Displaying drugs 476 - 500 of 904 in total
Spermine
Spermine is a spermidine-derived biogenic polyamine found as a polycation at all pH values. Found in various tissues and organisms, it often acts as an essential growth factor in some bacterial species. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
Experimental
Nutraceutical
Matched Synonyms: … N,N'-Bis(3-aminopropyl)-1,4-butanediamine …
Dihematoporphyrin ether
Dihematoporphyrin ether is under investigation in clinical trial NCT00118222 (High Light and Low Light Dose PDT in Glioma).
Investigational
Matched Synonyms: … bis-1-(8-(1-hydroxyethyl)deuteroporphyrin-3-yl)ethyl ether …
Matched Iupac: … 3-[15-(1-{1-[10,14-bis(2-carboxyethyl)-19-(1-hydroxyethyl)-5,9,15,20-tetramethyl-21,22,23,24-tetraazapentacyclo …
Matched Iupac: … 3-[15-(1-{1-[10,14-bis(2-carboxyethyl)-19-(1-hydroxyethyl)-5,9,15,20-tetramethyl-21,22,23,24-tetraazapentacyclo …
OBI-3424
OBI-3424 is under investigation in clinical trial NCT04315324 (Study to Test Akr1c3-activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/refractory T-cell Acute Lymphoblastic Leukemia (T-ALL)).
Investigational
Matched Synonyms: … 3-(5-((1R)-1-(Bis(aziridin-1-yl(phosphoryloxy)ethyl)-2-nitrophenoxy)-N,N-dimethylbenzamide ... 3-[5-[(1R)-1-[bis(aziridin-1-yl(phosphoryloxy]ethyl]-2-nitrophenoxy]-N,N-dimethylbenzamide ... Phosphinic acid, P,P-bis(1-aziridinyl)-, (1R)-1-(3-(3-((dimethylamino)carbonyl)phenoxy)-4-nitrophenyl …
Matched Iupac: … (1R)-1-{3-[3-(dimethylcarbamoyl)phenoxy]-4-nitrophenyl}ethyl bis(aziridin-1-yl)phosphinate …
Matched Iupac: … (1R)-1-{3-[3-(dimethylcarbamoyl)phenoxy]-4-nitrophenyl}ethyl bis(aziridin-1-yl)phosphinate …
LGD-2226
An androgen receptor modulator.
Experimental
Matched Synonyms: … 6-(Bis-(2,2,2-trifluoroethyl)amino)-4-trifluoromethyl-1H-quinolin-2-one …
Matched Iupac: … 6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one …
Matched Iupac: … 6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one …
Ezeprogind
Investigational
Matched Synonyms: … 1,4-piperazinedipropanamine, n'-1h-benzimidazol-2-yl-n,n-bis(2-methylpropyl)- ... 1,4-piperazinedipropanamine, n4-1h-benzimidazol-2-yl-n1,n1-bis(2-methylpropyl)- ... N4-1h-benzimidazol-2-yl-n1,n1-bis(2-methylpropyl)-1,4-piperazinedipropanamine …
Matched Iupac: … N-[3-(4-{3-[bis(2-methylpropyl)amino]propyl}piperazin-1-yl)propyl]-1H-1,3-benzodiazol-2-amine …
Matched Iupac: … N-[3-(4-{3-[bis(2-methylpropyl)amino]propyl}piperazin-1-yl)propyl]-1H-1,3-benzodiazol-2-amine …
Alcuronium
A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
Experimental
Matched Synonyms: … N,N'-diallyl-bis-nor-toxiferine …
Matched Iupac: … (1S,9Z,11S,13S,14R,17S,25Z,27S,28E,30R,33S,35S,37E,38S)-28,37-bis(2-hydroxyethylidene)-14,30-bis(prop …
Matched Iupac: … (1S,9Z,11S,13S,14R,17S,25Z,27S,28E,30R,33S,35S,37E,38S)-28,37-bis(2-hydroxyethylidene)-14,30-bis(prop …
1,3-bis-([[3-(4-{3-[3-nitro-5-(galactopyranosyloxy)-benzoylamino]-propyl}-piperazin-1-yl)-propylamino-3,4-dioxo-cyclobutenyl]-amino-ethyl]-amino-carbonyloxy)-2-amino-propane
Experimental
Matched Name: … 1,3-bis-([[3-(4-{3-[3-nitro-5-(galactopyranosyloxy)-benzoylamino]-propyl}-piperazin-1-yl)-propylamino …
VLX-1570
VLX-1570 is under investigation in clinical trial NCT02372240 (A Study of VLX1570 and Dexamethasone in Myeloma Patients).
