This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Phenyl aminosalicylate
- DrugBank Accession Number
- DB06807
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved
- Structure
Structure for Phenyl aminosalicylate (DB06807)
- Weight
- Average: 229.235
Monoisotopic: 229.073893218 - Chemical Formula
- C13H11NO3
- Synonyms
- Fenamisal
- Fenamisalum
- p-Aminosalol
- Phenyl 4-aminosalicylate
- Phenyl aminosalicylate
- Phenyl PAS
- External IDs
- NSC-40144
Pharmacology
- Indication
Not Available
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAbciximab The risk or severity of bleeding can be increased when Phenyl aminosalicylate is combined with Abciximab. Acarbose Phenyl aminosalicylate may increase the hypoglycemic activities of Acarbose. Aceclofenac The therapeutic efficacy of Phenyl aminosalicylate can be decreased when used in combination with Aceclofenac. Acenocoumarol Phenyl aminosalicylate may increase the anticoagulant activities of Acenocoumarol. Acetaminophen The risk or severity of adverse effects can be increased when Acetaminophen is combined with Phenyl aminosalicylate. Acetazolamide The risk or severity of adverse effects can be increased when Phenyl aminosalicylate is combined with Acetazolamide. Acetohexamide Phenyl aminosalicylate may increase the hypoglycemic activities of Acetohexamide. Acetyldigitoxin The serum concentration of Acetyldigitoxin can be decreased when it is combined with Phenyl aminosalicylate. Acetylsalicylic acid The therapeutic efficacy of Phenyl aminosalicylate can be decreased when used in combination with Acetylsalicylic acid. Albiglutide Phenyl aminosalicylate may increase the hypoglycemic activities of Albiglutide. 
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- Not Available
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as depsides and depsidones. These are polycyclic compounds that is either a polyphenolic compound composed of two or more monocyclic aromatic units linked by an ester bond (depside), or a compound containing the depsidone structure (depsidone).
- Kingdom
- Organic compounds
- Super Class
- Phenylpropanoids and polyketides
- Class
- Depsides and depsidones
- Sub Class
- Not Available
- Direct Parent
- Depsides and depsidones
- Alternative Parents
- o-Hydroxybenzoic acid esters / Aminosalicylic acids and derivatives / Aminobenzoic acids and derivatives / Phenol esters / Phenoxy compounds / Benzoyl derivatives / Aniline and substituted anilines / m-Aminophenols / 1-hydroxy-4-unsubstituted benzenoids / 1-hydroxy-2-unsubstituted benzenoids show 9 more
- Substituents
- 1-hydroxy-2-unsubstituted benzenoid / 1-hydroxy-4-unsubstituted benzenoid / Amine / Amino acid or derivatives / Aminobenzoic acid or derivatives / Aminophenol / Aminosalicylic acid or derivatives / Aniline or substituted anilines / Aromatic homomonocyclic compound / Benzenoid show 23 more
- Molecular Framework
- Aromatic homomonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 52936SIP7V
- CAS number
- 133-11-9
- InChI Key
- DNVVZWSVACQWJE-UHFFFAOYSA-N
- InChI
- InChI=1S/C13H11NO3/c14-9-6-7-11(12(15)8-9)13(16)17-10-4-2-1-3-5-10/h1-8,15H,14H2
- IUPAC Name
- phenyl 4-amino-2-hydroxybenzoate
- SMILES
- NC1=CC(O)=C(C=C1)C(=O)OC1=CC=CC=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 8290
- ChEBI
- 114203
- ChEMBL
- CHEMBL1200868
- ZINC
- ZINC000000119905
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.173 mg/mL ALOGPS logP 3.03 ALOGPS logP 3.15 Chemaxon logS -3.1 ALOGPS pKa (Strongest Acidic) 9.87 Chemaxon pKa (Strongest Basic) 2.32 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 72.55 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 64.54 m3·mol-1 Chemaxon Polarizability 23.52 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created at September 14, 2010 16:21 / Updated at February 21, 2021 18:52