Displaying drugs 476 - 500 of 2733 in total
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. ... homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as human …
Matched Description: … Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. ... homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as human …
Tozinameran
The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of four advanced mRNA-based vaccines developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002,L15007,L36025] Comirnaty is a nucleoside modified mRNA (modRNA) vaccine encoding an optimized full-length version of the severe acute respiratory syndrome coronavirus 2...
Approved
Investigational
Matched Synonyms: … Pfizer-BioNTech COVID-19 Vaccine …
Matched Description: … The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of ... It is designed to induce immunity against SARS-CoV-2, the virus responsible for causing COVID-19. ... Currently, sufficient data are not available to determine the longevity of protection against COVID-19 …
Matched Mixtures name: … Pfizer-BioNTech Covid-19 Vaccine, Bivalent ... Pfizer-BioNTech Covid-19 Vaccine, Bivalent ... Pfizer-BioNTech Covid-19 Vaccine, Bivalent …
Matched Categories: … COVID-19 Vaccines ... Recombinant Proteins …
Matched Products: … Pfizer-BioNTech Covid-19 Vaccine …
Matched Description: … The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of ... It is designed to induce immunity against SARS-CoV-2, the virus responsible for causing COVID-19. ... Currently, sufficient data are not available to determine the longevity of protection against COVID-19 …
Matched Mixtures name: … Pfizer-BioNTech Covid-19 Vaccine, Bivalent ... Pfizer-BioNTech Covid-19 Vaccine, Bivalent ... Pfizer-BioNTech Covid-19 Vaccine, Bivalent …
Matched Categories: … COVID-19 Vaccines ... Recombinant Proteins …
Matched Products: … Pfizer-BioNTech Covid-19 Vaccine …
Mecasermin
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I ... Mecasermin recombinant ... Human somatomedin C …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. ... protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human …
Matched Categories: … Recombinant Human Insulin-like Growth Factor-1 ... Human Insulin-like Growth Factor Analogs …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. ... protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human …
Matched Categories: … Recombinant Human Insulin-like Growth Factor-1 ... Human Insulin-like Growth Factor Analogs …
Eftrenonacog alfa
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Recombinant human coagulation factor IX, FC Fusion protein ... Coagulation factor IX recombinant immunoglubulin g1 fusion protein …
Matched Description: … (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H ... Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. ... It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region …
Matched Categories: … Recombinant Proteins …
Matched Description: … (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H ... Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. ... It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region …
Matched Categories: … Recombinant Proteins …
Insulin detemir
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin,detemir,human ... Insulin detemir recombinant …
Matched Description: … typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] Insulin detemir is produced using recombinant DNA technology in yeast cells …
Matched Description: … typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] Insulin detemir is produced using recombinant DNA technology in yeast cells …
Anakinra
Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues. Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta. Anakinra is...
Approved
Investigational
Matched Synonyms: … Interleukin-1 receptor antagonist anakinra …
Matched Description: … Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino ... Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. ... few studies have evaluated the use of anakinra for the treatment of coronavirus disease 2019 (COVID-19 …
Matched Categories: … Interleukin Inhibitors ... Interleukin-1 Receptor Antagonist …
Matched Description: … Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino ... Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. ... few studies have evaluated the use of anakinra for the treatment of coronavirus disease 2019 (COVID-19 …
Matched Categories: … Interleukin Inhibitors ... Interleukin-1 Receptor Antagonist …
Influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) recombinant hemagglutinin antigen …
Coagulation Factor IX (Recombinant)
Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX recombinant human ... Recombinant factor IX ... Factor IX (Recombinant) …
Matched Name: … Coagulation Factor IX (Recombinant) …
Matched Description: … It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically ... Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, …
Matched Name: … Coagulation Factor IX (Recombinant) …
Matched Description: … It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically ... Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, …
Spesolimab
Spesolimab is an interleukin-36 (IL-36) receptor antagonist. It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. The biosimilar of the drug, spesolimab-sbzo, was first approved by the FDA in September 2022 to treat generalized pustular psoriasis flares. Spesolimab...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain) …
Matched Description: … Spesolimab is an interleukin-36 (IL-36) receptor antagonist. ... humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant ... A252220, A252225] Spesolimab received recommendations from the EMA's Committee for Medicinal Products for Human …
Matched Categories: … Interleukin Inhibitors ... Interleukin-36 Receptor Antagonist …
Matched Description: … Spesolimab is an interleukin-36 (IL-36) receptor antagonist. ... humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant ... A252220, A252225] Spesolimab received recommendations from the EMA's Committee for Medicinal Products for Human …
Matched Categories: … Interleukin Inhibitors ... Interleukin-36 Receptor Antagonist …
Galsulfase
Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Synonyms: … N-acetylgalactosamine-4-sulfatase, recombinant human …
Matched Description: … Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant ... The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation …
Matched Description: … Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant ... The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation …
Nesiritide
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Approved
Investigational
Matched Synonyms: … Nesiritide recombinant ... Human brain natriuretic factor-32 …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Nandrolone decanoate
Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis.[A233789,A233849,L32564,L9464] The process for creating esters of nandrolone was patented in Spain in 1959 and in 1960,...
