Did you mean 10 5r 2?
Displaying drugs 476 - 500 of 13071 in total
Sitaxentan
Sitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension (PAH) by Encysive Pharmaceuticals until Pfizer purchased Encysive in February 2008. In 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity.
Approved
Investigational
Withdrawn
Matched Iupac: … N-(4-chloro-3-methyl-1,2-oxazol-5-yl)-2-[2-(6-methyl-2H-1,3-benzodioxol-5-yl)acetyl]thiophene-3-sulfonamide …
Matched Salts cas: … 210421-74-2 …
Matched Salts cas: … 210421-74-2 …
Hydrochlorothiazide
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459]
Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Mixtures name: … CONVERTAL D 100 ... FORTZAAR 100/25MG ... FORTZAAR 100/25MG …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Hydrochlorothiazide 100 Tab …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Hydrochlorothiazide 100 Tab …
Remimazolam
Remimazolam is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation during short (<30 minute) procedures. Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these agents, such as remifentanil, are designed to be metabolically fragile and thus susceptible to rapid...
Approved
Investigational
Matched Iupac: … methyl 3-[(7S)-12-bromo-3-methyl-9-(pyridin-2-yl)-2,5,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14), …
Matched Salts cas: … 1001415-66-2 ... 1425904-79-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 1001415-66-2 ... 1425904-79-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ruxolitinib
Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2, which are tyrosine kinases involved in cytokine signalling and hematopoiesis. Myeloproliferative neoplasms, such as myelofibrosis and polycythemia vera, are often characterized by...
Approved
Matched Products: … JAKAVI 5 MG (TABLETS) ... JAKAVI 5 MG TABLET, 168 TABLET ... JAKAVI 5 MG TABLET, 14 ADET …
Phenylephrine
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Synonyms: … R(-)-Phenylephrine …
Matched Iupac: … 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol …
Matched Mixtures name: … CORSAL 120 MG + 5 MG + 2 MG/5 ML SURUP, 120 ML ... PİRETİKOL PLUS 160 MG/5 ML+1 MG/5 ML+2.5 MG/5 ML PEDİATRİK ŞURUP, 100 ML ... DEFLU 300 MG/5 MG/2 MG TABLET, 20 ADET …
Matched Products: … Green Guard Allergy 2 Relief ... Phenylephrin Aguettant 100 Mikrogramm/ml Injektions-/Infusionslösung ... FENOSED % 10 STERIL GÖZ DAMLASI, 5 ML …
Matched Iupac: … 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol …
Matched Mixtures name: … CORSAL 120 MG + 5 MG + 2 MG/5 ML SURUP, 120 ML ... PİRETİKOL PLUS 160 MG/5 ML+1 MG/5 ML+2.5 MG/5 ML PEDİATRİK ŞURUP, 100 ML ... DEFLU 300 MG/5 MG/2 MG TABLET, 20 ADET …
Matched Products: … Green Guard Allergy 2 Relief ... Phenylephrin Aguettant 100 Mikrogramm/ml Injektions-/Infusionslösung ... FENOSED % 10 STERIL GÖZ DAMLASI, 5 ML …
Acetohexamide
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Oxygen
Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Products: … Oxygen 100% ... Medical Oxygen 100% ... Oxygen/Nitrogen 5/95 …
Gadoversetamide
Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Approved
Investigational
Matched Iupac: … gadolinium(3+) 2-[bis({2-[(carboxylatomethyl)({[(2-methoxyethyl)carbamoyl]methyl})amino]ethyl})amino] …
Matched Products: … CIPROFLOXACINA 100 MG / 10 ML …
Matched Products: … CIPROFLOXACINA 100 MG / 10 ML …
Azatadine
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaene …
Tavaborole
Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis...
Approved
Investigational
Matched Synonyms: … 5-Fluoro-2,1-benzoxaborol-1(3H)-ol ... 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole …
Matched Iupac: … 5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol …
Matched Iupac: … 5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol …
Polyethylene glycol
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … [A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water …
Matched Mixtures name: … PCP 100 Kit …
Matched Products: … BET-R-Prep …
Matched Mixtures name: … PCP 100 Kit …
Matched Products: … BET-R-Prep …
Bioallethrin
Bioallethrin refers to a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an approximate ratio of 1:1, where both isomers are active ingredients. A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin. A mixture containing only S-forms...
Approved
Experimental
Matched Iupac: … 2-methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane …
Rhodotorula rubra
Rhodotorula rubra is a fungus which can provoke allergic reactions. Rhodotorula rubra is used in allergenic testing.
Approved
Vespula vulgaris venom protein
Vespula vulgaris venom protein is an extract of Vespula vulgaris venom. Vespula vulgaris venom protein is used in allergenic testing.
