Displaying drugs 4601 - 4625 of 5430 in total
MAX-40279
MAX-40279 is under investigation in clinical trial NCT03412292 (MAX-40279 in Subjects With Acute Myelogenous Leukemia (AML)).
Investigational
Matched Synonyms: … 7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-(1-(piperidin-4-yl)-1H-pyrazol-4-yl) thieno (3,2-d)pyrimidin- …
Matched Iupac: … N-[7-(4-fluoro-2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimidin-2-yl]-1-(piperidin-4-yl)-1H-pyrazol-4- …
Matched Iupac: … N-[7-(4-fluoro-2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimidin-2-yl]-1-(piperidin-4-yl)-1H-pyrazol-4- …
Nipocalimab
Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia).
Investigational
Matched Synonyms: … .-1 chain), disulfide with human monoclonal m281 .lambda.-chain, dimer …
Matched Description: … Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults …
Matched Description: … Nipocalimab is under investigation in clinical trial NCT04119050 (Efficacy and Safety of M281 in Adults …
Belrestotug
Belrestotug is under investigation in clinical trial NCT05565378 (A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/metastatic Non-small-cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tigit) (human monoclonal eos884448 .gamma.1-chain), disulfide …
Zidovudine
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator...
Approved
Matched Iupac: … 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced ... It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves ... Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia …
Matched Mixtures name: … LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) ... LAMIVUDIN/ZID PUR 150/300 ... LAMIVUDIN/ZIDO HEU 150/300 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... zidovudine and lamivudine ... zidovudine, lamivudine and abacavir ... zidovudine, lamivudine and nevirapine ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … ยาเม็ดซิโดวูดีน 300 มิลลิกรัม ... CIPLAZIDOVIR 300 TABLETAS ... ZIDOVUDINA 300 MG TABLETAS …
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced ... It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves ... Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia …
Matched Mixtures name: … LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) ... LAMIVUDIN/ZID PUR 150/300 ... LAMIVUDIN/ZIDO HEU 150/300 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... zidovudine and lamivudine ... zidovudine, lamivudine and abacavir ... zidovudine, lamivudine and nevirapine ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … ยาเม็ดซิโดวูดีน 300 มิลลิกรัม ... CIPLAZIDOVIR 300 TABLETAS ... ZIDOVUDINA 300 MG TABLETAS …
(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE
Experimental
Matched Name: … (2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN …
Matched Iupac: … (2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-[(1r,4S)-4-{[1,2,4]triazolo[1,5- …
Matched Iupac: … (2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-[(1r,4S)-4-{[1,2,4]triazolo[1,5- …
(2R,4S)-2-[(1R)-1-{[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
Experimental
Matched Synonyms: … (2R,4S)-2-[(1R)-1-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine …
Matched Name: … (2R,4S)-2-[(1R)-1-{[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine …
Matched Iupac: … (2R,4S)-2-[(1R)-1-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine …
Matched Name: … (2R,4S)-2-[(1R)-1-{[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine …
Matched Iupac: … (2R,4S)-2-[(1R)-1-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine …
Dexamethasone palmitate
Dexamethasone palmitate is under investigation in clinical trial NCT05693467 (Preemptive Co-infiltration of Dexamethasone Palmitate With Ropivacaine for Postoperative Pain in Major Spinal Surgery).
