Displaying drugs 4376 - 4400 of 11617 in total
AV-COVID-19
AV-COVID-19 is a vaccine composed of autologous dendritic cells loaded with SARS-CoV-2 antigens and with or without Granulocyte-macrophage colony-stimulating factor (GM-CSF).
The vaccine is created from the receiving patients’ isolated peripheral blood monocytes. The monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2...
Investigational
Matched Description: … AV-COVID-19 is a vaccine composed of autologous dendritic cells loaded with SARS-CoV-2 antigens and with …
LY-2090314
Ly2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
Investigational
Matched Iupac: … piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.0^{4,13}]trideca-2,4,6,8(13)-tetraen-3-yl]-4-{imidazo[1,2-a] …
IPI-493
IPI-493 has been used in trials studying the treatment of Advanced Malignancies.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Tanespimycin
Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90). It is developed for the treatment of several types of cancer, solid tumors or chronic myelogenous leukemia.
Investigational
Matched Description: … of heat shock protein 90 (HSP90). ... Tanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor …
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Retaspimycin
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
XL-888
XL888 has been used in trials studying the treatment of Cancer and Melanoma.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
7-Hydroxystaurosporine
Experimental
Investigational
AUY922
AUY922 has been used in trials studying the treatment of Lymphoma, Breast Cancer, Metastatic Disease, Advanced Solid Tumors, and Hematologic Neoplasms, among others.
Investigational
Matched Categories: … HSP90 Heat-Shock Proteins, antagonists & inhibitors …
Staurosporine
An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Experimental
Matched Description: … An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses …
MK-8245
MK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus.
Investigational
Matched Categories: … Stearoyl-CoA Desaturase, antagonists & inhibitors …
LB-001
LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA mutase (MUT) gene into the genome of patients with methylmalonic acidemia.
Investigational
Matched Description: … LB-001 is a gene editing therapy designed to incorporate a functioning version of the faulty methylmalonyl-COA …
Arimoclomol
Arimoclomol is an experimental drug compound developed by CytRx Corporation, a biopharmaceutical company based in Los Angeles, California. The orally administered drug is intended to treat amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a neurodegenerative disease with no effective treatment.
Investigational
Matched Description: … Arimoclomol is an experimental drug compound developed by CytRx Corporation, a biopharmaceutical company ... drug is intended to treat amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a …
Calcium hypochlorite
Experimental
Matched Mixtures name: … POLYLAB T-EUSOL (SOLUTION A & B) ... SC Pharma Eusol Solution Max A & B ... POLYLAB T-EUSOL( SOLUTION A & B) …
K-252a
Experimental
Meglutol
An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
Experimental
Matched Description: … as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting ... interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A …
DiaPep 277
DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460).
Investigational
Matched Description: … DiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460). …
Matched Categories: … Heat-Shock Proteins …
Matched Categories: … Heat-Shock Proteins …
Xylitol
Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many fruits and vegetables. Xylitol-rich plant materials include birch and beechwood . It is widely used as a sugar substitute and in "sugar-free" food products. The effects of xylitol on dental caries have been widely studied,...
Experimental
Investigational
Matched Description: … It is widely used as a sugar substitute and in "sugar-free" food products. ... Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many ... Xylitol is a non-fermentable sugar alcohol by most plaque bacteria, indicating that it cannot be fermented …
Matched Mixtures name: … Fluor-a-day ... Fluor-a-day ... Fluor-a-day …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Fluor-a-day ... Fluor-a-day ... Fluor-a-day …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Anti-SARS-CoV-2 REGN-COV2
Anti-SARS-COV-2 REGN-COV2 is a combination of novel antibodies designed by Regeneron for both the prevention and treatment of SARS-COV-2, the virus that causes COVID-19. This drug is a combination of the antibodies REGN10933 and REGN10987, derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered...
Investigational
Matched Description: … Anti-SARS-COV-2 REGN-COV2 is a combination of novel antibodies designed by Regeneron for both the prevention ... This drug is a combination of the antibodies REGN10933 and REGN10987, derived from humanized VelocImmune …
Omburtamab
CD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours.[A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are currently under clinical development for use in various cancers. Omburtamab is under investigation in clinical trial NCT03275402 (131i-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous...
Investigational
Matched Description: … CD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours …
Garadacimab
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy ... on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a …
AG-702
AG-702 is a recombinant human heat shock protein also known as stress protein. It is also known as HSPs, which are a group of proteins that are induced when a cell undergoes various types of environmental stresses like heat, cold and oxygen deprivation. HSPs are present in all cells in...
Investigational
Matched Description: … AG-702 is a recombinant human heat shock protein also known as stress protein. ... It is also known as HSPs, which are a group of proteins that are induced when a cell undergoes various ... types of environmental stresses like heat, cold and oxygen deprivation. …
p-Coumaric acid
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Dimiracetam
Dimiracetam has been used in trials studying the treatment of AIDS, Neuropathy, and Acquired Immunodeficiency Syndrome.
Investigational
Matched Iupac: … hexahydro-1H-pyrrolo[1,2-a]imidazole-2,5-dione …
CEP-1347
CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults leading to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and after transplantation.
Investigational
Matched Description: … CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults …
Displaying drugs 4376 - 4400 of 11617 in total