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Displaying drugs 5051 - 5075 of 11598 in total
Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) . Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants . Tianeptine was discovered and...
Investigational
Matched Description: … Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied ... Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Investigational
ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a robust and durable...
Investigational
Matched Description: … Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. ... ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon ... human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a
Delorazepam is a benzodiazepine which, like other drugs in its class, possesses anxiolytic, skeletal muscle relaxant, hypnotic and anticonvulsant properties. It may have adverse effects such as drowsiness, and cognitive impairments such as short term memory impairment. Delorazepam is an active metabolite of the benzodiazepine known as cloxazolam. It is...
Experimental
Illicit
Matched Description: … Lorazepam is also a major active metabolite of delorazepam. ... Delorazepam is a benzodiazepine which, like other drugs in its class, possesses anxiolytic, skeletal ... It is a long acting benzodiazepine which makes it superior in this sense to lorazepam which is short …
Chlorpyramine is a first generation antihistamine used in Eastern European countries to treat bronchial asthma as well as allergice rhinitis, allergic conjunctivitis, and other allergic reactions. It is also indicated for Quincke's edema, allergic reactions to insect bites, food and drug allergies, and anaphylactic shock.
Experimental
Matched Description: … Chlorpyramine is a first generation antihistamine used in Eastern European countries to treat bronchial …
Acediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone.
Experimental
Maduramicin is an antiprotozoal agent used in veterinary medicine as prophylaxis against coccidiosis. It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra.
Vet approved
Matched Description: … It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra …
Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.[L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19.
Investigational
Matched Description: … Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Vitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma.
Investigational
Matched Description: … Vitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Vet approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more rapidly than tamoxifen. Its higher affinity to the estrogen receptor, higher anti-estrogenic to estrogenic ratio, more effective inhibition of cell...
Investigational
Matched Description: … Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor ... It may have a particular role in situations in which rapid pharmacokinetics, or an increased antiestrogenic ... Droloxifene may also be a potentially useful agent for the treatment of postmenopausal osteoporosis because …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent in cardiac perfusion imaging studies. It is developed by Bristol-Myers Squibb and is in phase II of clinical trials.
Investigational
Matched Description: … Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent …
Matched Categories: … Adenosine A receptor agonists …
Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations and triggering cell...
Experimental
Matched Description: … Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Methyl-1-testosterone is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use. It is a derivative of 1-testosterone with a methyl group in the carbon 17. Methyl-1-testosterone is considered a prohibited doping substance.
Experimental
Illicit
Matched Iupac: … 11aS)-1-hydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … It is a derivative of 1-testosterone with a methyl group in the carbon 17. ... Methyl-1-testosterone is considered a prohibited doping substance. ... Methyl-1-testosterone is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never …
BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.
Investigational
Matched Iupac: … 1H-indol-3-yl)methyl]-6-(2-methylpropyl)-1,4,7,10,13-pentaoxo-3-(propan-2-yl)-hexadecahydro-1H-pyrrolo[1,2-a] …
Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is an androgen ester – specifically, the C17 acetate ester of DB05830.
Experimental
Matched Iupac: … ,9aR,9bS,11aS)-4,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of …
Illicit
Vet approved
Matched Iupac: … 3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]
Experimental
Vet approved
Matched Description: … An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 5051 - 5075 of 11598 in total