Displaying drugs 451 - 475 of 1919 in total
Otlertuzumab
Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human cd antigen cd37) (synthetic human-mus musculus fragment tru-016), dimer …
Matched Description: … Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ceftriaxone
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... its long half-life which allows for the convenience of daily or twice-daily dosing. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Ceftriaxone and Dextrose ... CYROSEF POWDER FOR SOLUTION FOR INJECTION 2GM ... CYROSEF POWDER FOR SOLUTION FOR INJECTION 1GM …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Ceftriaxone and Dextrose ... CYROSEF POWDER FOR SOLUTION FOR INJECTION 2GM ... CYROSEF POWDER FOR SOLUTION FOR INJECTION 1GM …
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Cefuroxime and Dextrose ... Cefuroxime Axetil For Oral Suspension ... Cefuroxime for Injection USP …
Matched Categories: … cefuroxime and metronidazole ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Cefuroxime and Dextrose ... Cefuroxime Axetil For Oral Suspension ... Cefuroxime for Injection USP …
Phenyl hydrogen sulfate
Experimental
Matched Synonyms: … Phenol sulfate …
Matched Name: … Phenyl hydrogen sulfate …
Matched Name: … Phenyl hydrogen sulfate …
ABX-002
Investigational
Matched Synonyms: … 2-(3,5-DICHLORO-4-((4-HYDROXY-3-(PROPAN-2-YL)PHENYL)METHYL)PHENOXY)-N-METHYLACETAMIDE …
Matched Iupac: … 2-(3,5-dichloro-4-{[4-hydroxy-3-(propan-2-yl)phenyl]methyl}phenoxy)-N-methylacetamide …
Matched Iupac: … 2-(3,5-dichloro-4-{[4-hydroxy-3-(propan-2-yl)phenyl]methyl}phenoxy)-N-methylacetamide …
(S)-famoxadone
Experimental
Matched Synonyms: … (S)-5-Methyl-5-(4-phenoxy-phenyl)-3-phenylamino-oxazolidine-2,4-dione …
Sorafenib
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea ... 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Description: … [A255852] First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular ... Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... in tumour cell proliferation and tumour angiogenesis. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Description: … [A255852] First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular ... Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... in tumour cell proliferation and tumour angiogenesis. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Open Form of 2'-Deoxy-Ribofuranose-5'-Phosphate
Experimental
Matched Name: … Open Form of 2'-Deoxy-Ribofuranose-5'-Phosphate …
Oxitriptan
5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in the United Kingdom, United States and Canada as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, and...
Approved
Investigational
Nutraceutical
Matched Synonyms: … 5-hydroxytryptophan L-form …
Matched Description: … metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in ... suppressant, and sleep aid, and is also marketed in many European countries for the indication of major ... the United Kingdom, United States and Canada as a dietary supplement for use as an antidepressant, appetite …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in ... suppressant, and sleep aid, and is also marketed in many European countries for the indication of major ... the United Kingdom, United States and Canada as a dietary supplement for use as an antidepressant, appetite …
Matched Categories: … Amino Acids, Peptides, and Proteins …
NAP-226-90
Experimental
Matched Synonyms: … 3-((1S)-1-(Dimethylamino)ethyl)phenol ... (-)-3-((1S)-1-(Dimethylamino)ethyl)phenol …
Matched Iupac: … 3-[(1S)-1-(dimethylamino)ethyl]phenol …
Matched Iupac: … 3-[(1S)-1-(dimethylamino)ethyl]phenol …
Monobenzone
Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. It exerts a depigmenting effect on skin of mammals by increasing the excretion of melanin from the melanocytes. It may also cause...
