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Displaying drugs 4526 - 4550 of 10619 in total

Smilagenin

Smilagenin is a novel non-peptide, orally bioavailable neurotrophic factor inducer that readily reverses free radical neurotoxicity produced by 1-ethyl-4- phenylpyridium (MPP+) in dopaminergic neurones and reverses the decrease of neuronal growth factors and dopamine receptors in the brain. Pre-clinical work with smilagenin showed it to be neuroprotective against betya-amyloid and...
Investigational
Matched Iupac: … (1'R,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'S,16'S,18'R)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo …
Matched Description: … of neural connections. ... with ageing of the brain. ... P58 is one of a family of phytochemicals isolated from traditional treatments for the elderly that have …

Terbutryn

Experimental

Ruscogenin

Experimental
Matched Iupac: … (1'S,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'R,14'R,16'R)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo …

Calcium

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Nutraceutical
Matched Description: … Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, ... Low calcium intake may also be a risk factor in the development of osteoporosis. ... The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. …
Matched Mixtures name: … Herbs of Gold B Complex Plus Softgel ... Kordel"s Bio-Liquid Women"s Multi With Fish Oil Vegicap ... KORDEL`S EXECUTIVE B TABLET …
Matched Categories: … Drugs for Treatment of Bone Diseases …

AZD3409

AZD3409 is a farnesyl-transferase inhibitor (FAR) indicated for the treatment of solid tumors. Phase I trials were initiated January 2003, and were ongoing as of February 2004. As of February 2007 the development of AZD3409 had been discontinued.
Investigational
Matched Description: … As of February 2007 the development of AZD3409 had been discontinued. ... Phase I trials were initiated January 2003, and were ongoing as of February 2004. ... AZD3409 is a farnesyl-transferase inhibitor (FAR) indicated for the treatment of solid tumors. …

Trifluoroacetonyl coenzyme A

Experimental

4-hydroxyphenacyl coenzyme A

Experimental

Evening primrose oil

Evening primrose oil comes from the extraction from Oenothera biennis seeds and it is commonly used as an alternative source for omega-6 essential fatty acids. In its composition it presents some fatty acids such as DB00132 and DB13854. Evening primrose oil has been filled for the FDA by Humanetics Corporation...
Investigational
Nutraceutical
Matched Description: … April 2000 to be a new dietary ingredient but its current status is "Inadequate basis for expectation of …
Matched Mixtures name: … Kordel"s CoQ10 75MG + Omega 3-6 Capsules ... WOMEN`S MULTIVITE WITH EVENING PRIMROSE OIL,ROYAL JELLY & KOREAN GINSENG …
Matched Products: … GNC WOMEN"S Evening Primrose Oil 500mg Softgel …

Meladrazine

Experimental

Tosatoxumab

Tosatoxumab is a fully-human monoclonal antibody (IgG1λ) targeting the Staphylococcus aureus alpha-toxin or the S. aureus alpha-hemolysin[A191829, L31568, L31573] and thereby preserving human immune cells by protecting against destruction of host cells mediated by the toxin.
Investigational
Matched Description: … is a fully-human monoclonal antibody (IgG1λ) targeting the Staphylococcus aureus alpha-toxin or the S. ... A191829, L31568, L31573] and thereby preserving human immune cells by protecting against destruction of …

2-carboxypropyl-coenzyme A

Experimental

4-hydroxybenzyl coenzyme A

Experimental

Amino acids

Mixture of amino acids ; used for parenteral nutrition in infants.
Investigational
Matched Description: … Mixture of amino acids ; used for parenteral nutrition in infants. …
Matched Mixtures name: … Ari S-Liner …
Matched Products: … GNC MEN"S MEGA MEN ACTIVE TABLET …

Methyl Methylsulfinylmethyl Sulfide

Experimental
Matched Iupac: … [(S)-methanesulfinyl](methylsulfanyl)methane …

ENMD-981693

Investigational

(R)-warfarin

Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.
Experimental
Matched Description: … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared ... S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A1038] …

Witch hazel

Nutraceutical
Matched Products: … A Breath of Fresh Air …

Clobutinol

Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in some patients.
Withdrawn
Matched Description: … In 2007, Clobutinol was determined to cause cardiac arrhythmia in some patients. …

AR-9281

AR-9281 inhibits soluble epoxide hydrolase.
Investigational

Elacridar

Elacridar (GW120918) is an oral bioenhancer that targets multiple drug resistance in tumors. In many cases, the appearance of multidrug resistance in cancer is due to a change in expression of protein inhibitors. As of August 2007 elacridar was not listed on GSK's product pipeline. Development is assumed to have...
Investigational
Matched Description: … As of August 2007 elacridar was not listed on GSK's product pipeline. ... In many cases, the appearance of multidrug resistance in cancer is due to a change in expression of protein …

CHGN111

CHGN111 is an inhibitor of the mitochondrial enzyme CLK-1 which is a demethoxyubiquinone hydroxylase. Numerous parameters of mitochondrial function are altered when the activity of CLK-1 is reduced, which results in a decrease of ROS at critical cellular sites, as well as in a decrease of systemic oxidative stress. It...
Investigational
Matched Description: … It was under investigation until approximately 2007. ... Numerous parameters of mitochondrial function are altered when the activity of CLK-1 is reduced, which ... results in a decrease of ROS at critical cellular sites, as well as in a decrease of systemic oxidative …

Maropitant

Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats.
Vet approved
Matched Description: … , is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of ... It was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use …

Isopropyl beta-D-thiogalactopyranoside

A non-metabolizable galactose analog that induces expression of the LAC operon.
Experimental
Matched Description: … A non-metabolizable galactose analog that induces expression of the LAC operon. …

Artefenomel

Artefenomel has been investigated for the treatment of Malaria.
Investigational
Matched Iupac: … 4-(2-{4-[(4's,4''s)-dispiro[adamantane-2,2'-[1,3,5]trioxolane-4',1''-cyclohexane]-4''-yl]phenoxy}ethyl …
Matched Description: … Artefenomel has been investigated for the treatment of Malaria. …

GTX-102

GTX-102 is an antisense oligonucleotide designed to target and inhibit the expression of UBE3A-AS. It is being investigated for the treatment of Angelman Syndrome.
Investigational
Matched Description: … It is being investigated for the treatment of Angelman Syndrome.[L46772] ... GTX-102 is an antisense oligonucleotide designed to target and inhibit the expression of UBE3A-AS. …
Matched Categories: … Antisense Oligonucleotide Specific to the Antisense Transcript of UBE3A …
Displaying drugs 4526 - 4550 of 10619 in total