Investigational
Matched Synonyms: … 9-fluoro-11,17-dihydroxy-16-methyl-21-((1- oxohexadecyl)oxy)pregna-1,4-diene-3,20-dione (11.beta.,16. …
4-{[(2R,3S,4R,5S)-4-(4-Chloro-2-Fluoro-Phenyl)-3-(3-Chloro-2-Fluoro-Phenyl)-4-Cyano-5-(2,2-Dimethyl-Propyl)-Pyrrolidine-2-Carbonyl]-Amino}-3-Methoxy-Benzoic Acid
Experimental
Matched Name: … 4-{[(2R,3S,4R,5S)-4-(4-Chloro-2-Fluoro-Phenyl)-3-(3-Chloro-2-Fluoro-Phenyl)-4-Cyano-5-(2,2-Dimethyl-Propyl ... )-Pyrrolidine-2-Carbonyl]-Amino}-3-Methoxy-Benzoic Acid …
Ouabain
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Approved
Matched Synonyms: … 3-(α-L-rhamnopyranosyloxy)-1β,5β,11α,14,19-pentahydroxy-5β-card-20(22)-enolide …
Matched Iupac: … 4-[(1R,3aS,3bR,5aS,7S,9R,9aR,9bS,10R,11aR)-3a,5a,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-{[ ... (2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-hexadecahydro-1H-cyclopenta[a]phenanthren-1- …
Matched Description: … gratus and other plants of the Apocynaceae; used like digitalis. ... A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus …
Matched Iupac: … 4-[(1R,3aS,3bR,5aS,7S,9R,9aR,9bS,10R,11aR)-3a,5a,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-{[ ... (2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-hexadecahydro-1H-cyclopenta[a]phenanthren-1- …
Matched Description: … gratus and other plants of the Apocynaceae; used like digitalis. ... A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus …
gamma-Hydroxybutyric acid
Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is...
Approved
Illicit
Investigational
Matched Synonyms: … 3-carboxypropoxy acid …
Matched Description: … It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem ... naturally occurring substance found in the central nervous system, wine, beef, small citrus fruits and …
Matched Salts cas: … 82316-98-1 …
Matched Description: … It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem ... naturally occurring substance found in the central nervous system, wine, beef, small citrus fruits and …
Matched Salts cas: … 82316-98-1 …
Blarcamesine
Investigational
Matched Synonyms: … Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanemethanamine …
Matched Iupac: … [(2,2-diphenyloxolan-3-yl)methyl]dimethylamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … [(2,2-diphenyloxolan-3-yl)methyl]dimethylamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
[(2R,3S,4R,5R)-5-(4-acetonyl-3-carbamoyl-pyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphate
Experimental
Matched Name: … [(2R,3S,4R,5R)-5-(4-acetonyl-3-carbamoyl-pyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl ... [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] …
Matched Iupac: … 1-[(2R,3R,4S,5R)-5-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy ... -1-ylium ... )phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-4-(2-oxopropyl)-1lambda5-pyridin …
Matched Iupac: … 1-[(2R,3R,4S,5R)-5-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy ... -1-ylium ... )phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-4-(2-oxopropyl)-1lambda5-pyridin …
Carbenicillin
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Synonyms: … N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid ... (2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Iupac: … (2S,5R,6R)-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Matched Categories: … Sulfur Compounds …
Matched Iupac: … (2S,5R,6R)-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Matched Categories: … Sulfur Compounds …
1-(2-Ethanone)-2-Hydroxy-2-(1-Amino-2-Methyl-2-Ethanol)-4-(2-Dimethyl)Ethane-Imidazoline-5-One;Chromophore (Thr-Leu-Gly)
Experimental
Matched Name: … 1-(2-Ethanone)-2-Hydroxy-2-(1-Amino-2-Methyl-2-Ethanol)-4-(2-Dimethyl)Ethane-Imidazoline-5-One;Chromophore …
Matched Iupac: … 2-[(2R)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-2-hydroxy-4-(2-methylpropyl)-5-oxo-2,5-dihydro-1H-imidazol ... -1-yl]acetaldehyde …
Matched Iupac: … 2-[(2R)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-2-hydroxy-4-(2-methylpropyl)-5-oxo-2,5-dihydro-1H-imidazol ... -1-yl]acetaldehyde …
Nicergoline
An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
Approved
Investigational
Matched Synonyms: … (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridinecarboxylate (ester) ... 10-methoxy-1,6-dimethylergoline-8β-methanol 5-bromonicotinate …
Matched Iupac: … -tetraen-4-yl]methyl 5-bromopyridine-3-carboxylate ... [(2S,4R,7R)-2-methoxy-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14 …
Matched Description: … An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. …
Matched Categories: … Ergot Alkaloids and Derivatives ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … ไนเซอร์ 10 ... ไนเซอไลน์-10 ... SERMION (10 MG) …
Matched Iupac: … -tetraen-4-yl]methyl 5-bromopyridine-3-carboxylate ... [(2S,4R,7R)-2-methoxy-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14 …
Matched Description: … An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. …
Matched Categories: … Ergot Alkaloids and Derivatives ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … ไนเซอร์ 10 ... ไนเซอไลน์-10 ... SERMION (10 MG) …
Elzovantinib
Elzovantinib is under investigation in clinical trial NCT03993873 (Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in MET).