Approved
Matched Synonyms: … 4-(Benzyloxy)phenol ... 4-Benzyloxy-phenol ... 4-(Benzyloxyl)phenol …
Matched Iupac: … 4-(benzyloxy)phenol …
Matched Description: … It may also cause destruction of melanocytes and permanent depigmentation. ... Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically ... Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. …
Matched Categories: … Phenols ... Melanin Synthesis Inhibitors …
Matched Iupac: … 4-(benzyloxy)phenol …
Matched Description: … It may also cause destruction of melanocytes and permanent depigmentation. ... Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically ... Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. …
Matched Categories: … Phenols ... Melanin Synthesis Inhibitors …
5-(2-Fluoro-5-{(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]-1-propen-1-yl}phenyl)-1,2-oxazole-3-carboxylic acid
Experimental
Matched Synonyms: … 5-{2-fluoro-5-[3-(3-hydroxy-2-methoxycarbonyl-phenoxy)-propenyl]-phenyl}-isoxazole-3-carboxylic acid …
Matched Name: … 5-(2-Fluoro-5-{(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]-1-propen-1-yl}phenyl)-1,2-oxazole-3-carboxylic …
Matched Iupac: … 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]prop-1-en-1-yl]phenyl}-1,2-oxazole-3-carboxylic …
Matched Name: … 5-(2-Fluoro-5-{(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]-1-propen-1-yl}phenyl)-1,2-oxazole-3-carboxylic …
Matched Iupac: … 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]prop-1-en-1-yl]phenyl}-1,2-oxazole-3-carboxylic …
Phenobarbital
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Synonyms: … 5-Phenyl-5-ethylbarbituric acid ... 5-Ethyl-5-phenyl-pyrimidine-2,4,6-trione ... 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione …
Matched Description: … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... NORAL F FORTE SUPPOZİTUVAR 10 ADET …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … PHENTAL 100 …
Matched Iupac: … 5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione …
Matched Description: … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... NORAL F FORTE SUPPOZİTUVAR 10 ADET …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … PHENTAL 100 …
Valoctocogene roxaparvovec
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 5 vector BMN 270 human blood-coagulation factor VIII SQ variant-specifying …
Matched Description: … [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for ... hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and ... A252797] As opposed to these therapies, valoctocogene roxaparvovec offers the advantage of continuous and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Cellular and Gene Therapy …
Matched Description: … [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for ... hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and ... A252797] As opposed to these therapies, valoctocogene roxaparvovec offers the advantage of continuous and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Cellular and Gene Therapy …
Terpin hydrate
Terpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting with acute or chronic bronchitis, and related pulmonary conditions. It is derived from sources such as turpentine, oregano, thyme and eucalyptus. It was popular in the United States since the late nineteenth century, but...
Approved
Experimental
Matched Synonyms: … Terpin cis-form hydrate …
Matched Description: … with acute or chronic bronchitis, and related pulmonary conditions. ... It is derived from sources such as turpentine, oregano, thyme and eucalyptus. ... Terpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting …
Matched Description: … with acute or chronic bronchitis, and related pulmonary conditions. ... It is derived from sources such as turpentine, oregano, thyme and eucalyptus. ... Terpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting …
Olvimulogene nanivacirepvec
Olvimulogene nanivacirepvec is under investigation in clinical trial NCT01443260 (A Study of GL-ONC1, an Oncolytic Vaccinia Virus, in Patients With Advanced Peritoneal Carcinomatosis).
Investigational
Matched Synonyms: … DNA (synthetic vaccinia virus oncolytic-strain GLV-1h68 (complete genome)) …
Elafibranor
Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).
Approved
Investigational
Matched Synonyms: … PROPANOIC ACID, 2-(2,6-DIMETHYL-4-((1E)-3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)- ... PROPANOIC ACID, 2-(2,6-DIMETHYL-4-(3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)-2-METHYL- …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid …
Matched Description: … Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. ... [A263833] On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid …
Matched Description: … Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. ... [A263833] On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy …
NADH
NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by...
Approved
Nutraceutical
Matched Synonyms: … NAD reduced form …
Matched Description: … NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide ... electron carrier by being alternately oxidized (NAD+) and reduced (NADH). ... It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide ... electron carrier by being alternately oxidized (NAD+) and reduced (NADH). ... It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Phenyl aminosalicylate
Approved
Matched Synonyms: … Phenyl PAS ... Phenyl aminosalicylate ... Phenyl 4-aminosalicylate …
Matched Name: … Phenyl aminosalicylate …
Matched Iupac: … phenyl 4-amino-2-hydroxybenzoate …
Matched Categories: … Phenols …
Matched Name: … Phenyl aminosalicylate …
Matched Iupac: … phenyl 4-amino-2-hydroxybenzoate …
Matched Categories: … Phenols …
Dalteparin
Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000....
Approved
Matched Description: … composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and ... LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … FRAGMIN P FORTE ... FRAGMIN P FOR 5000 IE ... FRAGMIN 5000IE P FORTE …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … FRAGMIN P FORTE ... FRAGMIN P FOR 5000 IE ... FRAGMIN 5000IE P FORTE …
L-3972-T
L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … Human Papilloma Virus (HPV) Type 16 E6/E7 Synthetic Long Peptide (SLP) Vaccine Component L-3972-T …
Matched Description: … L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
Matched Description: … L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …
TW-37
TW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.
Investigational
Matched Synonyms: … phenyl)methyl)- ... N-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl ... N-[4-[[2-(1,1-Dimethylethyl)phenyl]sulfonyl]phenyl]-2,3,4-trihydroxy-5-[[2-(1-methylethyl)phenyl]methyl …
Matched Iupac: … N-[4-(2-tert-butylbenzenesulfonyl)phenyl]-2,3,4-trihydroxy-5-{[2-(propan-2-yl)phenyl]methyl}benzamide …
Matched Description: … TW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.[A253157] …
Matched Iupac: … N-[4-(2-tert-butylbenzenesulfonyl)phenyl]-2,3,4-trihydroxy-5-{[2-(propan-2-yl)phenyl]methyl}benzamide …
Matched Description: … TW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.[A253157] …
Displaying drugs 451 - 475 of 1919 in total