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Displaying drugs 4426 - 4450 of 5619 in total
RH-1 has been used in trials studying the treatment of Advanced Solid Tumors and Non-Hodgkin's Lymphoma.
Experimental
Investigational
Matched Synonyms: … 2,5-Cyclohexadiene-1,4-dione, 2,5-bis(1-aziridinyl)-3-(hydroxymethyl)-6-methyl- …
Matched Iupac: … 2,5-bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione …
Matched Description: … RH-1 has been used in trials studying the treatment of Advanced Solid Tumors and Non-Hodgkin's Lymphoma …
Investigational
Matched Synonyms: … 3-((2-Aminoethoxy)imino)-5alpha-androstan-6,17-dione …
Matched Iupac: … (3aS,3bR,5aS,9aR,9bS,11aS)-7-[(2-aminoethoxy)imino]-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene …
Matched Salts name: … Istaroxime hydrochloride
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Investigational
Matched Synonyms: … Ad5/3-D24-granulocyte-macrophage colony stimulating factor (GMCSF)-encoding oncolytic adenovirus …
Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Synonyms: … 1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine …
Matched Iupac: … dimethyl(2-{5-[(pyrrolidine-1-sulfonyl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and ... stopping the release of certain natural substances that cause pain, nausea, and other symptoms of migraine …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist ... Monoamine Oxidase A Substrates …
Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Synonyms: … beta-Quinine ... (R)-(6-Methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol …
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. ... [A38016] It prolongs cellular action potential by blocking sodium and potassium currents. …
Matched Salts cas: … 7054-25-3 ... 27555-34-6 …
Matched Salts name: … Quinidine hydrochloride
Matched Categories: … Quinine and stereoisomer ... Metabolic Side Effects of Drugs and Substances ... Medications that reduce magnesium levels ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Investigational
Matched Synonyms: … (5-amino-1-(4-fluoro-phenyl)-1h-pyrazol-4-yl)-(3-(2,3-dihydroxy-propoxy)-phenyl)-methanone ... [5-Amino-1-(4-fluoro-phenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxy-propoxy)-phenyl]-methanone ... Methanone, (5-amino-1-(4-fluorophenyl)-1h-pyrazol-4-yl)(3-(2,3-dihydroxypropoxy)phenyl)- …
Matched Iupac: … 3-{3-[5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbonyl]phenoxy}propane-1,2-diol …
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to DB00169 (vitamin D3)...
Approved
Nutraceutical
Matched Synonyms: … 1-alpha-25-Dihydroxyvitamin D3 ... (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol ... (1α,,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol …
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden- …
Matched Description: … In addition to promoting fatty acid synthesis and inhibiting lipolysis, calcitriol has been demonstrated ... Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred ... reabsorption of calcium in the kidneys, and stimulating the release of calcium stores from the skeletal …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Vitamins (Fat Soluble) ... Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Vitamin D and Analogues …
Matched Products: … SILKIS OINTMENT 3 mcg/g ... QALYVİZ 0.5 MCG YUMUŞAK KAPSÜL, 30 ADET ... QALYVİZ 0.25 MCG YUMUŞAK KAPSÜL, 30 ADET …
Experimental
Matched Name: … 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine …
Matched Iupac: … 5-[(3R)-3-{5-methoxy-3',5'-dimethyl-[1,1'-biphenyl]-3-yl}but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine …
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Synonyms: … 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... ±-3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... bendroflumethiazide and potassium ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... bendroflumethiazide and potassium-sparing agents …
Experimental
Matched Name: … 1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE …
Matched Iupac: … {[(2R,3S,5R)-3-hydroxy-5-(4-methyl-1H-indol-1-yl)oxolan-2-yl]methoxy}phosphonic acid
Experimental
Matched Name: … 1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-5-NITRO-1H-INDOLE …
Matched Iupac: … {[(2R,3S,5R)-3-hydroxy-5-(5-nitro-1H-indol-1-yl)oxolan-2-yl]methoxy}phosphonic acid
Experimental
Matched Name: … (1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone …
Matched Iupac: … (3-{[3-methyl-2-(1-methyl-1H-imidazole-2-carbonyl)-1-benzofuran-4-yl]oxy}propyl)[(pyridin-3-yl)methyl …
Experimental
Matched Name: … 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol …
Matched Iupac: … 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}-[1,2]oxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol …
Iberdomide (CC-220) has been used in trials studying the treatment of Systemic Lupus Erythematosus.
