Displaying drugs 4551 - 4575 of 5871 in total
Elebsiran
Elebsiran is under investigation in clinical trial NCT05461170 (SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.).
Investigational
Matched Description: … Elebsiran is under investigation in clinical trial NCT05461170 (SOLSTICE: Combination Therapy for the Treatment …
Emoxypine
Emoxypine is under investigation in clinical trial NCT06221826 (MEXIDOL® in the Rehabilitation Treatment of Patients With Acute Cerebral Failure).
Investigational
Matched Description: … Emoxypine is under investigation in clinical trial NCT06221826 (MEXIDOL® in the Rehabilitation Treatment …
BI-K0376
BI-K0376 is investigated for use/treatment in acne. BI-K0376 is a solid. It is under investigation by Pfizer and has gone through phase I of the clinical trails.
Investigational
Matched Description: … BI-K0376 is investigated for use/treatment in acne. BI-K0376 is a solid. …
Carmofur
Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
Withdrawn
Matched Description: … Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment …
Sotrastaurin
Sotrastaurin has been used in trials studying the basic science and treatment of Uveal Melanoma, Richter Syndrome, Prolymphocytic Leukemia, Recurrent Mantle Cell Lymphoma, and Recurrent Small Lymphocytic Lymphoma, among others.
Investigational
Matched Description: … Sotrastaurin has been used in trials studying the basic science and treatment of Uveal Melanoma, Richter …
Bemegride
Bemegride is a CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.
Experimental
Matched Description: … It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose. …
ST-36
ST-36 is a cell-penetrating dominant-negative form of activating transcription factor 5. In 2017, it received orphan drug designation by the FDA for the treatment of glioma.
Investigational
Matched Description: … In 2017, it received orphan drug designation by the FDA for the treatment of glioma.[L47341] …
AUTO3
AUTO3 is bicistronic chimeric antigen receptor T-cell therapy investigated for acute lymphoblastic leukemia (ALL). It is an investigational chimeric antigen receptor (CAR) T cell treatment targeting CD19 and CD22.
Investigational
Matched Description: … It is an investigational chimeric antigen receptor (CAR) T cell treatment targeting CD19 and CD22. …
ALMB-0166
ALMB-0166 is a umanized connexin 43 (Cx43) monoclonal antibody being investigated for the treatment of acute spinal cord injury. It was granted FDA orphan designation in November 2018.
Investigational
Matched Description: … ALMB-0166 is a umanized connexin 43 (Cx43) monoclonal antibody being investigated for the treatment of …
Melperone
Melperone is an atypical antipsychotic of the butyrophenone chemical class, making it structurally related to the typical antipsychotic haloperidol. Melperone has been used for a span of greater than 30 years in the European Union . It has been well established in the treatment of confusion, anxiety, restlessness (particularly in...
Investigational
Matched Description: … Recently, it has been studied as a treatment of psychosis related to Parkinson's disease [L1316]. ... It has been well established in the treatment of confusion, anxiety, restlessness (particularly in the …
Aminopterin
Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia. In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment...
Investigational
Withdrawn
Matched Description: … Off label, aminopterin has also been used in the treatment of psoriasis. ... Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment …
CG7870
CG7870 is an oncolytic virus therapy for prostate cancer. It is a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer.
Investigational
Matched Description: … It is a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment …
Peptide YY (3-36)
Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity. It reduces appetite and increases satiety in obese patients.
Investigational
Matched Description: … Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity …
AT-7519
AT7519 is a selective inhibitor of certain Cyclin Dependent Kinases (CDKs) leading to tumour regression. It is developed by Astex for the treatment of solid tumours and haematological malignancies.
Investigational
Matched Description: … It is developed by Astex for the treatment of solid tumours and haematological malignancies. …
Ponazuril
Ponazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for the treatment of equine protozoal myeloencephalitis in horses, caused by Sarcocystis neurona.
Vet approved
Matched Description: … Ponazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for the treatment …
Berzosertib
Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.
Investigational
Matched Description: … Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous …
Sonolisib
Sonolisib has been used in trials studying the treatment of Glioblastoma, Prostate Cancer, Advanced Solid Tumors, Advanced BRAF-mutant Cancers, and Non Small Cell Lung Cancer (NSCLC), among others.
Investigational
Matched Description: … Sonolisib has been used in trials studying the treatment of Glioblastoma, Prostate Cancer, Advanced Solid …
AMP-201
AMP-201 comprises an adeno-associated virus type 8 vector (AAV8) encoding the collagen Q gene (COLQ). It is under investigation for the treatment of collagen Q congenital myasthenia.
Investigational
Matched Description: … It is under investigation for the treatment of collagen Q congenital myasthenia. …
HTPEP-001
HTPEP-001 is a novel peptide that works to inhibit the activation of transforming growth factor beta (TGF-β). It is being investigated for the treatment of fibrosis.
Investigational
Matched Description: … It is being investigated for the treatment of fibrosis.[A263527] …
CX-717
CX-717 is an ampakine compound previously investigated for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and Alzheimer's disease.
Illicit
Investigational
Matched Description: … CX-717 is an ampakine compound previously investigated for the treatment of Attention-Deficit/Hyperactivity …
MIV-701
MIV-701 is a selective, potent inhibitor of the protease Cathepsin K. It is developed for the treatment of osteoporosis.
Investigational
Matched Description: … It is developed for the treatment of osteoporosis. …
Conatumumab
Conatumumab has been used in trials studying the treatment of Sarcoma, Lymphoma, Oncology, Colon Cancer, and Rectal Cancer, among others.
Investigational
Matched Description: … Conatumumab has been used in trials studying the treatment of Sarcoma, Lymphoma, Oncology, Colon Cancer …
Epacadostat
Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others.
Investigational
Matched Description: … Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma …
Basimglurant
Basimglurant has been used in trials studying the diagnostic and treatment of Depression, Fragile X Syndrome, and Major Depressive Disorder.
Investigational
Matched Description: … Basimglurant has been used in trials studying the diagnostic and treatment of Depression, Fragile X Syndrome …
ZD-6126
ZD6126 has been used in trials studying the treatment of Kidney Neoplasms, Colorectal Neoplasms, Metastases, Neoplasm, and Carcinoma, Renal Cell.
Investigational
Matched Description: … ZD6126 has been used in trials studying the treatment of Kidney Neoplasms, Colorectal Neoplasms, Metastases …
Displaying drugs 4551 - 4575 of 5871 in total