Investigational
Matched Synonyms: … (3E,5E)-3,5-Bis[(4-Fluoro-3-Nitrophenyl)Methylidene]-1-(Prop-2-Enoyl)Azepan-4-0Ne …
Matched Iupac: … (3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-one …
Matched Iupac: … (3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-one …
RH-1
RH-1 has been used in trials studying the treatment of Advanced Solid Tumors and Non-Hodgkin's Lymphoma.
Experimental
Investigational
Matched Synonyms: … 2,5-Cyclohexadiene-1,4-dione, 2,5-bis(1-aziridinyl)-3-(hydroxymethyl)-6-methyl- …
Matched Iupac: … 2,5-bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione …
Matched Iupac: … 2,5-bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione …
Diminazene
Diminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide, diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent. Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin. This substance is a solid. This compound belongs to the phenylhydrazines. These are compounds containing a phenylhydrazide moiety, which consists of a hydrazide substituent...
Experimental
Matched Synonyms: … 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide …
Matched Description: … Diminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide …
Matched Description: … Diminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide …
NS-3728
NS3728 is an orally active chloride channel blocker for the treatment of cancer.
Investigational
Matched Synonyms: … N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-N'-[3,5-bis(trifluoromethyl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
Diethylnorspermine
Investigational
Matched Synonyms: … 1,3-PROPANEDIAMINE, N,N'-BIS(3-(ETHYLAMINO)PROPYL)- …
Bambuterol
Bambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.
Investigational
Matched Synonyms: … (±)-5-(2-(tert-butylamino)-1-hydroxyethyl)-m-phenylene bis(dimethylcarbamate) …
Propofol Hemisuccinate
Experimental
Matched Synonyms: … Butanedioic acid, 1-(2,6-bis(1-methylethyl)phenyl) ester …
Matched Iupac: … 4-[2,6-bis(propan-2-yl)phenoxy]-4-oxobutanoic acid …
Matched Iupac: … 4-[2,6-bis(propan-2-yl)phenoxy]-4-oxobutanoic acid …
Tegavivint
Investigational
Matched Synonyms: … 9,10-anthracenedione, 2,7-bis(((3r,5s)-3,5-dimethyl-1-piperidinyl)sulfonyl)-, 9,10-dioxime, rel- …
Matched Iupac: … N-[2,7-bis({[(3R,5S)-3,5-dimethylpiperidin-1-yl]sulfonyl})-10-(hydroxyimino)-9,10-dihydroanthracen-9- …
Matched Iupac: … N-[2,7-bis({[(3R,5S)-3,5-dimethylpiperidin-1-yl]sulfonyl})-10-(hydroxyimino)-9,10-dihydroanthracen-9- …
Docarpamine
Investigational
Matched Synonyms: … (-)-(s)-2-acetamido-n-(3,4-dihydroxyphenethyl)-4-(methylthio)butyramide bis(ethyl carbonate) (ester) …
Olitigaltin
Olitigaltin has been investigated for the treatment of Idiopathic Pulmonary Fibrosis.
Investigational
Matched Synonyms: … Bis-(3-deoxy-3-(4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl)-B-D-galactopyranosyl) sulfane …
Ethyl biscoumacetate
Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)
Withdrawn
Matched Synonyms: … Ethyl bis(4-hydroxy-2-oxo-2h-1-benzopyran-3-yl)acetate …
Matched Iupac: … ethyl 2,2-bis(4-hydroxy-2-oxo-2H-chromen-3-yl)acetate …
Matched Iupac: … ethyl 2,2-bis(4-hydroxy-2-oxo-2H-chromen-3-yl)acetate …
Matairesinol
Experimental
Matched Synonyms: … 3R,4R-Bis((4-hydroxy-3-methoxyphenyl)methyl)dihydro-2(3H)-furanone …
Matched Iupac: … (3R,4R)-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one …
Matched Iupac: … (3R,4R)-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one …
TG100-115
An NSAID that inhibits PI-3K gamma and delta.
Investigational
Matched Synonyms: … 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine …
Vorasidenib
Investigational
Matched Synonyms: … 1,3,5-triazine-2,4-diamine, 6-(6-chloro-2-pyridinyl)-n2,n4-bis((1r)-2,2,2-trifluoro-1-methylethyl)- …
Matched Iupac: … 6-(6-chloropyridin-2-yl)-N2,N4-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine …
Matched Iupac: … 6-(6-chloropyridin-2-yl)-N2,N4-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine …
Technetium TC-99M trofolastat
Investigational
Matched Synonyms: … -glutamyl-n6,n6-bis((1-(2-(bis(carboxymethyl)amino)-2-oxoethyl)-1h-imidazol-2-yl-.kappa.n3)methyl)-l-lysine …
Displaying drugs 476 - 500 of 904 in total