Approved
Matched Products: … ALUTARD SQ Wespengift Injektionssuspension (Anfangsbehandlung) (100 SQ E/ml, 1.000 SQ E/ml, 10.000 SQ …
Riluzole
A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Iupac: … 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … TEGLUTIK® SUSPENSIÓN ORAL 5 MG/ML ... Teglutik 5 mg/ml Suspension zum Einnehmen ... TEGLUTIK 5 MG/ ML ORAL SÜSPANSIYON, 300 ML …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … TEGLUTIK® SUSPENSIÓN ORAL 5 MG/ML ... Teglutik 5 mg/ml Suspension zum Einnehmen ... TEGLUTIK 5 MG/ ML ORAL SÜSPANSIYON, 300 ML …
Treprostinil
Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Iupac: … 5-yl]oxy}acetic acid ... 2-{[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H,2H,3H,3aH,4H,9H,9aH-cyclopenta[b]naphthalen- …
Matched Description: … However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room …
Matched Products: … TREPOKS 100 MG/20 ML İNFÜZYONLUK ÇÖZELTİ , 1 ADET ... REMODULIN 5 mg/ml Infusionslösung ... Treposa 5 mg/ml Infusionslösung …
Matched Description: … However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room …
Matched Products: … TREPOKS 100 MG/20 ML İNFÜZYONLUK ÇÖZELTİ , 1 ADET ... REMODULIN 5 mg/ml Infusionslösung ... Treposa 5 mg/ml Infusionslösung …
Felodipine
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Synonyms: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Mixtures name: … DELMUNO 5/5 MG ... TRIAPIN 5/5MG ... DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADET …
Matched Products: … ฟีโลปีน 5 ... MODIP 5 MG ... FEDIL SR TABLETS 5 MG …
Matched Iupac: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Mixtures name: … DELMUNO 5/5 MG ... TRIAPIN 5/5MG ... DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADET …
Matched Products: … ฟีโลปีน 5 ... MODIP 5 MG ... FEDIL SR TABLETS 5 MG …
Methylergometrine
A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Approved
Matched Iupac: … (4R,7R)-N-[(2S)-1-hydroxybutan-2-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1 …
Matched Products: … UTERJİN 0,2 MG IM AMPUL, 100 ADET …
Matched Products: … UTERJİN 0,2 MG IM AMPUL, 100 ADET …
Setmelanotide
Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. It is an agonist of the melanocortin 4 receptor. Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate. Other...
Approved
Investigational
Matched Iupac: … (4R,7S,10S,13R,16S,19R,22R)-13-benzyl-22-[(2S)-5-[(diaminomethylidene)amino]-2-acetamidopentanamido]- ... 10-{3-[(diaminomethylidene)amino]propyl}-16-[(1H-imidazol-5-yl)methyl]-7-[(1H-indol-3-yl)methyl]-19-methyl …
Rupatadine
Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and...
Approved
Matched Iupac: … 13-chloro-2-{1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene}-4-azatricyclo[9.4.0.0^{3,8}]pentadeca …
Salmeterol
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Iupac: … 4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol …
Matched Description: … Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for ... [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 …
Matched Mixtures name: … SERETIDE 50/100 ACCUHALER 50 mcg/100 mcg ... Advair 100 Diskus ... SERETIDE DISKUS 100 …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Matched Description: … Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for ... [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 …
Matched Mixtures name: … SERETIDE 50/100 ACCUHALER 50 mcg/100 mcg ... Advair 100 Diskus ... SERETIDE DISKUS 100 …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Rimegepant
Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. It received FDA approval on February 27, 2020 for the acute treatment migraine headache, and was subsequently approved by the European Commission in April 2022 for both the treatment and prevention of migraines. While several parenteral antagonists...
Approved
Investigational
Matched Iupac: … (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-9-yl 4-{2-oxo-1H,2H,3H-imidazo …
Matched Salts cas: … 1374024-48-2 …
Matched Salts cas: … 1374024-48-2 …
Taliglucerase alfa
Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase. It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Approved
Investigational
Lopinavir
Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Iupac: … (2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2- ... (2-oxo-1,3-diazinan-1-yl)butanamide …
Matched Description: … under investigation in combination with ritonavir for the treatment of COVID-19 caused by SARS-CoV-2. …
Matched Mixtures name: … LOPIVIA 100/25 ... ALUVIA (100 MG/25 MG) ... KALETRA® 100/25 TABLETAS …
Matched Description: … under investigation in combination with ritonavir for the treatment of COVID-19 caused by SARS-CoV-2. …
Matched Mixtures name: … LOPIVIA 100/25 ... ALUVIA (100 MG/25 MG) ... KALETRA® 100/25 TABLETAS …
Displaying drugs 476 - 500 of 13071 in total