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Displaying drugs 4751 - 4775 of 7886 in total

Thionicotinamide-Adenine-Dinucleotide

Experimental
Matched Iupac: … {1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}( …

Coenzyme A persulfide

Coenzyme A persulfide is a possible in vivo inhibitor of mammalian short chain acyl-CoA dehydrogenase.
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-({2-[(2-disulfanylethyl)carbamoyl]ethyl}carbamoyl ... )-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan …

EM-1745

Experimental
Matched Iupac: … [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl 9-[(1S,2S,3aS,3bR,9bS,11aS)- …

PI-103

PI-103 is an inhibitor of p110α of class I PI3K.
Investigational
Matched Synonyms: … Phenol, 3-(4-(4-morpholinyl)pyrido(3',2':4,5)furo(3,2-d)pyrimidin-2-yl)- …
Matched Iupac: … 3-[6-(morpholin-4-yl)-8-oxa-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2,4,6,9,11-hexaen-4-yl] …

N-[4-(4-nitrophenylphospho)butanoyl]-L-alanine

Experimental
Matched Synonyms: … N-[4-(4-nitrophenylphospho)butyryl]-L-alanine …
Matched Name: … N-[4-(4-nitrophenylphospho)butanoyl]-L-alanine …
Matched Iupac: … (2S)-2-{4-[hydroxy(4-nitrophenoxy)phosphoryl]butanamido}propanoic acid …

Cevidoplenib

Investigational
Matched Synonyms: … Methanone, cyclopropyl(5-((4-(4-(((4s)-4-hydroxy-2-isoxazolidinyl)methyl)-3-methyl-1h-pyrazol-1-yl)-2 …
Matched Iupac: … -4-yl)methyl]-1,2-oxazolidin-4-ol ... (4S)-2-[(1-{2-[(3-cyclopropanecarbonyl-1-methyl-1H-indol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1H-pyrazol …

NSI-189

NSI-189 is under investigation in clinical trial NCT02695472 (Study of NSI-189 for Major Depressive Disorder).
Investigational
Matched Iupac: … 3-(4-benzylpiperazine-1-carbonyl)-N-(3-methylbutyl)pyridin-2-amine …
Matched Salts cas: … 1270138-41-4 …

Aspartyl-Adenosine-5'-Monophosphate

Experimental
Matched Iupac: … (3S)-3-amino-4-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy) ... phosphoryl)oxy]-4-oxobutanoic acid …

4-Methylimidazole

Experimental
Matched Synonyms: … 4-MEI ... 4(5)-methylimidazole …
Matched Name: … 4-Methylimidazole …
Matched Iupac: … 4-methyl-1H-imidazole …

Elvucitabine

Investigational
Matched Iupac: … 4-amino-5-fluoro-1-[(2S,5R)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-1,2-dihydropyrimidin-2-one …

NM-702

Nissan Chemical and Taisho have been jointly developing NM-702, a drug for the treatment of arteriosclerosis obliterans. M-702 is an orally active inhibitor of phosphodiesterase and thromboxane synthetase. In Japan, Phase 2 studies are being conducted for intermittent claudication caused by arteriosclerosis obliterans, intermittent claudication caused by spinal canal stenosis,...
Investigational
Matched Description: … It is estimated that about 6 million people suffer from intermittent claudication in the USA, with only …

Camphane

Experimental

Bisphenol A

Experimental
Matched Iupac: … 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol …

Cerulenin

Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental

Metavert

Investigational
Matched Synonyms: … Benzamide, n-hydroxy-4-(5-((4-methoxyphenyl)amino)-1,3,4-oxadiazol-2-yl)- ... N-hydroxy-4-(5-((4-methoxyphenyl)amino)-1,3,4-oxadiazol-2-yl)benzamide …
Matched Iupac: … N-hydroxy-4-{5-[(4-methoxyphenyl)amino]-1,3,4-oxadiazol-2-yl}benzamide …

Rezatapopt

Rezatapopt is under investigation in clinical trial NCT04585750 (The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)).
Investigational
Matched Synonyms: … 4-[[3-[4-[[(3S,4R)-3-Fluoro-1-methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn ... Benzamide, 4-[[3-[4-[[(3S,4R)-3-fluoro-1-methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol …

Elzasonan

Elzasonan is under investigation in clinical trial NCT00275197 (A Research Study to Compare the Treatments of a Combination of Elzasonan With Zoloft, to Zoloft Alone, or Placebo in People With Major Depressive Disorder (MDD)).
Investigational
Matched Synonyms: … (2z)-4-(3,4-dichlorphenyl)-2-(2-(4-methylpiperazin-1-yl)benzylidene)thiomorpholin-3-one ... 3-thiomorpholinone, 4-(3,4-dichlorphenyl)-2-((2-(4-methyl-1-piperazinyl) phenyl)methylene)-, (2z)- …

5-(4-Methoxyphenoxy)-2,4-Quinazolinediamine

Experimental
Matched Name: … 5-(4-Methoxyphenoxy)-2,4-Quinazolinediamine …
Matched Iupac: … 5-(4-methoxyphenoxy)quinazoline-2,4-diamine …

4-Androstenediol

Experimental
Illicit
Matched Name: … 4-Androstenediol …

4-Oxosebacic Acid

Experimental
Matched Name: … 4-Oxosebacic Acid …
Matched Iupac: … 4-oxodecanedioic acid …

4-Deoxyglucarate

Experimental
Matched Name: … 4-Deoxyglucarate …

4-Nitro-Inden-1-One

Experimental
Matched Name: … 4-Nitro-Inden-1-One …
Matched Iupac: … 4-nitro-1H-inden-1-one …

4-Methylcoumarin

Experimental
Matched Synonyms: … 4-Methyl-2H-1-benzopyran-2-one …
Matched Name: … 4-Methylcoumarin …
Matched Iupac: … 4-methyl-2H-chromen-2-one …

Tyrphostin B44

Experimental

SAR445136

SAR445136 is an investigational zinc finger nuclease gene-edited cell therapy. It consists of autologous CD34+ hematopoietic stem precursor cells (HSPC) modified ex vivo by zinc finger nucleases (ZFN) that target the BCL11A gene erythroid-specific enhancer (ESE) to increase endogenous HbF production in erythrocytes (RBC). It was formerly investigated for the...
Investigational
Displaying drugs 4751 - 4775 of 7886 in total