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Displaying drugs 451 - 475 of 707 in total
Experimental
Matched Synonyms: … 4-O-β-D-mannopyranosyl-β-D-mannopyranose …
Matched Iupac: … (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5S,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy
Experimental
Matched Synonyms: … 6-O-phosphono-β-D-galactopyranose …
Experimental
Matched Synonyms: … 1,4:3,6-Dianhydro-2,5-bis-O-(3-carbamimidoylphenyl)-D-glucitol …
Matched Name: … 2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol …
Matched Iupac: … 3-{[(3R,3aR,6S,6aR)-6-(3-carbamimidoylphenoxy)-hexahydrofuro[3,2-b]furan-3-yl]oxy}benzene-1-carboximidamide …
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Iupac: … (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with phentermine for chronic weight management therapy...
Approved
Matched Synonyms: … 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate ... 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate …
Matched Description: … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. ... topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and ... 40% of its mass accounted for by oxygen. …
Matched Categories: … Alimentary Tract and Metabolism ... phentermine and topiramate …
Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants With Advanced Parkinson's Disease).
Approved
Investigational
Matched Synonyms: … 3-hydroxy-O-phosphono-L-tyrosine …
Matched Description: … Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and ... Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants …
Matched Categories: … Dopa and Dopa Derivatives ... foslevodopa and decarboxylase inhibitor …
Experimental
Matched Name: … 5'-O-(L-Prolylsulfamoyl)adenosine …
Experimental
Matched Name: … N,O-didansyl-L-tyrosine …
Matched Iupac: … (2S)-3-[4-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}oxy)phenyl]-2-[5-(dimethylamino)naphthalene-1- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … 1-Hexadecanosulfonyl-O-L-Serine …
Matched Iupac: … (2S)-2-amino-3-[(hexadecane-1-sulfonyl)oxy]propanoic acid …
Experimental
Matched Name: … 5'-O-(L-Serylsulfamoyl)adenosine …
Matched Iupac: … 4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-hydroxypropan-1-one
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Experimental
Matched Synonyms: … O-sialic acid …
Matched Description: … An N-acyl derivative of neuraminic acid. ... N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and
Phenylmercuric acetate is an organomercurial compound used as a fungicide and slimicide.
Investigational
Matched Synonyms: … Mercury, (acetato-o)phenyl- …
Matched Description: … Phenylmercuric acetate is an organomercurial compound used as a fungicide and slimicide.[A253082] …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been...
Approved
Matched Synonyms: … o-Salicylsalicylic acid ... O-Salicylcylsalicylsäure …
Matched Description: … synthesis and release of prostaglandins. ... Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of ... A significant portion of the parent compound is absorbed unchanged and undergoes rapid esterase hydrolysis …
Matched Categories: … Salicylic Acid and Derivatives …
Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal dietary supplements . Most commonly, it is an active ingredient in skincare and cosmetic products...
Approved
Matched Synonyms: … hydroquinone O-β-D-glucopyranoside ... Hydroquinone-O-beta-D-glucopyranoside …
Matched Description: … Extracted from the dried leaves of bearberry plant in the genus _Arctostaphylos_ and other plants commonly ... Arbutin is a competitive inhibitor of tyrosinase (E.C.1.14.18.1) in melanocytes [A27248], and the inhibition ... and [DB09526] [F43]. …
Matched Mixtures name: … D-one By Tamdoan Bb Light ... D-one By Tamdoan Bb Medium ... D-one By Tamdoan Sunscreen 50 …
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Description: … conditions of the premature newborn, pain relief, and to combat drowsiness. ... development and may eventually cause asthma or early onset emphysema in those born prematurely. ... [T716] Caffeine is also used in a variety of cosmetic products and can be administered topically, orally …
Matched Mixtures name: … EMOL OSK ... Midol One ... OKA GALEZ …
Matched Categories: … combinations of xanthines ... caffeine and sodium benzoate ... Caffeine and Caffeine Containing Products ... Respiratory and CNS Stimulants ... Anorexigenic Agents & Respiratory and CNS Stimulants …
Matched Products: … Caffeine and Sodium Benzoate …
Experimental
Matched Name: … Sulfamic Acid 2,3-O-(1-Methylethylidene)-4,5-O-Sulfonyl-Beta-Fructopyranose Ester …
A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Description: … It is indicated for infiltration, nerve block, and epidural anesthesia. ... Mepivacaine is effective topically only in large doses and therefore should not be used by this route …
Matched Mixtures name: … Mepivacaine Hydrochloride and Levonordefrin …
Matched Products: … O. MEPIVACAINE 3% PLAIN. SOLUCION INYECTYABLE …
Experimental
Matched Synonyms: … 2'-O-phosphoguanosine …
Matched Iupac: … {[(2R,3R,4R,5R)-2-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … 2,3-Di-O-phytanyl-sn-glycerol …
Matched Name: … 2,3-di-O-phytanyl-sn-glycerol …
Matched Iupac: … (2R)-2,3-bis({[(3R,7R,11R)-3,7,11,15-tetramethylhexadecyl]oxy})propan-1-ol
Experimental
Matched Synonyms: … 5-O-phosphono-β-D-arabinofuranose …
Approved
Vet approved
Matched Synonyms: … 21-O-acetylcortisol …
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … Proctosone Ont ... Ophthocort Ont ... Sopamycetin/hc Ont
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid ... Rectocort Ont ... Cortamed Ont 25 mg/g …
Investigational
Matched Synonyms: … 3-o-(2-acetamido-2-deoxy-.alpha.-d-galactopyranosyl)-2-o-(.alpha.-l-fucopyranosyl)-d-galactose …
Matched Iupac: … 3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}hexan-3-yl]oxy}oxan-3-yl]acetamide ... N-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(2R,3S,4S,5R)-4,5,6-trihydroxy-1-oxo-2-{[(2S, …
Experimental
Matched Synonyms: … 6-O-phosphono-α-D-glucopyranose …
Hesperidin is a flavan-on glycoside found in citrus fruits.
Approved
Investigational
Matched Synonyms: … Hesperetin 7-O-rutinoside …
Matched Iupac: … }methyl)oxan-2-yl]oxy}-3,4-dihydro-2H-1-benzopyran-4-one ... methoxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy
Matched Description: … Hesperidin is a flavan-on glycoside found in citrus fruits. …
Matched Mixtures name: … VENAFIX (Diosmin and Hesperidin Tablet) …
Investigational
Matched Synonyms: … D-streptamine, o-5-amino-5,6-dideoxy-.beta. ... -d-allofuranosyl-(1->5)-o-(2-amino-2,7-dideoxy-d-glycero-.alpha. ... 6'-(r)-methyl-5-o-(5-amino-5,6-dideoxy-a-l-talofuranosyl)- paromamine sulfate …
Matched Iupac: … }-3-hydroxycyclohexyl]oxy}-2-[(1R)-1-hydroxyethyl]oxane-3,4-diol; sulfuric acid ... amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-5-[(1S)-1-aminoethyl]-3,4-dihydroxyoxolan-2-yl]oxy
Displaying drugs 451 - 475 of 707 in total