Displaying drugs 5076 - 5100 of 11436 in total
Aptazapine
Aptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. Aptazapine had noradrenergic and specific serotonergic activity. It antagonised α2 adrenergic receptors approximately 10 times more effectively than mianserin, antagonised 5-HT2 receptors, agonised H1 receptors, and did not affect reuptake of serotonin or norepinephrine. Although Aptazapine reached clinical trials, it...
Experimental
Matched Description: … Aptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. …
Acetrizoic acid
Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid and it is the first monomeric ionic compound used as an X-ray contrast agent. It was first synthesized by Wallingford in 1953 and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th,...
Withdrawn
Matched Description: … [L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
UB-612
The UB-612 COVID-19 vaccine was developed by United Biomedical Inc Asia in Taipei as the first COVID-19 “multi-tope” protein-peptide vaccine made up of eight rationally designed components . The vaccine incorporates a strong S1-RBD component linked to a single chain fragment region (sFC) of a human IgG1, which facilitates cell...
Investigational
Matched Description: … The vaccine incorporates a strong S1-RBD component linked to a single chain fragment region (sFC) of ... This vaccine was designed to induce a broad immune response. ... a human IgG1, which facilitates cell attachment and acts as the principal neutralizing domain of the …
Allogeneic natural killer cells
Investigational
Marine collagen, soluble
Marine collagen, soluble is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Avotaciclib
Avotaciclib is under investigation in clinical trial NCT03579836 (Evaluation of Safety and Efficacy in BEY1107 in Monotherapy Gemcitabine Combination in Patient With Pancreatic Cancer).
Investigational
Anise oil
Experimental
Myb34.5
Investigational
Codrituzumab
Codrituzumab is under investigation in clinical trial NCT01507168 (A Study of RO5137382 (GC33) in Patients With Advanced or Metastatic Hepatocellular Carcinoma).
Investigational
Matched Description: … Codrituzumab is under investigation in clinical trial NCT01507168 (A Study of RO5137382 (GC33) in Patients …
Coprelotamab
Coprelotamab is under investigation in clinical trial NCT04170595 (Clinical Study of Recombinant Anti-her2 Humanized Monoclonal Antibody for Injection).
Investigational
Bicuculline
Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.
Experimental
Matched Description: … Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. …
Matched Categories: … GABA-A Receptor Antagonists …
Matched Categories: … GABA-A Receptor Antagonists …
Nefiracetam
Nefiracetam has been used in trials studying the treatment of Alzheimer's Disease.
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ex vivo expanded autologous human corneal epithelial cells containing stem cells
Holoclar (ex vivo expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.
Investigational
Matched Description: … Holoclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem …
HE3286
Investigational
Matched Iupac: … 9bS,11aS)-1-ethynyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Galeterone
Galeterone has been used in trials studying the treatment of Prostate Cancer.
Investigational
Matched Iupac: … (1H-1,3-benzodiazol-1-yl)-9a,11a-dimethyl-3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
(1,2,6,7-3H)Testosterone
Experimental
Matched Iupac: … hydroxy-9a,11a-dimethyl(4,5,8,9-3H4)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Pregnenolone acetate
Investigational
Matched Iupac: … ,9bS,11aS)-1-acetyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Tauroselcholic acid
Experimental
Matched Iupac: … 1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aS)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Prasterone sulfate
DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.
Investigational
Matched Iupac: … 9aR,9bS,11aS)-9a,11a-dimethyl-1-oxo-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Dansylamide
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Paraoxon
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sonlicromanol
Sonlicromanol is under investigation in clinical trial NCT04165239 (The KHENERGYZE Study).
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
MVC-COV1901
MVC-COV1901 is a vaccine candidate developed and commercialized by Medigen Vaccine Biologics Corporation. The vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein. Medigen has combined forces with Dynavax, which offers an advanced adjuvant, CpG 1018 (also known as ISS-1018), for use with its vaccine. As of...
Investigational
Matched Description: … The vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein. ... MVC-COV1901 is a vaccine candidate developed and commercialized by Medigen Vaccine Biologics Corporation …
Cholesterol sulfate
Component of human seminal plasma & spermatozoa.
Experimental
Matched Iupac: … 11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Oxalic Acid
A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent. [PubChem]
Experimental
Matched Description: … A strong dicarboxylic acid occurring in many plants and vegetables. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 5076 - 5100 of 11436 in total