Investigational
Matched Synonyms: … 1,15-Etheno-1H-pyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecine-12-carbonitrile, 3-amino-14-ethyl ... -11-fluoro-4,5,6,7,13,14-hexahydro-7-methyl-4-oxo-, (7S)- …
Cemdomespib
Cemdomespib is under investigation in clinical trial NCT05895552 (A Phase 2 Study of RTA 901 in Patients With Diabetic Peripheral Neuropathic Pain (CYPRESS)).
Investigational
Matched Synonyms: … -l-lyxo-hexopyranosyl)oxy)-3'-fluoro(1,1'-biphenyl)-2-yl)ethyl)- …
Cyclobenzaprine
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Synonyms: … (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amine …
Matched Iupac: … dimethyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}propyl)amine …
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Mixtures name: … Cyclo/Gaba 10/300 Pack …
Matched Products: … FLESSİ 10 MG FİLM KAPLI TABLET, 30 ADET ... SPAZBEN 10 MG FİLM KAPLI TABLET, 30 ADET ... FLESSİ 5 MG FİLM KAPLI TABLET, 30 ADET …
Matched Iupac: … dimethyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}propyl)amine …
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Mixtures name: … Cyclo/Gaba 10/300 Pack …
Matched Products: … FLESSİ 10 MG FİLM KAPLI TABLET, 30 ADET ... SPAZBEN 10 MG FİLM KAPLI TABLET, 30 ADET ... FLESSİ 5 MG FİLM KAPLI TABLET, 30 ADET …
1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene
Experimental
Matched Name: … 1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene …
Matched Iupac: … 1-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-(2,4,4-trimethylpentan-2-yl)benzene …
Matched Iupac: … 1-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-(2,4,4-trimethylpentan-2-yl)benzene …
N-[(1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)-2-propanyl]acetamide
Experimental
Matched Name: … N-[(1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)-2-propanyl]acetamide …
Matched Iupac: … N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide …
Matched Iupac: … N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide …
N-Hydroxy-1-(4-Methoxyphenyl)Sulfonyl-4-Benzyloxycarbonyl-Piperazine-2-Carboxamide
Experimental
Matched Name: … N-Hydroxy-1-(4-Methoxyphenyl)Sulfonyl-4-Benzyloxycarbonyl-Piperazine-2-Carboxamide …
Matched Iupac: … benzyl (3R)-3-(hydroxycarbamoyl)-4-(4-methoxybenzenesulfonyl)piperazine-1-carboxylate …
Matched Iupac: … benzyl (3R)-3-(hydroxycarbamoyl)-4-(4-methoxybenzenesulfonyl)piperazine-1-carboxylate …
(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide
Experimental
Matched Name: … (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-[2-(cyclopentylamino)acetyl]pyrrolidine-2-carboxamide …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-[2-(cyclopentylamino)acetyl]pyrrolidine-2-carboxamide …
1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE
Experimental
Matched Name: … 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE …
Matched Iupac: … 1-[(2-hydroxyethoxy)methyl]-5-(phenylsulfanyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 1-[(2-hydroxyethoxy)methyl]-5-(phenylsulfanyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
(R)-1-(4-(4-(Hydroxymethyl)-1,3,2-dioxaborolan-2-YL)phenethyl)guanidine
Experimental
Matched Name: … (R)-1-(4-(4-(Hydroxymethyl)-1,3,2-dioxaborolan-2-YL)phenethyl)guanidine …
(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide
Experimental
Matched Name: … (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-[2-(cyclopentyloxy)acetyl]pyrrolidine-2-carboxamide …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-[2-(cyclopentyloxy)acetyl]pyrrolidine-2-carboxamide …
Displaying drugs 4601 - 4625 of 5430 in total