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Displaying drugs 451 - 475 of 1133 in total
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
Approved
Matched Synonyms: … α-methyl-p-tyrosine ... (–)-α-methyl-L-tyrosine ... α-methyl-L-p-tyrosine
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tyrosine Hydroxylase Inhibitors …
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss ... [A263071] Chemically, it consists of 2 heavy and 2 light chains, with each light chain consisting of ... 215 amino acids and each heavy chain consisting of 448 amino acids with 4 intramolecular disulfides. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Prolia ... PROLIA ... PROLIA® …
Experimental
Matched Synonyms: … Phenylalanine amide ... L-phenylalanine amide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … Methionine Phosphonate …
Experimental
Matched Name: … D-Threonine
An essential amino acid. It is often added to animal feed. [PubChem]
Experimental
Matched Synonyms: … D-Lysin
Matched Name: … D-Lysine
The phosphoric acid ester of serine.
Experimental
Matched Synonyms: … Serine phosphate …
Matched Description: … The phosphoric acid ester of serine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Soybean allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Increased Histamine Release …
Matched Products: … Food - Plant Source, Soybean Glycine soja …
Phosphatidyl serine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein kinase C (PKC) which has been shown to be involved in memory function. In apoptosis, phosphatidyl serine is transferred to...
Investigational
Nutraceutical
Matched Synonyms: … Phosphatidyl serine
Matched Name: … Phosphatidyl serine
Matched Description: … Phosphatidyl serine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and ... rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein kinase ... PS has been investigated in a small number of double-blind placebo trials and has been shown to increase …
Experimental
Matched Name: … Magnesium aspartate hydrochloride
Matched Iupac: … magnesium(2+) (2S)-2-aminobutanedioate hydrochloride
Matched Salts name: … Magnesium aspartate hydrochloride trihydrate …
Experimental
Matched Name: … 2-Hydroxy-Tryptophan
Camoteskimab is under investigation in clinical trial NCT06436183 (A Study of the Effects of Camoteskimab in Adults With Moderate to Severe Atopic Dermatitis).
Investigational
Matched Synonyms: … Immunoglobulin g1 (242-phenylalanine,243-glutamic acid,339-serine), anti-(human interleukin 18) (human …
Investigational
Matched Synonyms: … L-valine, l-tyrosyl-l-isoleucyl-l-seryl-l-prolyl-l-tryptophyl-l-isoleucyl-l-leucyl-l-alanyl- …
Experimental
Matched Name: … Furoyl-Leucine
Approved
Experimental
Investigational
Matched Name: … D-Methionine
Experimental
Matched Name: … Imino-Tryptophan
Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in the standard genetic code as the codon UGG. The D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan). The distinguishing...
Experimental
Matched Synonyms: … (R)-tryptophan
Matched Name: … D-Tryptophan
Matched Description: … Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet ... The distinguishing structural characteristic of tryptophan is that it contains an indole functional group …
The D-enantiomer of alanine.
Experimental
Matched Synonyms: … D-Alanin ... (R)-alanine ... D-α-alanine
Matched Name: … D-Alanine
Matched Description: … The D-enantiomer of alanine. …
Experimental
Matched Synonyms: … Glycine amide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.
Experimental
Matched Synonyms: … Formyl-methionine ... N-formyl-L-methionine
Matched Description: … This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic ... The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … -methyl-l-tryptophan C-11 ... L-tryptophan, .alpha.-(methyl-11c)- …
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Synonyms: … 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine ... O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine ... O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
Matched Description: … produce sufficient quantities of the thyroid hormones T4 (tetraiodothyronine or thyroxine) and ... hypothyroidism begin to develop such as fatigue, increased heart rate, depression[A179620], dry skin and ... hair, muscle cramps, constipation, weight gain, memory impairment, and poor tolerance to cold temperatures …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... levothyroxine sodium and iodine compounds …
Pegargiminase is an anticancer agent.
Investigational
Matched Synonyms: … Arginine deiminase pegylated ... Pegylated arginine deiminase …
Matched Categories: … Enzymes and Coenzymes …
An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)
Experimental
Investigational
Matched Synonyms: … Ngamma-Nitro-L-arginine ... N(gamma)-nitro-L-arginine
Matched Description: … alterations in brain energy and ammonia metabolites. ... Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Arginine
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. [PubChem]
Approved
Experimental
Matched Name: … D-Serine
Matched Description: … It is synthesized from GLYCINE or THREONINE. ... It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. [PubChem] …
Displaying drugs 451 - 475 of 1133 in total