Displaying drugs 501 - 525 of 1064 in total
Bismuth subnitrate
Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent . The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.
Approved
Matched Synonyms: … Bismuth nitrate, basic …
Matched Description: … is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Description: … is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
N-hexadecanoylglycine
Experimental
Matched Synonyms: … N-Palmitoyl glycine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Parathyroid Hormone-Related Protein 1-36
Parathyroid Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and PTH to Treat Osteoporosis).
Investigational
Matched Synonyms: … 1-36 human humoral hypercalcemic factor ... Parathormone-related peptide (1-36) (human) ... 1-36 human parathyroid hormone-related protein …
Matched Description: … Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and …
Matched Categories: … Biological Factors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Hormone-Related Protein 1-36 is under investigation in clinical trial NCT00853723 (Comparison Study of Pthrp and …
Matched Categories: … Biological Factors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
AMGN-0007
Recombinant osteoprotegerin (AMGN-0007) is a recombinant OPG construct developed as a potential therapeutic agent in the treatment of bone disease.
Investigational
Matched Synonyms: … Osteoclastogenesis inhibitory factor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tumor Necrosis Factor Decoy Receptors …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tumor Necrosis Factor Decoy Receptors …
Somatostatin
Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where...
Approved
Investigational
Matched Synonyms: … Synthetic growth hormone release-inhibiting hormone …
Matched Description: … generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating ... It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also ... Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating ... It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also ... Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
GYM329
GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Efmoroctocog alfa
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant, FC fusion protein) ... Antihemophilic Factor (Recombinant BDD), FC Fusion Protein ... Coagulation factor VIII recombinant immunoglubulin g1 fusion protein …
Matched Description: … is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... is produced by recombinant DNA technology and is identical in sequence to endogenously produced Factor ... other hemorrhages that cause chronic pain and disability to patients [A31551, A31552]. …
Matched Categories: … Human Antihemophilic Factors …
Matched Description: … is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... is produced by recombinant DNA technology and is identical in sequence to endogenously produced Factor ... other hemorrhages that cause chronic pain and disability to patients [A31551, A31552]. …
Matched Categories: … Human Antihemophilic Factors …
Secretin human
Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Synonyms: … Human secretin ... Secretin human ... Secretin (human) …
Matched Name: … Secretin human …
Matched Description: … Synthetic human secretin displays equivalent biological activity and properties as naturally-occurring ... , and liver. ... of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification …
Matched Salts name: … Secretin human pentahydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Secretin human …
Matched Description: … Synthetic human secretin displays equivalent biological activity and properties as naturally-occurring ... , and liver. ... of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification …
Matched Salts name: … Secretin human pentahydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Docetaxel
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
Paromomycin
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Approved
Investigational
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Humatin ... HUMATIN ... Humatin - Pulvis …
Matched Products: … Humatin ... HUMATIN ... Humatin - Pulvis …
Susoctocog alfa
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant) porcine sequence ... ANTIHEMOPHILIC FACTOR (RECOMBINANT), PORCINE SEQUENCE ... Porcine recombinant factor VIII B-domain truncated …
Matched Description: … These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this ... The recombinant porcine sequence allows less susceptibility to inactivation by circulating human factor ... Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for …
Matched Categories: … Blood and Blood Forming Organs ... Blood Coagulation Factors …
Matched Description: … These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this ... The recombinant porcine sequence allows less susceptibility to inactivation by circulating human factor ... Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for …
Matched Categories: … Blood and Blood Forming Organs ... Blood Coagulation Factors …
Regramostim
Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of...
Investigational
Matched Synonyms: … Colony-stimulating factor 2 (human clone pCSF-1 protein moiety reduced), glycoform GMC 89-107 …
Matched Description: … Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ ... Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and ... GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their …
Matched Categories: … Hematopoietic Cell Growth Factors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Biological Factors ... Colony-Stimulating Factors …
Matched Description: … Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ ... Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and ... GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their …
Matched Categories: … Hematopoietic Cell Growth Factors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Biological Factors ... Colony-Stimulating Factors …
Acacia
Acacia allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Plants and plant parts, gum, acacia or arabic acacia senegal …
Human calcitonin
Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect. It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. It is used as an alternative for people developing antibodies against salmon calcitonin.
Approved
Investigational
Matched Synonyms: … Calcitonin human ... Calcitonin (human) ... Calcitonin, human …
Matched Name: … Human calcitonin …
Matched Categories: … Sex Hormones and Insulins ... calcitonin (human synthetic) …
Matched Name: … Human calcitonin …
Matched Categories: … Sex Hormones and Insulins ... calcitonin (human synthetic) …
Proinsulin human
Investigational
Matched Synonyms: … Proinsulin human ... Proinsulin biosynthetic human ... Proinsulin recombinant human …
Matched Name: … Proinsulin human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Proinsulin human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Haptoglobulin (human)
Investigational
Matched Synonyms: … Human haptoglobulin …
Matched Name: … Haptoglobulin (human) …
Matched Name: … Haptoglobulin (human) …
Aluminum sulfate
Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group 13 (IIIa, or boron group) of the periodic table .
