegics ... phenylephrine and ketorolac …
Matched Products: … SCELTO 30 ... FARPAIN 30 ... Acunivive 30 …
Matched Description: … tablet, injectable, nasal spray and as an ophthalmic solution. ... Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral ... soft tissue pain, and ankylosing spondylitis. …
Matched Mixtures name: … Acunistat-30 …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Heteroaryl acetic acid NSAIDS ... Antiinflammatory and Antirheumatic Products ... Mydriatics and Cycloplegics ... phenylephrine and ketorolac …
Matched Products: … SCELTO 30 ... FARPAIN 30 ... Acunivive 30 …
Dazcapistat
Investigational
Matched Synonyms: … 5-oxazolecarboxamide, n-(3-amino-2,3-dioxo-1-(phenylmethyl)propyl)-4-(2-fluorophenyl)-2-methyl- ... N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2-fluorophenyl)-2-methyloxazole-5-carboxamide ... N-(3-amino-2,3-dioxo-1-(phenylmethyl)propyl)-4-(2-fluorophenyl)-2-methyl-5-oxazolecarboxamide …
Matched Iupac: … 3-{[4-(2-fluorophenyl)-2-methyl-1,3-oxazol-5-yl]formamido}-2-oxo-4-phenylbutanamide …
Matched Iupac: … 3-{[4-(2-fluorophenyl)-2-methyl-1,3-oxazol-5-yl]formamido}-2-oxo-4-phenylbutanamide …
Ropsacitinib
Investigational
Matched Synonyms: … Cyclobutaneacetonitrile, 3-cyano-1-(4-(6-(1-methyl-1h-pyrazol-4- yl)pyrazolo(1,5-a)pyrazin-4-yl)-1h-pyrazol ... Trans-3-cyano-1-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrazolo(1,5-a)pyrazin-4-yl)- 1h-pyrazol-1-yl)-cyclobutaneacetonitrile …
Matched Iupac: … (1r,3r)-3-(cyanomethyl)-3-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]-1H-pyrazol-1-yl …
Matched Iupac: … (1r,3r)-3-(cyanomethyl)-3-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]-1H-pyrazol-1-yl …
Displaying drugs 4376 - 4400 of 5277 in total