Investigational
Matched Synonyms: … )-, (3S)- ... (S)-3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione ... 2,6-Piperidinedione, 3-(1,3-dihydro-4-((4-(4-morpholinylmethyl)phenyl)methoxy)-1-oxo-2H-isoindol-2-yl …
Matched Iupac: … (3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6 …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic ... Phthalic Acids
Experimental
Matched Name: … 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE …
Matched Iupac: … (2R,3R,4S,5R)-2-{4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-methyloxolane-3,4-diol …
Experimental
Matched Name: … (4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile …
Matched Iupac: … (4'R)-7'-chloro-9'-methyl-1'-oxo-1',2',4',9'-tetrahydrospiro[piperidine-4,3'-pyrido[3,4-b]indole]-4'- …
Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used...
Approved
Experimental
Matched Synonyms: … Betula pendula/pubescens bark …
Matched Description: … Some of the compounds identified in it include betulin, [lupeol], [betulinic acid], oleanolic acid, and ... Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities ... [A249945] Birch bark extract is obtained from the white part of the birch tree bark, and the main species …
MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Synonyms: … -thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide ... (1'R,4R)-2-(2,2,2-trifluoroethyl)-5'-[(E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-enyl]spiro[1,2,5 …
Matched Iupac: … (1'R,3R,10'S)-5-(2,2,2-trifluoroethyl)-5'-[(1E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-en-1-yl]spiro ... [1lambda6,2,5-thiadiazolidine-3,13'-tricyclo[8.2.1.0^{3,8}]tridecane]-3'(8'),4',6'-triene-1,1-dione …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators ... Heterocyclic Oxides ... Amyloid Precursor Protein Secretases, antagonists & inhibitors …
Experimental
Matched Synonyms: … N-{(2R)-2-Cyclohexyl-2-[(diaminomethylene)amino]acetyl}glycyl-N-(3-sulfanylpropyl)-L-alaninamide …
Matched Name: … 2-[2-(2-Cyclohexyl-2-guanidino-acetylamino)-acetylamino]-N-(3-mercapto-propyl)-propionamide …
Matched Iupac: … (2S)-2-{2-[(2R)-2-cyclohexyl-2-[(diaminomethylidene)amino]acetamido]acetamido}-N-(3-sulfanylpropyl)propanamide …
Experimental
Matched Synonyms: … 3-Tetradecyloxy-1,2-propanediol …
Matched Iupac: … 3-(tetradecyloxy)propane-1,2-diol …
Nifekalant is under investigation in clinical trial NCT03855826 (Evaluation of the Efficacy and Safety of Nifekalant Hydrochloride (NIF) Injection).
Investigational
Matched Synonyms: … 6-((2-((2-Hydroxyethyl)(3-(p-nitrophenyl)propyl)amino)ethyl)amino)-1,3-dimethyluracil …
Matched Iupac: … 6-({2-[(2-hydroxyethyl)[3-(4-nitrophenyl)propyl]amino]ethyl}amino)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine …
Matched Description: … Nifekalant is under investigation in clinical trial NCT03855826 (Evaluation of the Efficacy and Safety ... of Nifekalant Hydrochloride (NIF) Injection). …
Matched Salts name: … Nifekalant hydrochloride
Investigational
Matched Synonyms: … (S)-2-hydroxy-6-((4-(2-(2-hydroxyethyl)nicotinoyl)morpholin- 3-yl)methoxy)benzaldehyde …
Matched Iupac: … 2-hydroxy-6-{[(3S)-4-[2-(2-hydroxyethyl)pyridine-3-carbonyl]morpholin-3-yl]methoxy}benzaldehyde …
Investigational
Matched Synonyms: … 3-aminophthalic hydrazide …
Matched Categories: … Indicators and Reagents …
Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione....
Approved
Matched Synonyms: … 3-Hydroxy-1,3,5(10)-estratrien-17-one …
Matched Iupac: … (3aS,3bR,9bS,11aS)-7-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Description: … Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and ... It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue ... Estrone may be further metabolized to 16-alpha-hydroxyestrone, which may be reduced to estriol by estradiol …
Matched Categories: … Genito Urinary System and Sex Hormones ... Natural and Semisynthetic Estrogens, Plain ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection.
Approved
Investigational
Matched Synonyms: … N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet) …
Matched Description: … Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia ... hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat
Matched Salts name: … Tesamorelin acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Nerve Tissue Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Pituitary and Hypothalamic Hormones and Analogues …
Displaying drugs 4426 - 4450 of 5619 in total