It is a chemical agent used in water purification, the pH regulation of garden soil, and other commercial or industrial applications. Medically, it is primarily used...
Approved
Matched Description: … , and tap water. ... bone and the central nervous system [L2145]. ... It is a chemical agent used in water purification, the pH regulation of garden soil, and other commercial …
Matched Categories: … Immunologic Factors …
Matched Products: … Shaving Factory Disposable Styptic Pencil …
Matched Categories: … Immunologic Factors …
Matched Products: … Shaving Factory Disposable Styptic Pencil …
Memantine
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … MEMANTIN BASICS 10MG ... MEMANTIN BASICS 20MG ... EBIXA 5 MG/BASIS ORAL SOLUSYON 50 ML …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … MEMANTIN BASICS 10MG ... MEMANTIN BASICS 20MG ... EBIXA 5 MG/BASIS ORAL SOLUSYON 50 ML …
Zanidatamab
According to Zymeworks, "ZW25 is a bispecific antibody that can simultaneously bind two non-overlapping epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and removal of HER2 protein from the cell surface, and potent effector function. These combined mechanisms of action have led to...
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS ERBB2 (EPIDERMAL GROWTH FACTOR RECEPTOR 2, RECEPTOR TYROSINEPROTEIN …
Matched Description: … removal of HER2 protein from the cell surface, and potent effector function. ... epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and ... combined mechanisms of action have led to significant anti-tumor activity in preclinical models of breast and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … removal of HER2 protein from the cell surface, and potent effector function. ... epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and ... combined mechanisms of action have led to significant anti-tumor activity in preclinical models of breast and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tasonermin
Tasonermin is recombinant soluble form tumor necrosis factor α produced via Escherichia coli cell culture. It was approved for use by the European Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and in palliative care for irresectable soft...
Approved
Matched Synonyms: … Tumor necrosis factor, soluble form, nonglycosylated …
Matched Description: … Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and ... Tasonermin is recombinant soluble form tumor necrosis factor α produced via _Escherichia coli_ …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and ... Tasonermin is recombinant soluble form tumor necrosis factor α produced via _Escherichia coli_ …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
PF-05230907
PF-05230907 is a recombinant activated Factor X variant.
Investigational
Matched Synonyms: … RECOMBINANT FACTOR XA VARIANT FXAI16L …
Matched Description: … PF-05230907 is a recombinant activated Factor X variant. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Biological Factors ... Blood Coagulation Factors …
Matched Description: … PF-05230907 is a recombinant activated Factor X variant. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Biological Factors ... Blood Coagulation Factors …
Molgramostim
Molgramostim has been used in trials studying the treatment of Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and Autoimmune Pulmonary Alveolar Proteinosis.
Investigational
Matched Synonyms: … Granulocyte macrophage-colony stimulating factor …
Matched Description: … Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and …
Matched Categories: … Hematopoietic Cell Growth Factors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Biological Factors …
Matched Description: … Bronchiectasis, Cystic Fibrosis, Pulmonary Alveolar Proteinosis, Acute Respiratory Distress Syndrome, and …
Matched Categories: … Hematopoietic Cell Growth Factors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Biological Factors …
Methylene blue
Methylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered...
Approved
Investigational
Matched Synonyms: … Basic Blue 9 ... C.I. basic blue 9 …
Matched Description: … The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult ... Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and ... proposed trade name Rember) is an investigational drug being developed by the University of Aberdeen and …
Matched Description: … The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult ... Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and ... proposed trade name Rember) is an investigational drug being developed by the University of Aberdeen and …
Hyaluronidase (human recombinant)
A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzyme used to improve the absorption and dispersion of...
Approved
Investigational
Matched Synonyms: … Hyaluronidase, human ... Hyaluronidase human recombinant ... Hyaluronidase (human recombinant) …
Matched Name: … Hyaluronidase (human recombinant) …
Matched Description: … fluids, drugs, and contrast agents. ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. ... [A4033] Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Name: … Hyaluronidase (human recombinant) …
Matched Description: … fluids, drugs, and contrast agents. ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. ... [A4033] Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Hexapeptide-2
Investigational
Matched Synonyms: … Growth hormone releasing hexapeptide ... Growth hormone-releasing peptide 6 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Growth Hormone-Releasing Hormone …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Growth Hormone-Releasing Hormone …
Displaying drugs 501 - 525 of 1064 in total