Approved
Illicit
Matched Synonyms: … 19-nortestosterone decanoate …
Andusomeran
Andusomeran is a COVID-19 mRNA vaccine developed for use during the 2023-2024 season.[L40074,L48832,L48837] It is similar to previous mRNA vaccines developed by Moderna (e.g. elasomeran, imelasomeran), but is designed to be effective against the Omicron XBB.1.5 subvariant.
Approved
Matched Synonyms: … COVID-19 mRNA vaccine, monovalent (XBB.1.5 Variant) …
Matched Description: … Andusomeran is a COVID-19 mRNA vaccine developed for use during the 2023-2024 season. …
Matched Categories: … COVID-19 Vaccines …
Matched Products: … Moderna COVID-19 Vaccine …
Matched Description: … Andusomeran is a COVID-19 mRNA vaccine developed for use during the 2023-2024 season. …
Matched Categories: … COVID-19 Vaccines …
Matched Products: … Moderna COVID-19 Vaccine …
Norethisterone
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Synonyms: … 19-nor-ethindrone ... 19-norethisterone ... 17-α-ethynyl-19-nortestosterone …
Matched Description: … Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19 …
Matched Description: … Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19 …
Paricalcitol
Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Approved
Investigational
Matched Synonyms: … 19-Nor-1alpha,25-dihydroxyvitamin D2 …
Antithrombin Alfa
Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention of thromboembolic events in patients that have hereditary deficiency of antithrombin in high risk situations.
Approved
Investigational
Matched Synonyms: … Antithrombin (recombinant) ... Antithrombin III, recombinant ... Antithrombin III,recombinant …
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Matched Categories: … Recombinant Antithrombin …
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Matched Categories: … Recombinant Antithrombin …
Dibotermin alfa
Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Synonyms: … Bone morphogenetic protein 2 (human recombinant rhBMP-2) …
Matched Description: … Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant …
Matched Description: … Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant …
Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine
The Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada for the prevention of COVID-19. It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with...
Approved
Matched Synonyms: … Recombinant SARS-CoV-2 spike (S)-protein virus-like particle …
Matched Name: … Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine …
Matched Description: … The Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a ... COVID-19 vaccine]) and nucleic acid vaccines (e.g. the [Moderna COVID-19 vaccine]). ... partnership by Medicago and GlaxoSmithKline which is approved in Canada for the prevention of COVID-19 …
Matched Categories: … COVID-19 Vaccines …
Matched Name: … Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine …
Matched Description: … The Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a ... COVID-19 vaccine]) and nucleic acid vaccines (e.g. the [Moderna COVID-19 vaccine]). ... partnership by Medicago and GlaxoSmithKline which is approved in Canada for the prevention of COVID-19 …
Matched Categories: … COVID-19 Vaccines …
Erythropoietin
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Erythropoietin (recombinant human) ... Erythropoietin (human, recombinant) ... Epoetin alfa, recombinant …
Matched Description: … molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human ... Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant …
Matched Description: … molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human ... Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant …
Nomegestrol acetate
Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Approved
Investigational
Matched Synonyms: … 17-alpha-Acetoxy-6-methyl-19-nor-4,6-pregnadiene-3,20-dione ... 17-alpha-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate …
Teduglutide
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Synonyms: … Teduglutide Recombinant ... Glucagon-like peptide II (2-glycine) (human) …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Segesterone acetate
Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 . In animal studies, segesterone acetate was shown to be one of the most potent progestins . It mediates progestational activity 100 times higher than that of progesterone ....
Approved
Experimental
Investigational
Matched Synonyms: … 16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dione ... 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate …
Matched Description: … Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative …
Matched Description: … Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative …
Eptotermin alfa
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Human recombinant bone morphogenetic protein 7 …
Alglucosidase alfa
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the ... Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Matched Description: … Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the ... Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Imlifidase
Chronic kidney disease (CKD) is a progressive and irreversible disease that represents a significant burden for both the individual and healthcare system at large. Currently available treatments for end-stage renal disease are limited to dialysis and renal transplantation, with the former associated with significant costs and lower quality of life.[A225836,A225916]...
Approved
Investigational
Matched Synonyms: … IdeS recombinant …
Matched Description: … [A225836,A225916] Patients who have developed human leukocyte antigen (HLA) sensitization from prior ... and eliminates Fc-dependent effector functions such as CDC and ADCC by cleaving the heavy chains of human …
Matched Description: … [A225836,A225916] Patients who have developed human leukocyte antigen (HLA) sensitization from prior ... and eliminates Fc-dependent effector functions such as CDC and ADCC by cleaving the heavy chains of human …
Displaying drugs 476 - 500 of 2733 in total